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Herpes Simplex Virus

Pathogenesis, Immunobiology and Control

  • Book
  • © 1992

Overview

Editors:
  1. Barry T. Rouse

    1. Department of Microbiology, College of Veterinary Medicine, University of Tennessee, Knoxville, USA

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Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 179)

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Table of contents (10 chapters)

  1. Front Matter

    Pages I-IX
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  2. Regulation of Herpes Simplex Virus Type 1 Gene Expression

    • J. Hay, W. T. Ruyechan
    Pages 1-14

  3. Pathogenesis of Herpes Simplex Virus Infection and Animal Models for Its Study

    • L. R. Stanberry
    Pages 15-30

  4. The Role of Immune Mechanisms in Control of Herpes Simplex Virus Infection of the Peripheral Nervous System

    • A. Simmons, D. Tscharke, P. Speck
    Pages 31-56

  5. The Role of T Cell Immunity in Control of Herpes Simplex Virus

    • D. S. Schmid, B. T. Rouse
    Pages 57-74

  6. The Role of Antibody in Herpes Simplex Virus Infection in Humans

    • S. Kohl
    Pages 75-88

  7. Macrophages and Other Nonspecific Defenses: Role in Modulating Resistance Against Herpes Simplex Virus

    • L. Wu, P. S. Morahan
    Pages 89-110

  8. The Role of Herpes Simplex Virus Glycoproteins in Immune Evasion

    • G. Dubin, N. O. Fishman, R. J. Eisenberg, G. H. Cohen, H. M. Friedman
    Pages 111-120

  9. Immunopathology of Herpes Simplex Virus Infections

    • M. Z. Doymaz, B. T. Rouse
    Pages 121-136

  10. Contemporary Approaches to Vaccination Against Herpes Simplex Virus

    • R. L. Burke
    Pages 137-158

  11. Controlling Herpes Simplex Virus Infections: is Intracellular Immunization the Way of the Future?

    • K. K. Wong Jr., S. Chatterjee
    Pages 159-174

  12. Back Matter

    Pages 175-182
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Keywords

About this book

Although upstaged by the tragic appearance of the human immunodeficiency virus, herpes simplex viruses (HSV) types 1 and 2 continue to be major human pathogens against which we lack acceptable vaccines or other means of immunological control. The virus is large and complex, coding for 70 or more proteins. Although many mysteries remain to be unraveled, our knowledge base regarding genomic organization, gene expression and regulation, pathogenesis, and immune recog­ nition of component parts is quite considerable. Indeed, meet­ ings devoted entirely to herpesviruses are conspicuous by their frequency and excellent, yet sometimes exclusive, attendance. The purpose of this volume is to compile in a single book a series of reviews by leading investigators that deal with various aspects of virus-host interactions and which hopefully will pro­ vide clues as to how to best manage HSV from an immunobio­ logical perspective. Ultimately, one anticipates that a full under­ standing of virus-host interaction will lead to strategies useful for the prevention and control of HSV. The state of current progress with conventional vaccines is presented, as is a chapter on intracellular immunization. This latter novel approach to virus infections comes at approximately the bicentenary of Jenner's introduction of a successful conventional immunization strategy.

Editors and Affiliations

  • Department of Microbiology, College of Veterinary Medicine, University of Tennessee, Knoxville, USA

    Barry T. Rouse

Bibliographic Information

  • Book Title: Herpes Simplex Virus

  • Book Subtitle: Pathogenesis, Immunobiology and Control

  • Editors: Barry T. Rouse

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-77247-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 1992

  • Softcover ISBN: 978-3-642-77249-8Published: 15 November 2011

  • eBook ISBN: 978-3-642-77247-4Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: X, 179

  • Number of Illustrations: 2 b/w illustrations

  • Topics: Virology, Allergology, Immunology, Internal Medicine, Medical Microbiology

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