Shock, Sepsis, and Organ Failure — Nitric Oxide

1. Front Matter

   Pages I-XIII

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2. Nitric Oxide and Cardiovascular Dysfunction in Sepsis and Endotoxaemia: An Introduction and an Overview

   • J. R. Parratt

   Pages 1-29

3. Inhibition of Induction or Activity of Nitric Oxide Synthase: Novel Approaches for the Therapy of Circulatory Shock

   • C. Thiemermann

   Pages 30-58

4. Involvement of Endotoxin, Tumour Necrosis Factor, and Nitric Oxide in Haemorrhagic Shock-Related Alterations

   • S. Bahrami, G. Schlag, Y.-M. Yao, H. Redl

   Pages 59-83

5. The Role of Nitric Oxide in Hemorrhagic Shock and Trauma

   • J. B. Ochoa, T. R. Billiar, A. B. Peitzman

   Pages 84-101

6. Induction by Endotoxin of Nitric Oxide Production in Vascular Smooth Muscle Cells

   • J. C. Stoclet, C. A. Schott, F. Schneider, C. Berton, D. Paya

   Pages 102-120

7. Nitric Oxide: A Modulator of Cell-Cell Adhesion and Protein Exchange in Postcapillary Venules

   • D. N. Granger, I. Kurose, P. Kubes

   Pages 121-136

8. Pathogenetic Mechanisms in Gram-Positive Shock: Studies on the Ability of Streptococcus pyogenes to Induce Nitric Oxide In Vitro

   • P. Mills, T. Evans, J. Cohen

   Pages 137-152

9. Septic Shock: A Central Role for Nitric Oxide

   • R. G. Kilbourn

   Pages 153-179

10. The Role of Nitric Oxide in Vascular Haemostasis and Thrombosis: Implications for Septicaemia and Cell Damage

    • M. W. Radomski

    Pages 180-197

11. Inhibition of Nitric Oxide Synthase During Sepsis and Endotoxemia May Be Detrimental

    • P. O. Hasselgren, J. E. Fischer, T. A. Meyer, G. Tiao

    Pages 198-220

12. Induction of GTP-Cyclohydrolase I by Bacterial Lipopolysaccharide: Implications for Nitric Oxide Formation

    • E. R. Werner, H. Wachter, G. Werner-Felmayer

    Pages 221-238

13. Nitric Oxide Inhalation Therapy in Lung Failure

    • P. Germann, A. Balassa, G. Pöschl, G. Röder, W. Vlach, B. Faryniak et al.

    Pages 239-242

14. Vasodilators in Sepsis

    • M. Booke, L. D. Traber, D. L. Traber

    Pages 243-264

15. The Nitric Oxide Pathway in the Control of Myocardial Function: Role of Cytokines

    • R. A. Kelly, D. Ungureanu-Longrois, J.-L. Balligand, T. W. Smith

    Pages 265-285

16. Nitric Oxide Dependent and Independent Effects of Tumor Necrosis Factor-α on Cardiomyocyte Beating Activity and Signal Transduction Pathways

    • K. Werdan, U. Müller-Werdan, C. Reithmann, P. Boekstegers, R. Fuchs, I. Kainz et al.

    Pages 286-309

17. Effect of Nitrosylated Albumin in the Isolated Rabbit Heart

    • S. Hallström, H. Gasser, W. Hödl, M. Thurnher, K. Kropik, G. Schlag

    Pages 310-321

18. Myocardial Depression in Septic Shock: Role of Nitric Oxide and Other Mediators

    • A. Kumar, J. E. Parrillo

    Pages 322-343

19. Comments to NO in Trauma

    • G. Schlag

    Pages 344-346

20. Back Matter

    Pages 347-355

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International experts examine the role of nitric oxide in various metabolic events such as septic shock, cardiovascular dysfunction, and trauma and hemorrhagic shock. The nitric oxide pathway and nitric oxide synthesis regulation are also discussed.

• Nitric Oxide
• cardiovascular
• muscle
• necrosis
• organ
• regulation
• sepsis
• shock
• thrombosis
• trauma
• tumor

• Ludwig-Boltzmann-Institut für experimentelle und klinische Traumatologie, Wien, Austria

  Günther Schlag, Heinz Redl

Policies and ethics