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DNA — Technology and Its Forensic Application

  • Book
  • © 1991

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Editors:
  1. G. Berghaus

    1. Institut für Rechtsmedizin, Universität Köln, Köln 30, Germany

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  2. B. Brinkmann

    1. Institut für Rechtsmedizin, Westfälische Wilhelms-Universität, Münster, Germany

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  3. C. Rittner

    1. Institut für Rechtsmedizin, Johannes-Gutenberg-Universität, Mainz, Germany

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  4. M. Staak

    1. Institut für Rechtsmedizin, Universität Köln, Köln 30, Germany

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Table of contents (33 chapters)

  1. Front Matter

    Pages I-XI
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  2. Review Lectures

    1. Front Matter

      Pages 1-1
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    2. Principles and Recent Advances in DNA Fingerprinting

      • A. J. Jeffreys, N. J. Royle, I. Patel, J. A. L. Armour, A. MacLeod, A. Collick et al.
      Pages 3-19

    3. DNA Fingerprinting as a Tool of Paternity Testing in Germany

      • C. Rittner, U. Schacker, P. M. Schneider
      Pages 20-32

    4. Genetic Typing of Biological Evidence Using the Polymerase Chain Reaction

      • G. F. Sensabaugh
      Pages 33-40

    5. A Critical Review of the Forensic Application of DNA Technology

      • B. Brinkmann, P. Wiegand, S. Rand
      Pages 41-49

    6. DNA Methylation: A Defense Mechanism Against the Expression of Foreign DNA?

      • W. Doerfler
      Pages 50-58

    7. Juristische Aspekte der forensischen DNA-Analyse

      • G. Kohlmann
      Pages 59-67

  3. PCR-Technology

    1. Front Matter

      Pages 69-69
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    2. Research Regarding the Polymerase Chain Reaction for Forensic Utility — HLA-DQα Locus and AMP-FLPs

      • B. Budowle, C. T. Comey, J. M. Jung, A. M. Giusti
      Pages 71-78

    3. DNA Typing Using PCR Amplified Fragments in the HLA Class I Region

      • J. Holtz, K. Schönborn-Sobolewski, S. Urmetz
      Pages 79-84

    4. PCR-Typing of the Human HLA-DQα Locus: Population Genetics and Application in Forensic Casework

      • P. M. Schneider, A. Veit, C. Rittner
      Pages 85-91

    5. DNA Amplification (PCR) of Several Hypervariable Loci in Disputed Paternity Cases

      • E. Trabetti, D. De Leo, P. Gasparini, P. F. Pignatti, M. Marigo
      Pages 92-95

    6. Amplification of a Highly Polymorphic VNTR Segment, Localized on the Ha-Ras Gene by PCR

      • H. Haas, M. Prinz, M. Staak, G. Berghaus
      Pages 96-100

  4. Methodology, Data Base

    1. Front Matter

      Pages 101-101
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    2. Reliability of Restriction Enzyme Digestions of Genomic DNA for the Generation of DNA Fingerprints

      • U. Schacker, T. Kaufmann, P. M. Schneider, C. Rittner
      Pages 103-108

    3. Concept for a More Precise Definition of the Polymorphism YNH24

      • C. Puers, S. Rand, B. Brinkmann
      Pages 109-115

    4. Evaluation of Variable Number of Tandem Repeat (VNTR) Alleles in Mother-Child Combinations

      • G. Holmlund, B. Lindblom
      Pages 116-120

    5. A Proposed Combination of Single Locus Probes for Multiple Rehybridization

      • P. Wiegand, S. Rand, B. Brinkmann
      Pages 121-127

    6. DNA-Profiles with HVR-Probes — Allele Frequencies of HinfI-RFLPs Using pHINS310, pMUC7 and pMR24/1 in a Population Sample from Hannover and Lower Saxony

      • T. Rothämel, W. Keil, H. D. Tröger
      Pages 128-133
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Keywords

About this book

All up-to-date aspects of DNA technology are discussed partly in review lectures but mostly in research articles in this volume: new methods, population statistics for different restriction fragment length polymorphisms (RFLP's), new developments dealing with the polymerase chain reaction (PCR), biostatistical aspects of single locus and multi locus profiles as well as examples of practical applications in paternity testing and forensic stain analysis. Contributors to this volume include most internationally acclaimed researchers in this field. Besides facts that are primarily of interest to forensic scientists, immunohaematologists and human geneticists should also find some aspects for their research.

Editors and Affiliations

  • Institut für Rechtsmedizin, Universität Köln, Köln 30, Germany

    G. Berghaus, M. Staak

  • Institut für Rechtsmedizin, Westfälische Wilhelms-Universität, Münster, Germany

    B. Brinkmann

  • Institut für Rechtsmedizin, Johannes-Gutenberg-Universität, Mainz, Germany

    C. Rittner

Bibliographic Information

  • Book Title: DNA — Technology and Its Forensic Application

  • Editors: G. Berghaus, B. Brinkmann, C. Rittner, M. Staak

  • DOI: https://doi.org/10.1007/978-3-642-76632-9

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1991

  • Softcover ISBN: 978-3-540-54035-9Published: 16 September 1991

  • eBook ISBN: 978-3-642-76632-9Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XI, 225

  • Number of Illustrations: 55 b/w illustrations

  • Topics: Forensic Medicine, Human Genetics, Hematology, Statistics for Life Sciences, Medicine, Health Sciences

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