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  • Book
  • © 1992

Membrane Defenses Against Attack by Complement and Perforins

Editors:

  1. Charles J. Parker

    1. Department of Veterans Affairs Medical Center, University of Utah School of Medicine, Salt Lake City, USA

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Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 178)

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-vii
    PDF

  3. Decay Accelerating Factor (CD55)

    • A. Nicholson-Weller
    Pages 7-30

  4. Complement Receptor Type 1

    • G. D. Ross
    Pages 31-44

  5. Membrane Cofactor Protein

    • M. K. Liszewski, J. P. Atkinson
    Pages 45-60

  6. Membrane Inhibitor of Reactive Lysis

    • M. H. Holguin, C. J. Parker
    Pages 61-85

  7. Homologous Restriction Factor

    • L. S. Zalman
    Pages 87-99

  11. Paroxysmal Nocturnal Hemoglobinuria

    • W. F. Rosse
    Pages 163-173

  13. Back Matter

    Pages 185-190
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About this book

In this volume a comprehensive review of membrane proteins that regulate complement and perforin-mediated cytolysis is presented. A detailed analysisis provided of the biochemical, molecular, and functional features of these proteins; the glycosyl phosphatidylinositol linked proteins are covered, with emphasis placed on the functional importance of this type of membrane anchor. Further chapters include reviews of the effects of complement activation on cells that are metabolically active, and of the regulation of cell killing by cytotoxic lymphocytes, considering the similarities and disparities between the complement and perforin systems. The therapeutic use of recombinant CR1 for immune-mediated pathophysiological processes is discussed in a separate section.
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Keywords

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Editors and Affiliations

  • Department of Veterans Affairs Medical Center, University of Utah School of Medicine, Salt Lake City, USA

    Charles J. Parker

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Bibliographic Information

  • Book Title: Membrane Defenses Against Attack by Complement and Perforins

  • Editors: Charles J. Parker

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-77014-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 1992

  • Softcover ISBN: 978-3-642-77016-6Published: 16 December 2011

  • eBook ISBN: 978-3-642-77014-2Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: VIII, 188

  • Number of Illustrations: 5 b/w illustrations

  • Topics: Immunology, Biochemistry, general, Cell Biology

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Buy it now

eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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