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  • Conference proceedings
  • © 1996

Acute Leukemias V

Experimental Approaches and Management of Refractory Disease

Editors:

  1. W. Hiddemann

    1. Department of Internal Medicine, University of Göttingen, Göttingen, Germany

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  2. W. Plunkett

    1. Department of Internal Medicine, University of Göttingen, Göttingen, Germany

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  3. T. Büchner

    1. Department of Internal Medicine, University of Münster, Münster, Germany

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  4. J. Ritter

    1. Department of Pediatric Oncology, University of Münster, Münster, Germany

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  5. B. Wörmann

    1. Department of Internal Medicine, MD Anderson Cancer Center, Houston, USA

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  6. M. J. Keating

    1. Department of Internal Medicine, MD Anderson Cancer Center, Houston, USA

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  7. U. Creutzig

    1. Koordinierungsstelle, Deutsche Krebsgesellschaft e.V., Hannover, Germany

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Part of the book series: Haematology and Blood Transfusion Hämatologie und Bluttransfusion (HAEMATOLOGY, volume 37)

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Table of contents (105 papers)

  1. Front Matter

    Pages I-XXVI
    PDF

  2. Leukemia Cell Biology

    1. Front Matter

      Pages 1-1
      PDF

    3. CD34 and CD38 Expression on Blasts in Myelodysplastic Syndromes and Secondary AML

      • W. Verbeek, C. Ries, D. Grove, M. Unterhalt, W. Hiddemann, B. Wörmann
      Pages 11-14

    4. Heterogeneity of HRX-FEL Fusion Transcripts in Adult and Pediatric t(4;11) ALL

      • F. Griesinger, T. Jahn, H. Elfers, W.-D. Ludwig, M. Falk, H. Rieder et al.
      Pages 15-21

  3. Pharmacokinetics — Clinical Implications

    1. Front Matter

      Pages 23-23
      PDF

    2. Fludarabine and Ara-C Combination for Treatment of Adult Acute Myelogenous Leukemia: Pharmacokinetic and Pharmacodynamic Effects

      • Varsha Gandhi, Min Du, Amy J. Chapman, Peng Huang, Elihu Estey, Michael J. Keating et al.
      Pages 25-31

    3. Pharmacokinetics of Ara-CMP-Stearate (YNK01) — Phase I Study of the Oral Ara-C Derivative

      • Jan Braess, Eberhard Schleyer, Bernhard Ramsauer, Michael Unterhalt, Cornelia Kaufmann, Sabine Wilde et al.
      Pages 32-40

    4. Differential Effect of GM-CSF on the Intracellular Ara-C Metabolism in Normal Bone Marrow Mononuclear Cells and Acute Myeloid Leukemia (AML) Blasts

      • Christoph Reuter, Claus Rolf, Eberhard Schleyer, Michael Unterhalt, Bernhard Woermann, Thomas Buechner et al.
      Pages 41-49

    5. Intracellular Retention of Cytosine-Arabinoside-Triphosphate in Leukemic Blast Cells from Children

      • J. Boos, M. Schiller, B. Pröbsting, U. Creutzig, J. Ritter
      Pages 50-53

    7. Targeted Drug Therapy in Childhood Acute Lymphoblastic Leukemia

      • Mary V. Relling, Ching-Hon Pui, William E. Evans
      Pages 62-66

    8. Asparagine Levels in Children on E. Coli- and Erwinia-Asparaginase Therapy

      • J. Boos, G. Werber, E. Verspohl, E. Ahlke, U. Nowak-Göttl, H. Jürgens
      Pages 67-69

  4. Chemo-Resistance

    1. Front Matter

      Pages 71-71
      PDF

    2. Pharmacologic Modulation of Multidrug Resistance in Acute Leukemia: Results and Challenges

      • Alan F. List, Betty Glinsmann-Gibson, William S. Dalton
      Pages 73-78

    6. Expression of P-Glycoprotein in Children and Adults with Leukemia — Correlation with Clinical Outcome

      • Slawomir Kaczorowski, Maria Ochocka, Robert Aleksandrowicz, Maria Kaczorowska, Michal Matysiak, Marek Karwacki
      Pages 101-107

    7. Multidrug Resistance in Acute Myelogenous Leukemia: Relevance to Clinical and Laboratory Data

      • Andrey Zaritskey, Irina Stuf, Tatyana Bykova, Kirill Titov, Nadezhda Medvedeva, Natalya Anikina et al.
      Pages 108-111
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About this book

150 years after the first description of the clinical picture of "white blood" and the introduction of the term "leukemia" by R. Virchow it appears, that the leukemias, and the acute leukemias in particular, serve as an impressive example for the major improvements that have been achieved in the treatment but also in the understand­ ing of the biology of malignant dis orders. The international symposia "Acute Leukemia" which are held at Münster since 1986 have developed into an interna­ tional forum to review the current progress and the future perspectives of leukemia research and therapy at a high scientific and clinicallevel. Since the possibility for active participation in these symposia is somewhat restricted we are glad to have the opportunity to extend the information that was presented at the symposium "Acute Leukemias V - Experimental Approaches and Management of Refractory Disease" which was held from February 27 to March 2, 1994 to a broader audience of basic scientists and clinicians. This meeting was especiaIly designed to discuss experimen­ tal approaches and the management of refractory disease which allows to evaluate new experimental therapies on the basis of preclinical studies.
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Keywords

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Editors and Affiliations

  • Department of Internal Medicine, University of Göttingen, Göttingen, Germany

    W. Hiddemann, W. Plunkett

  • Department of Internal Medicine, University of Münster, Münster, Germany

    T. Büchner

  • Department of Pediatric Oncology, University of Münster, Münster, Germany

    J. Ritter

  • Department of Internal Medicine, MD Anderson Cancer Center, Houston, USA

    B. Wörmann, M. J. Keating

  • Koordinierungsstelle, Deutsche Krebsgesellschaft e.V., Hannover, Germany

    U. Creutzig

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Bibliographic Information

  • Book Title: Acute Leukemias V

  • Book Subtitle: Experimental Approaches and Management of Refractory Disease

  • Editors: W. Hiddemann, W. Plunkett, T. Büchner, J. Ritter, B. Wörmann, M. J. Keating, U. Creutzig

  • Series Title: Haematology and Blood Transfusion Hämatologie und Bluttransfusion

  • DOI: https://doi.org/10.1007/978-3-642-78907-6

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1996

  • Softcover ISBN: 978-3-642-78909-0Published: 01 December 2012

  • eBook ISBN: 978-3-642-78907-6Published: 17 April 2013

  • Series ISSN: 0440-0607

  • Edition Number: 1

  • Number of Pages: XXVI, 613

  • Number of Illustrations: 54 b/w illustrations

  • Topics: Hematology, Oncology

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Buy it now

eBook USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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