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Genetic Approaches to Coronary Heart Disease and Hypertension

  • Conference proceedings
  • © 1991

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Table of contents (13 papers)

Keywords

About this book

Cardiovascular diseases are the principal cause of mortality in many developed countries and are increasing in importance in developing countries where communicable diseases are being brought under control. It is estimated that coronary heart disease (CRD) and cerebrovascular diseases are responsible for between 40-50% of all deaths. Righ blood pressure is common in all industrialized societies and contributes importantly to CRD. It is well known that genetic factors play an important role in the etiology and pathogenes es of cardiovascular diseases and contribute to an individual's susceptibility or resistance to the disease. The application of modern genetic techniques has resulted in the identification of polymorphie markers that are involved in the normal regulation and function of the cardiovascular system. Many of these may contribute to the individual differences in the risk for CRD and hypertension. It is now known that several risk factors or protective factors with respect to cardiovascular diseases are strongly influenced by genes, and it is now possible to identify individual genes contributing to cardiovascular risk. A large bank of genetic knowledge relevant to CRD and hypertension has become available during the past years. As a result, it is now believed that CRD, for example, could be a good model for a feasibility study to determine a way by which preventive measures can be applied.

Editors and Affiliations

  • Institute of Medical Genetics, UllevalHospital, University of Oslo, Oslo, Norway

    Kare Berg

  • World Health Organization, Geneva 27, Switzerland

    Victor Bulyzhenkov

  • Fondation IPSEN pour la Recherche, Thérapeutique, Paris Cedex, France

    Yves Christen

  • INSERM Unit 36, Collège de France, Paris, France

    Pierre Corvol

Bibliographic Information

  • Book Title: Genetic Approaches to Coronary Heart Disease and Hypertension

  • Editors: Kare Berg, Victor Bulyzhenkov, Yves Christen, Pierre Corvol

  • DOI: https://doi.org/10.1007/978-3-642-76891-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1991

  • Softcover ISBN: 978-3-642-76893-4Published: 21 December 2011

  • eBook ISBN: 978-3-642-76891-0Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XIV, 159

  • Number of Illustrations: 17 b/w illustrations

  • Topics: Cardiology, Human Genetics

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