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Lectins and Glycobiology

  • Book
  • © 1993

Overview

Editors:
  1. Hans-Joachim Gabius

    1. Institut für Physiologische Chemie, Ludwig-Maximilians-Universität, München, Germany

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  2. Sigrun Gabius

    1. Institut für Physiologische Chemie, Ludwig-Maximilians-Universität, München, Germany

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Springer Lab Manuals (SLM)

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Table of contents (55 chapters)

  1. Front Matter

    Pages I-XX
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  2. Introduction

    1. Front Matter

      Pages 1-1
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    2. Lectins: Insights into the State of Knowledge by Literature Searches

      • Dieter H. Gauss
      Pages 3-5

  3. Chemical Synthesis of Lectin Ligands

    1. Front Matter

      Pages 7-7
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    2. Synthetic Ligands for Lectins

      • Reiko T. Lee, Yuan Chuan Lee
      Pages 9-22

    3. Sugar-Polyacrylamide Conjugates as Probes for Cell Lectins

      • N. V. Bovin
      Pages 23-28

  4. Purification and Characterization of Lectins

    1. Front Matter

      Pages 29-29
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    2. Isolation of Plant Lectins

      • H. Rüdiger
      Pages 31-46

    3. A General Procedure for the Purification of Fimbrial Lectins from Escherichia Coli

      • E. Van Driessche, R. Sanchez, S. Beeckmans, F. De Cupere, G. Charlier, P. Pohl et al.
      Pages 47-54

    4. Isolation, Detection, and Ligand Binding Specificity of a Lectin Uniquely Found in Rat Kupffer Cells

      • Jeffery D. Greene, Robert L. Hill
      Pages 55-64

    5. Galaptin: Isolation, Electrophoretic Analysis, Peptide Preparation for Sequencing, and Carbohydrate-Binding Site Specificity

      • Howard J. Allen, Ashu Sharma, Edward C. Kisailus
      Pages 65-80

    6. Determination of Carbohydrate Specificity in Solid-Phase Assays

      • F.-Y. Zeng, H.-J. Gabius
      Pages 81-85

    7. Analysis of Isoelectric Variants of Carbohydrate Binding Protein 35

      • Elizabeth A. Cowles, Richard L. Anderson, John L. Wang
      Pages 86-97

    8. Chemical Modification of Lectins by Group-Specific Reagents

      • F.-Y. Zeng, H.-J. Gabius
      Pages 98-101

  5. Biophysical Methods for the Characterization of Lectin-Ligand Interactions

    1. Front Matter

      Pages 103-103
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    2. Study of Oligosaccharide-Lectin Interaction by Various Nuclear Magnetic Resonance (NMR) Techniques and Computational Methods

      • H. C. Siebert, R. Kaptein, J. F. G. Vliegenthart
      Pages 105-116

    3. Lectin-Glycoconjugate Cross-Linking Interactions

      • D. K. Mandal, C. F. Brewer
      Pages 117-128

    4. Lectins as Analytical Probes to Define the Physical Characteristics of Binding Events

      • P. L. Mann, C. Hanosh, C. M. Tellez, R. Wenk, R. Diaz
      Pages 129-137

  6. Lectins as Tools for the Characterization of Glycoconjugates

    1. Front Matter

      Pages 139-139
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    2. Glycoprotein-Lectin-Immunosorbent Assay (GLIA)

      • E. Köttgen, A. Kage, B. Hell, C. Müller, R. Tauber
      Pages 141-149
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Keywords

About this book

The intriguing complexity, precision, and regulation of the wide range of biologi­ cal processes is determined by intricate mechanisms of molecular recognition. Their nature is under intense scrutiny. In addition to the well-appreciated interac­ tion of proteins either with amino acid or nucleotide sequences, the investigation of their interplay with carbohydrate elements of cellular glycoconjugates current­ ly exerts increasing attraction. In the group of carbohydrate-binding proteins, lec­ tins are distinguished from antibodies or ligand-affecting enzymes, according to the most recent definition. The thorough analysis of their structure and function is considered as a focus to collect a critical mass of information for delineating details of a further array of biochemical processes with pivotal physiological im­ pact. Following an already century-long history of scientific description, reflected by subjectively chosen highlights (see the Brief History of Lectin Research at page VI), the excitement in glycobiological research that prevails today can easily be ex­ plained by our growing awareness of the multifarious significance of a sugar-code system of biological information. This present notion unmistakably has an im­ pact on lines of research in diverse disciplines like cell and molecular biology, histochemistry, or clinical sciences. It also prompts inherent practical questions such as how to obtain lectins, or how to employ them as instruments in various assay systems with the best possible results. Thus, this book is devoted intentionally to cover the techniques in different research fields that deal with lectins.

Editors and Affiliations

  • Institut für Physiologische Chemie, Ludwig-Maximilians-Universität, München, Germany

    Hans-Joachim Gabius, Sigrun Gabius

Bibliographic Information

  • Book Title: Lectins and Glycobiology

  • Editors: Hans-Joachim Gabius, Sigrun Gabius

  • Series Title: Springer Lab Manuals

  • DOI: https://doi.org/10.1007/978-3-642-77944-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1993

  • Softcover ISBN: 978-3-642-77946-6Published: 16 December 2011

  • eBook ISBN: 978-3-642-77944-2Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XX, 521

  • Topics: Cell Biology, Biochemistry, general, Pharmacology/Toxicology, Pathology

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