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Basic and Clinical Research on Renal Cell Carcinoma

  • Conference proceedings
  • © 1992

Overview

Editors:
  1. Gerd Staehler

    1. Abteilung Urologie und Poliklinik Klinikum, Ruprecht-Karls-Universität, Heidelberg, Germany

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  2. Sigmund Pomer

    1. Abteilung Urologie und Poliklinik Klinikum, Ruprecht-Karls-Universität, Heidelberg, Germany

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Table of contents (21 papers)

  1. Front Matter

    Pages I-XII
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  2. Molecular and Cellular Basis of Renal Cell Carcinoma

    1. Front Matter

      Pages 1-1
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    2. Molecular Differential Pathology of Renal Cell Tumors

      • G. Kovacs
      Pages 3-8

    3. Pathobiology of Renal Carcinogenesis

      • P. Bannasch, H. Zerban
      Pages 9-26

    4. Molecular Analysis of DNA Sequences on Chromosome 3 in Patients with Renal Cell Carcinoma

      • H. Brauch, K. Tory, S. Hosoe, P. Anglard, M. Lerman, M. Linehan et al.
      Pages 27-34

  3. Cell Proliferation and Cellular Heterogeneity in Renal Cell Carcinoma

    1. Front Matter

      Pages 35-35
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    2. 31P NMR Spectroscopy of Human Tumor Cells In Vitro and In Vivo: Prospects for Applications to Renal Cell Carcinoma

      • W. E. Hull, A. C. Kuesel, S. Pomer
      Pages 37-48

    3. Conservative Surgery of Renal Tumors: Operative Technique, Complications, Results, DNA Cytometry

      • F. Steinbach, M. Stöckle, J. W. Thüroff, S. Störkel, S. W. Melchior, S. C. Müller et al.
      Pages 49-60

    4. Clinical Relevance of Proliferation Rates in Renal Cell Carcinoma

      • W. de Riese, E. P. Allhoff, C. G. Stief, R. Schlick, P. Anton, U. Jonas
      Pages 61-67

  4. Chemotherapy of Renal Cell Carcinoma

    1. Front Matter

      Pages 69-69
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    2. Cytotoxic Chemotherapy Phase II Trials Between 1983 and 1990 for Advanced Renal Cell Carcinoma

      • A. Yagoda
      Pages 71-78

    3. Modulation of Multidrug Resistance in Human Renal Cell Carcinomas

      • G. H. Mickisch, P. M. Alken
      Pages 79-88

    4. Transgenic Mice Carrying the Human MDR 1 Gene: Reliable In Vivo Probes to Examine Multidrug Resistance

      • G. H. Mickisch, M. M. Gottesman, I. Pastan
      Pages 89-100

    5. Adhesion Molecules and Their Possible Influence on Immune Surveillance

      • C. A. Schirren, H. Völpel, S. C. Meuer
      Pages 101-112

  5. Immunobiology of Renal Cell Carcinoma

    1. Front Matter

      Pages 113-113
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    2. Anti-Proliferative and Anti-Tumor Effect of α-Interferon in Renal Cell Carcinoma: Correlation with the Expression of a Kidney Associated Differentiation Glycoprotein

      • N. H. Bander, G. Gastl, D. M. Nanus, L. M. Pfeffer, C. L. Finstad, A. P. Albino
      Pages 115-120

    3. Prediction of Cytokine-Therapy on Basis of Class-I and Class-II MHC Antigen Induction

      • A. J. M. C. Beniers, W. P. Peelen, F. M. J. Debruyne, J. A. Schalken
      Pages 121-133

    4. Alien Gene Transfection and the Immune Response to Tumors

      • P. Frost
      Pages 134-141

    5. Active Specific Immunotherapy with Tumor Cells Expressing a Foreign Gene

      • H. K. Schackert, P. Frost
      Pages 142-147

    6. Novel Monoclonal Antibody 138H11 Against Human γ-Glutamyl-Transferase: Classification, Histogenesis and Immunoscintigraphy of Renal Tumors

      • P. Fischer, R. P. Baum, M. Tauber, W. Boeckmann, S. Störkel, S. Weier et al.
      Pages 148-155
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Keywords

About this book

Advanced Renal Cell Carcinoma (RCC) cannot be cured by surgery alone. Its resillience to irradiation and chemotherapy demands a new approach to the management of this disease. This book provides an overview of the scientific and clinical developments of RCC, and clarifies the fields ofimmunotherapy and immunobiology. The book contains a compilation of approaches that will enhance the effectiveness of the management of advancedRCC, even in the absence of definitive pre-clinical data. These require additional study and will stimulate the reassessment of preliminary results.Furthermore, preliminary results of already implemented clinical trials withbiological modifiers are presented. Of special interest are the current achievements in the field of immunotherapy using topically and subcutaneously low dosage combinations of cytokines. This concise volume will benefit those seeking a thorough review of the research and the clinical aspects of RCC simultaneously.

Editors and Affiliations

  • Abteilung Urologie und Poliklinik Klinikum, Ruprecht-Karls-Universität, Heidelberg, Germany

    Gerd Staehler, Sigmund Pomer

Bibliographic Information

  • Book Title: Basic and Clinical Research on Renal Cell Carcinoma

  • Editors: Gerd Staehler, Sigmund Pomer

  • DOI: https://doi.org/10.1007/978-3-642-76863-7

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1992

  • Softcover ISBN: 978-3-642-76865-1Published: 16 December 2011

  • eBook ISBN: 978-3-642-76863-7Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XII, 237

  • Topics: Urology, Oncology, Nephrology, Imaging / Radiology

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