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Skin Cancer: Basic Science, Clinical Research and Treatment

  • Conference proceedings
  • © 1995

Overview

Editors:
  1. Claus Garbe

    1. University Department of Dermatology Medical Centre Benjamin Franklin, Freie Universität Berlin, Berlin, Germany

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  2. Stefan Schmitz

    1. University Department of Dermatology Medical Centre Benjamin Franklin, Freie Universität Berlin, Berlin, Germany

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  3. Constantin E. Orfanos

    1. University Department of Dermatology Medical Centre Benjamin Franklin, Freie Universität Berlin, Berlin, Germany

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Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 139)

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Table of contents (34 papers)

  1. Front Matter

    Pages I-XVI
    Download chapter PDF

  2. Carcinogenesis

    1. Differentiation and Tumor Progression

      • N. E. Fusenig, D. Breitkreutz, P. Boukamp, P. Tomakidi, H.-J. Stark
      Pages 1-19

    2. Action Spectrum for Photocarcinogenesis

      • F. R. de Gruij
      Pages 21-30

    3. Processing of Directly and Indirectly Ultraviolet-Induced DNA Damage in Human Cells

      • T. M. Rünger, B. Epe, K. Möller
      Pages 31-42

    4. Photodynamic Action of Ultraviolet A: Induction of Cellular Hydroperoxides

      • S. Schmitz, C. Garbe, K. Jimbow, A. Wulff, H. Daniels, J. Eberle et al.
      Pages 43-55

    5. Analysis of N-ras Mutations in Human Cutaneous Melanoma: Tumor Heterogeneity Detected by Polymerase Chain Reaction/Single-Stranded Conformation Polymorphism Analysis

      • A. van Elsas, S. Zerp, S. van der Flier, M. Krüse-Wolters, A. Vacca, D. J. Ruiter et al.
      Pages 57-67

    6. Skin Cancer and Warts in Immunosuppressed Renal Transplant Recipients

      • I. M. Leigh, M. T. Glover
      Pages 69-86

    7. Risk of Developing Cutaneous Malignant Melanoma in Atypical-Mole Syndrome: New York University Experience and Literature Review

      • J. Slade, T. G. Salopek, A. A. Marghoob, A. W. Kopf, D. S. Rigel
      Pages 87-104

  3. Malignant Melanoma

    1. Properties of Metastasizing and Nonmetastasizing Human Melanoma Cells

      • G. N. P. van Muijen, E. H. J. Danen, T. J. de Vries, P. H. A. Quax, J. H. Verheijen, D. J. Ruiter
      Pages 105-122

    2. Protein Patterns of Benign and Malignant Human Melanocytes Show Consistent Changes in Gene Expression

      • J. Eberle, C. Garbe, G. Kroumpouzos, C. E. Orfanos
      Pages 123-135

    3. Mutation and Expression of TP53 in Malignant Melanomas

      • J. Weiss, M. Heine, K. C. Arden, B. Körner, H. Pilch, R. A. Herbst et al.
      Pages 137-154

    4. Production of Cytokines by Human Melanoma Cells and Melanocytes

      • S. Krüger-Krasagakes, K. Krasagakis, C. Garbe, T. Diamantstein
      Pages 155-168

    5. Growth Control of Melanoma Cells and Melanocytes by Cytokines

      • K. Krasagakis, C. Garbe, Ch. C. Zouboulis, C. E. Orfanos
      Pages 169-182

    6. Effects of Various Synthetic Retinoids on Proliferation and Immunophenotype of Human Melanoma Cells In Vitro

      • D. Schadendorf, M. Worm, K. Jurgovsky, E. Dippel, U. Reichert, B. M. Czarnetzki
      Pages 183-193

    7. Prognostic Significance of DNA Cytometry in Comparison with Histologic Measurements in Malignant Melanomas

      • T. Vogt, W. Stolz, U. Hohenleutner, R. Schiffner, M. Landthaler
      Pages 195-204

    8. Lymphocyte-Melanoma Interaction: Role of Surface Molecules

      • J. C. Becker, E. B. Bröcker
      Pages 205-214

    9. Melanoma Control in the United States: Current Status

      • H. K. Koh, A. C. Geller
      Pages 215-224

  4. Cutaneous Lymphoma

    1. New Perspectives in Experimental and Clinical Research for Cutaneous T Cell Lymphomas

      • G. Burg, A. Häffner, R. Böni, S. Dommann, R. Dummer
      Pages 225-237

    2. Use of Polymerase Chain Reaction in the Detection of Clones in Lymphoproliferative Diseases of the Skin

      • G. Staib, W. Sterry
      Pages 239-247

    3. bcl-1, bcl-2, p53, c-myc, and lyt-10 Analysis in Cutaneous Lymphomas

      • S. A. Garatti, E. Roscetti, D. Trecca, N. S. Fracchiolla, A. Neri, E. Berti
      Pages 249-261
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Keywords

About this book

In the past two decades, considerable interest in skin cancer has developed in the public and scientific communities. There may have been several reasons for this: - The rise in the global incidence of cutaneous cancers - New molecular biology techniques resulting in a better understanding of pathogenesis and improved diagnostic procedures - The advent of new pathological entities, e. g. , the endemic form of Kaposi's sarcoma - A constantly increasing range of therapeutic modalities, providing even more efficacious treatment and manage­ ment of skin cancers As N. E. Fusenig describes in the first chapter of this volume, basic research is only beginning to unravel the complex mechanism involved in cellular dedifferentiation and tumor progression. Progress is dearly needed, especially in dermato­ oncology, where the rise in the incidence of epithelial tumors has inflated the overall skin cancer incidence. The incidence of tumors of the skin exceeds that of all other neoplasias in humans, with recreational sun exposure being a suspected primary cause. Several studies on the effects of UV radiation have been included at the beginning of this volume. Even the role of long wavelength UV (UVA) has become a focus of research activities. The main concern is that the low carcinogenicity of UVA, in comparison to UVB, may be outweighed and exceeded in its effects by increased UV A exposure, e. g.

Editors and Affiliations

  • University Department of Dermatology Medical Centre Benjamin Franklin, Freie Universität Berlin, Berlin, Germany

    Claus Garbe, Stefan Schmitz, Constantin E. Orfanos

Bibliographic Information

  • Book Title: Skin Cancer: Basic Science, Clinical Research and Treatment

  • Editors: Claus Garbe, Stefan Schmitz, Constantin E. Orfanos

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-642-78771-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1995

  • Softcover ISBN: 978-3-642-78773-7Published: 27 December 2011

  • eBook ISBN: 978-3-642-78771-3Published: 06 December 2012

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: XVI, 440

  • Topics: Oncology, Dermatology, Surgery

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