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Use of Mechanistic Information in Risk Assessment

Proceedings of the 1993 EUROTOX Congress Meeting Held in Uppsala, Sweden, June 30–July 3, 1993

  • Conference proceedings
  • © 1994

Overview

Editors:
  1. Hermann M. Bolt

    1. Institut für Arbeitsphysiologie an der Universität Dortmund, Dortmund, Germany

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  2. Björn Hellman

    1. Department of Occupational Medicine, Uppsala University Hospital, Uppsala, Sweden

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  3. Lennart Dencker

    1. Department of Pharmaceutical Biosciences: Toxicology, BMC, Uppsala University, Uppsala, Sweden

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Part of the book series: Archives of Toxicology (TOXICOLOGY, volume 16)

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Table of contents (34 papers)

  1. Front Matter

    Pages I-VIII
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  3. Contact and Respiratory Sensitisation

    1. Front Matter

      Pages 61-61
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    2. Immunoregulation of T cell-mediated skin hypersensitivity

      • Rik J. Scheper, B. Mary, E. von Blomberg
      Pages 63-70

    3. Test Methods for Contact Sensitization

      • Th. Maurer, A. Arthur, Ph. Bentley
      Pages 71-76

    4. Test methods for respiratory sensitization

      • Jürgen Pauluhn
      Pages 77-86

    5. Newer Approaches to the Evaluation of Sensitization Phenomena

      • I. Kimber
      Pages 87-94

    6. Risk Assessment of Sensitizing Agents

      • G. Frank Gerberick
      Pages 95-101
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Keywords

About this book

M. Pliftski Institute of Oceanography, GdaJisk University 46 Pilsudskiego Av. 81-378 Gdynia, Poland 2 The Baltic Sea with 366,000 km is only 0. 1% of the world's oceans but nevertheless, unique in many ways. The Baltic Sea is the largest area of brackish water in the world. As a formation of nature, it is a sea that in many ways resembles a lake. This makes its flora and fauna interesting and well adapted to the brackish water environment. The recent stage of biocoenosis composition is influenced by several features. Historically, during the last glaciation, when the Baltic was sometimes a huge marine bay and sometimes a large, freshwater lake, several ecosystems developed and were successively replaced. The flora and fauna composition of those previous biocoenosis was discovered from the geological layers corresponding to the Yoldic Sea, the Ancylus Lake and the Littorina Sea periods. Recently the marine influence has come from the North Sea water inflow, which greatly affects the salinity of the deep water. The freshwater influence comes from the fluvial water which gives the surface layer a lower salinity value. Salinity in the Baltic regions varies greatly - Gulf of Bothnia 2-4%0, the central Baltic proper 7-13%0, the Kattegat 15-300/00 in the surface water and 32- 34%0 in the bottom water, the Skagerrak 20-300/00 in the surface and 32-35%0 in the bottom water.

Editors and Affiliations

  • Institut für Arbeitsphysiologie an der Universität Dortmund, Dortmund, Germany

    Hermann M. Bolt

  • Department of Occupational Medicine, Uppsala University Hospital, Uppsala, Sweden

    Björn Hellman

  • Department of Pharmaceutical Biosciences: Toxicology, BMC, Uppsala University, Uppsala, Sweden

    Lennart Dencker

Bibliographic Information

  • Book Title: Use of Mechanistic Information in Risk Assessment

  • Book Subtitle: Proceedings of the 1993 EUROTOX Congress Meeting Held in Uppsala, Sweden, June 30–July 3, 1993

  • Editors: Hermann M. Bolt, Björn Hellman, Lennart Dencker

  • Series Title: Archives of Toxicology

  • DOI: https://doi.org/10.1007/978-3-642-78640-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1994

  • Softcover ISBN: 978-3-642-78642-6Published: 29 December 2011

  • eBook ISBN: 978-3-642-78640-2Published: 06 December 2012

  • Series ISSN: 0171-9750

  • Edition Number: 1

  • Number of Pages: VIII, 312

  • Topics: Biochemistry, general, Occupational Medicine/Industrial Medicine, Pharmacology/Toxicology

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