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Molecular and Cellular Mechanisms of H+ Transport

  • Conference proceedings
  • © 1994

Overview

Editors:
  1. Barry H. Hirst

    1. Department of Physiological Sciences, University of Newcastle upon Tyne Medical School, Newcastle upon Tyne, UK

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Table of contents (55 papers)

  1. Front Matter

    Pages I-X
    Download chapter PDF

  2. Gastric H+, K+-ATPase

    1. Gene Structure and Regulation of Gastric Proton Pump

      • Mesatomo Maeda
      Pages 1-10

    2. The Gastric H/K ATPase β Subunit Gene and Transcriptional Pathways in Acid-Secreting Epithelia of the Stomach and Kidney

      • Ian R. van Driel, Paul A. Gleeson, Seong-Seng Tan, Ban-Hock Toh
      Pages 11-18

    3. Functional Expression of Gastric H,K-ATPase in Sf9 Cells using the Baculovirus Expression System

      • Corné H. W. Klaassen, Tom J. F. Van Uem, Mariëlle P. De Moel, Godelieve L. J. De Caluwé, Herman G. P. Swarts, Jan Joep H. H. M. De Pont
      Pages 19-26

    4. Structural and Functional Integrity of H,K-ATPase Depends β-Subunit

      • John G. Forte, Dar C. Chow
      Pages 27-34

    5. The Topology of the α, β Subunits of the Gastric H/K ATPase

      • Jai Moo Shin, Krister Bamberg, Marie Besancon, Keith Munson, Frederic Mercier, Dennis Bayle et al.
      Pages 35-53

    6. Synthetic Peptide Antibody Probes of Membrane Orientation of the Gastric H,K-ATPase

      • Adam Smolka
      Pages 55-62

    7. Molecular Determinants of Subunit Assembly and Processing in Na,K-ATPase and H,K-ATPase

      • Käthi Geering, Philippe Jaunin, Ahmed Beggah, Frédéric Jaisser
      Pages 63-69

    8. Assembly of Hybrid Pumps from Na,K-ATPase α Subunits and the H,K-ATPase β Subunit

      • Robert A. Farley, Kurt A. Eakle
      Pages 71-78

    9. DCCD Inhibition of Cation Binding in the Gastric H,K-ATPase

      • Edd C. Rabon, Kent Smillie
      Pages 79-87

    10. Mapping of a Cytoplasmic Site of Gastric (H+,K+)-ATPase involved in the Transmission of K+-Activation across the Membrane

      • D. Bayle, J. C. Robert, A. Soumarmon, R. Brasseur, H. G. P. Swarts, C. H. W. Klaassen et al.
      Pages 89-94

    11. New Approaches to Inhibition of Gastric Acid Secretion: Development and Mechanism of Omeprazole

      • Björn Wallmark
      Pages 95-102

    12. K+-Competitive Inhibitors of the Gastric (H++K+)-Atpase

      • David J. Keeling
      Pages 103-110

    13. Bioactive Peptide Inhibitors and An Endogenous Parietal Cell Protein: Interactions With the Gastric H+/K+ ATPase

      • John Cuppoletti, Pingbo Huang, Danuta H. Malinowska
      Pages 111-118

    14. The Gastric H/K-ATPase: The Principle Target in Autoimmune Gastritis

      • Paul A. Gleeson, Ban-Hock Toh, Frank Alderuccio, Ian R. van Driel
      Pages 119-126

  3. Non-gastric transport-ATPases

    1. Acidic and non-acidic endosomes in kidney epithelial cells: their role in cell-specific membrane recycling processes

      • Dennis Brown, Ivan Sabolić
      Pages 127-136

    2. Regulation and Properties of the Coated Vesicle Proton Pump

      • Yu Feng, Melanie Myers, Michael Forgac
      Pages 137-144

    3. Characterization of the Osteoclast Vacuolar H+ ATPase: Biochemistry, Subunit Composition and Cloning of Catalytic Subunits

      • Roland Baron, Marcjanna Bartkiewicz, Diptendu Chatterjee, Munmun Chakraborty, Pe’er David, Chris Fabricant et al.
      Pages 145-151

    4. The Renal H-K-ATPase: Function and Expression

      • Charles S. Wingo, Xiaoming Zhou, Adam Smolka, Kirsten Madsen, C. Craig Tisher, Kevin A. Curran et al.
      Pages 153-161

    5. Apical K+-ATPase and Active Potassium Absorption in the Distal Colon

      • Henry J. Binder
      Pages 163-171
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Keywords

About this book

Reviewed here is the current knowledge of proton transport mechanisms in mammals. The emphasis is on gastric acid secretion and the role of the H+, K+-ATPase, but molecular and cellular information on other P-, V- and F-type H+-ATPases, in bone, kidney, plants and yeast, as well as other cation ATPases, are included for important comparisons. The role of proton/anion antiports, symports and channels in proton transport is discussed. Further attention is given to the regulation of proton transport mechanisms and cellular mechanisms to resist damage from highly acidic environments.

Editors and Affiliations

  • Department of Physiological Sciences, University of Newcastle upon Tyne Medical School, Newcastle upon Tyne, UK

    Barry H. Hirst

Bibliographic Information

  • Book Title: Molecular and Cellular Mechanisms of H+ Transport

  • Editors: Barry H. Hirst

  • DOI: https://doi.org/10.1007/978-3-642-79301-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 1994

  • Softcover ISBN: 978-3-642-79303-5Published: 22 November 2011

  • eBook ISBN: 978-3-642-79301-1Published: 29 June 2013

  • Edition Number: 1

  • Number of Pages: X, 494

  • Topics: Biochemistry, general, Cell Biology

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