Harderian Glands

1. Front Matter

   Pages I-XIV

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2. The Past, Present, and Future of the Harderian Gland

   • James Michael Olcese

   Pages 1-6

3. Comparative Anatomy of Mammalian Harderian Glands

   • Tatsuo Sakai

   Pages 7-23

4. Harderian Glands and Their Development in Laboratory Rats and Mice

   • Kazuhiko Shirama, Masami Hokano

   Pages 25-51

5. The Structure of the Harderian Gland of the Golden Hamster

   • A. P. Payne, J. McGadey, H. S. Johnston

   Pages 53-67

6. The Mammalian Harderian Gland: Ultrastructure, Sexual Dimorphism, and Its Regulation by Light and Steroids

   • Mathew J. Nadakavukaren

   Pages 69-90

7. The Harderian Gland of Amphibians and Reptiles

   • G. Chieffi, G. Chieffi Baccari, L. Di Matteo, M. d’Istria, C. Marmorino, S. Minucci et al.

   Pages 91-108

8. Morphology of the Harderian Gland in the Rabbit. A Short Review

   • Wolfgang Kühnel

   Pages 109-125

9. The Function of the Harderian Gland in the Mongolian Gerbil, Meriones unguiculatus

   • Delbert Thiessen

   Pages 127-140

10. Gonadal Hormones, Structure, and Porphyrin Synthesis in the Rodent Harderian Gland

    • A. P. Payne, R. C. Spike, M. R. Moore

    Pages 141-154

11. The Harderian Gland in Birds: Histology and Immunology

    • R. B. Burns

    Pages 155-163

12. Porphyrins and Their Possible Significance in Harderian Glands

    • Rosemary C. Spike, Anthony P. Payne, Michael R. Moore

    Pages 165-193

13. Lipids in Harderian Glands and Their Significance

    • Yousuke Seyama, Takeshi Kasama, Etsuko Yasugi, Sun-Hee Park, Kazutaka Kano

    Pages 195-217

14. Harderian Gland Indoles

    • Armando Menendez-Pelaez, Gerald R. Buzzell

    Pages 219-234

15. Harderian Gland Peptides

    • Susan M. Webb, Manuel Puig-Domingo, Mercè Viader, Eugenia Mato, Miguel-Angel Peinado

    Pages 235-243

16. Adrenergic Activity in the Male Rat Harderian Gland

    • Pedro Abreu, Guadalberto Hernández, Natalia Fajardo, Rafael Alonso

    Pages 245-254

17. The Interrelationship Between the Harderian Glands and the Neuroendocrine-Thyroid Axis in Rodents

    • Gerald R. Buzzell, Armando Menendez-Pelaez

    Pages 255-270

18. Type II 5′-Deiodinase in the Harderian Gland

    • M. K. Vaughan, J. M. Guerrero

    Pages 271-277

19. The Pineal and the Harderian Glands: Evidence for Mutual Interactions

    • Russel J. Reiter, Bruce A. Richardson

    Pages 279-295

20. The Harderian Gland as a Target for Steroid Hormone Action: Role and Characteristics of Intracellular Receptors

    • Felipe Vilchis, Bertha Chávez, Marco A. Cerbón, Gregorio Pérez-Palacios

    Pages 297-316

Harderian glands, first described by Jacob Harder in two species of deer in 1694, are large, intraorbital glands which, with but few exceptions, are found in all land vertebrates. Certainly, their relatively large size, their phylogenetic age, and persistent conservation in all groups as they emerged from an aqueous to an air/land environment lend strong support to the logical deduction that they probably play an important role in the physiological adaptation to terrestrial life. Yet, few biologists know even what or where these glands are. For a variety of reasons, the Harderian glands have not received the attention they deserve and, as a result, the published works available have been scarce and scattered throughout the world literature. The current situation is remarkably similar to that which existed in regard to the pineal gland prior to the mid-1960s, i. e. , scattered literature, unknown function, few investigators, and little interest. Yet, following a few key papers, interest in the pineal gland expanded and soon an explosive increase in the knowledge and understanding of the pineal gland took place and continues today. Will history repeat itself? Originally, a few of us discussed the desirability of an informal Symposium on the Harderian glands.

• Glands
• Hypophyse
• Porphyrin metabolism
• Porphyrinstoffwechsel
• biochemistry
• circulation
• classification
• development
• metabolism
• morphology
• osmoregulation
• reptiles
• thermoregulation
• tissue
• vertebrates

• Dept. of Endocrinology, Hospital de Sant Pau Autonomous University, Barcelona, Spain

  Susan M. Webb

• Dept. of Biology, Colgate University, Hamilton, USA

  Roger A. Hoffman

• Dept. of Endocrinology, Hospital Santa Creu de Sant Pau University Autonoma de Barcelona, Barcelona, Spain

  Manuel L. Puig-Domingo

• Dept. of Cellular & Structural Biology, The University of Texas Health Science Center, San Antonio, USA

  Russel J. Reiter

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