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Principles and Treatment of Lipoprotein Disorders

  • Book
  • © 1994

Overview

Editors:
  1. Gotthard Schettler

    1. Klinisches Institut für Herzinfarktforschung an der Medizinischen Universitätsklinik, University of Heidelberg, Heidelberg, Germany

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  2. Andreas J. R. Habenicht

    1. School of Medicine, Department of Medicine, Division of Endocrinology and Metabolism, University of Heidelberg, Heidelberg, Germany

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Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 109)

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Table of contents (16 chapters)

  1. Front Matter

    Pages I-XXIII
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  2. Physiology and Pathophysiology of Lipid Metabolism

    1. Front Matter

      Pages 1-1
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    2. An Introduction to the Biochemistry and Biology of Blood Lipids and Lipoproteins

      • J. R. Patsch
      Pages 3-27

    3. Lipoprotein Metabolism

      • H. B. Brewer
      Pages 29-51

    4. Lipoprotein Receptors

      • W. J. S. de Villiers, G. A. Coetzee, D. R. van der Westhuyzen
      Pages 53-87

    5. Genetic Disorders of Lipoprotein Metabolism

      • G. Utermann, H. J. Menzel
      Pages 89-138

    6. Interactions Between Lipoproteins and the Arterial Wall

      • A. J. R. Habenicht, P. B. Salbach, U. Janssen-Timmen
      Pages 139-174

    7. Lipoprotein Lipase and Hepatic Lipase

      • T. Olivecrona, G. Olivecrona
      Pages 175-205

    8. Animal Models of Lipoprotein Metabolism

      • D. Kritchevsky
      Pages 207-218

  3. Lipid Lowering Therapy

    1. Front Matter

      Pages 219-219
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    2. Rationale to Treat

      • D. H. Blankenhorn, H. N. Hodis
      Pages 221-245

    3. The Dietary Therapy of Hyperlipidemia: Its Important Role in the Prevention of Coronary Heart Disease

      • W. E. Connor, S. L. Connor
      Pages 247-277

    4. Lipid Apheresis

      • D. Seidel
      Pages 279-300

  4. Lipid Lowering Drugs

    1. Front Matter

      Pages 301-301
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    2. 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase Inhibitors

      • D. R. Illingworth, E. B. Schmidt
      Pages 303-324

    3. Fibrates

      • A. Gaw, C. J. Packard, J. Shepherd
      Pages 325-348

    4. Nicotinic Acid and Derivatives

      • A. G. Olsson
      Pages 349-400

    5. Ion Exchange Resins

      • P. Schwandt, W. O. Richter
      Pages 401-427

    6. Probucol

      • J. Davignon
      Pages 429-469

    7. Miscellaneous Lipid-Lowering Drugs

      • K. J. Lackner, E. von Hodenberg
      Pages 471-492
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Keywords

About this book

Major advances have been made in the understanding of the molecular mechanisms of atherosclerosis, the disease that still affects more than 50 percent of the population in the highly industrialized countries. This volume covers the most recent advances in the treatment of hyperlipidemia. It represents a necessary update because molecular mechanisms of atherogenesis have been discovered in the past few years and their molecular mechanisms of action identified. Extensively treated are the molecular mechanisms of disease etiology of arteriosclerosis in relation to the major risk factor "hyperlipidemia", rationale for more effective treatment of this disease by dietary means, the treatment of associated or causing diseases, and the treatment using hypolipidemic drugs.

Editors and Affiliations

  • Klinisches Institut für Herzinfarktforschung an der Medizinischen Universitätsklinik, University of Heidelberg, Heidelberg, Germany

    Gotthard Schettler

  • School of Medicine, Department of Medicine, Division of Endocrinology and Metabolism, University of Heidelberg, Heidelberg, Germany

    Andreas J. R. Habenicht

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