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Soft Tissue Sarcomas in Adults

  • Conference proceedings
  • © 1995

Overview

Editors:
  1. M. Bamberg

    1. Department of Radiotherapy, University of Tübingen, Tübingen, Germany

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  2. W. Hoffmann

    1. Department of Radiotherapy, University of Tübingen, Tübingen, Germany

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  3. D. K. Hossfeld

    1. Department of Hematology and Oncology, University of Hamburg, Hamburg, Germany

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Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 138)

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Table of contents (19 papers)

  1. Front Matter

    Pages I-XI
    Download chapter PDF

  3. Local Treatment of Soft Tissue Sarcomas

    1. Limb Salvage and Reconstructive Procedures in Soft Tissue Sarcomas of the Extremities

      • H. U. Steinau, R. Büttemeyer, P. Vogt, J. Hussmann, D. Hebebrand
      Pages 31-39

    2. Surgical Management of Truncal and Head/Neck Soft Tissue Tumours

      • J. M. Thomas
      Pages 41-45

    3. Combined Surgery and Radiotherapy for Conservative Management of Soft Tissue Sarcomas

      • E. B. Hug, I. J. Spiro, D. J. Cole, H. D. Suit
      Pages 47-55

    4. Role of Brachytherapy in the Treatment of Soft Tissue Sarcomas of the Extremities — Techniques and Results

      • D. Nori, B. S. Hilaris
      Pages 57-71

    5. Radiotherapy in the Treatment of Inoperable and Advanced Soft Tissue Sarcomas in Adults

      • M. Bamberg, H. Schmidberger, W. Hoffmann
      Pages 73-79

    6. Regional Hyperthermia Combined with Systemic Chemotherapy of Locally Advanced Sarcomas: Preclinical Aspects and Clinical Results

      • R. D. Issels
      Pages 81-90

  4. Local Recurrences and Disseminated Disease

    1. Histological Characteristics of Local Recurrences in Soft Tissue Sarcomas

      • C. D. M. Fletcher
      Pages 91-94

    2. Local Recurrences of Soft Tissue Sarcomas — A Therapeutic Challenge

      • V. Budach, M. Stuschke, W. Budach
      Pages 95-108

    3. Histomorphological Characteristics of Metastases of Soft Tissue Sarcomas

      • D. Schmidt
      Pages 109-116

    4. Radiotherapy in the Treatment of Metastases of Soft Tissue Sarcomas

      • W. Hoffmann, R. D. Kortmann, M. Bamberg
      Pages 117-121

    5. Results of Surgical Treatment of Pulmonary Metastases from Soft Tissue Sarcomas

      • J. Schirren, S. Krysa, H. Bülzebruck, A. Zweibarth, P. Schneider, P. Drings et al.
      Pages 123-138

  5. Systemic Treatment

    1. Adjuvant Chemotherapy of Soft Tissue Sarcomas in North America

      • R. S. Benjamin
      Pages 139-145

    2. Systemic Therapy of Disseminated Soft Tissue Sarcomas

      • H. J. Weh, D. K. Hossfeld
      Pages 147-159

  6. New Developments and Future Aspects

    1. Isolation Perfusion with Tumor Necrosis Factor-α, Interferon-γ, and Hyperthermia in the Treatment of Localized and Metastatic Cancer

      • J. C. Yang, D. L. Fraker, A. K. Thom, H. I. Pass, S. A. Rosenberg
      Pages 161-166

    2. Radiosensitivity and Local Tumor Control — Experimental Studies

      • V. Budach, M. Stuschke, W. Budach
      Pages 167-171
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Keywords

About this book

Sarcomas represent a group of rare tumors which arise from the largest tissue compartment of the body, but account only for about 1 % of all malignancies. Among this group of tumors, soft tissue sarcomas in adults are, in addition to osteosarcomas, the most important. In the diagnostic workup of soft tissue sarcomas modern radiological investigation methods such as CT and MRI techniques are being critically evaluated. While it is widely accepted that the conventional, stained microscopic specimen is still the cornerstone for properly planned treatment stra­ tegies, immunohistochemistry has come to play an indis­ pensable role in accurate classification. Reviewing the surgical techniques, the treatment of musculo-skeletal malignancies, especially of soft tissue sarcomas, has changed considerably over the past decades. While amputation used to be the surgical treatment of choice limb-saving procedures have now become an im­ portant therapeutic modality in treating such lesions, particularly in combination with percutaneous or interstitial radiotherapy. Despite adequate local treatment, many patients with soft tissue sarcomas will ultimately develop metastatic disease, usually in the lungs. For this reason, effective ad­ juvant systemic treatment should be given simultaneously with or soon after treatment of local disease. The results of several randomized trials evaluating adjuvant chemotherapy have been reported in the meanwhile, indicating im­ proved, disease-free survival with a trend towards improved overall survival. In disseminated disease, drug combi- VI Preface nations or single agents are used as palliative treatment and might help to improve survival in selected subgroups.

Editors and Affiliations

  • Department of Radiotherapy, University of Tübingen, Tübingen, Germany

    M. Bamberg, W. Hoffmann

  • Department of Hematology and Oncology, University of Hamburg, Hamburg, Germany

    D. K. Hossfeld

Bibliographic Information

  • Book Title: Soft Tissue Sarcomas in Adults

  • Editors: M. Bamberg, W. Hoffmann, D. K. Hossfeld

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-642-78768-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1995

  • Softcover ISBN: 978-3-642-78770-6Published: 13 December 2011

  • eBook ISBN: 978-3-642-78768-3Published: 06 December 2012

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: XI, 176

  • Topics: Oncology, Pathology

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