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Acute Leukemias

Pharmacokinetics and Management of Relapsed and Refractory Disease

  • Conference proceedings
  • © 1992

Overview

Editors:
  1. W. Hiddemann

    1. Department of Internal Medicine, University of Münster, Münster, Federal Republic of Germany

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  2. T. Büchner

    1. Department of Internal Medicine, University of Münster, Münster, Federal Republic of Germany

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  3. B. Wörmann

    1. Department of Internal Medicine, University of Münster, Münster, Federal Republic of Germany

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  4. W. Plunkett

    1. M. D. Anderson Cancer Center, University of Texas, Houston, USA

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  5. M. Keating

    1. M. D. Anderson Cancer Center, University of Texas, Houston, USA

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  6. M. Andreeff

    1. M. D. Anderson Cancer Center, University of Texas, Houston, USA

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Part of the book series: Haematology and Blood Transfusion Hämatologie und Bluttransfusion (HAEMATOLOGY, volume 34)

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Table of contents (113 papers)

  1. Front Matter

    Pages I-XXVI
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  2. Drug Resistance in Leukemia

    1. Front Matter

      Pages 1-1
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    2. Multidrug Resistance and Its Circumvention in Acute Leukemia

      • A. F. List, C. M. Spier, W. S. Dalton
      Pages 3-10

    3. The Role of DNA Topoisomerase II in Multidrug Resistance in Human Leukemia

      • W. T. Beck, T. Funabiki, M. K. Danks
      Pages 11-15

    4. Development of Sensitive Assays to Detect Antifolate Resistance in Leukemia Blasts

      • T. Trippett, J. T. Lin, Y. Elisseyeff, M. Wachter, S. Schlemmer, B. Schweitzer et al.
      Pages 16-22

    5. Sequential Analysis of P-Glycoprotein Expression in Childhood Acute Lymphoblastic Leukemia

      • D. Kingreen, C. Sperling, M. Notter, C. Schmidt, H. Diddens, H. Riehm et al.
      Pages 23-28

    6. Expression of the MDR1 Gene and Treatment Outcome in Acute Nonlymphocytic Leukemia

      • R. Pirker, J. Wallner, K. Geissler, P. Bettelheim, W. Linkesch, K. Lechner
      Pages 29-32

    7. Multidrug Resistance Proteins and their Functional Modulation in Human Leukemias as Analyzed by Flow Cytometry

      • L. Van Hove, K. Van Acker, M. Boogaerts
      Pages 33-39

    8. Reversal of Multidrug Resistance with a New Calcium/Calmodulin Antagonist

      • E. Roller, B. Benz, M. Eichelbaum, V. Gekeler, K. Häußermann, B. Klumpp et al.
      Pages 40-43

    9. Characterization of Human Leukemic HL-60 Sublines as a Model for Primary and Secondary Resistance Against Cytostatics

      • E. Gieseler, F. Boege, R. Erttmann, H.-P. Tony, H. Biersack, B. Spohn et al.
      Pages 44-48

    10. Conserved Cytotoxic Activity of Aclacinomycin A in Multifactorial Multidrug Resistance

      • R. Erttmann, A. Boetefür, K. D. Erttmann, F. Gieseler, G. Looft, M. Münchmeyer et al.
      Pages 49-55

    11. Cytostatic Drug Resistance and Differentiation in Friend Erythroleukemia Cells

      • C. A. Schmidt, A. Schäfer, F. Lorenz, H. Oettle, F. F. Wilborn, D. Huhn et al.
      Pages 56-59

    12. On the Role of Aldehyde Dehydrogenase in a Cyclophosphamide-Resistant Variant of Brown Norway Rat Acute Myelocytic Leukemia

      • C. J. de Groot, A. C. M. Martens, A. Hagenbeek
      Pages 60-64

    13. SAENTA-fluoresceins: New Flow Cytometry Reagents for Assessing Transport of Nucleoside Drugs in Acute Leukemia

      • J. S. Wiley, G. P. Jamieson, A. M. Brocklebank, M. B. Snook, W. H. Sawyer, P. M. Dennington et al.
      Pages 65-71

  3. Hematopoietic Growth Factors in Leukemia Therapy

    1. Front Matter

      Pages 73-73
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    2. Human Stem Cell Factor: Biological Effects and Receptor Expression on Myeloid Leukemia Cells

      • T. Pietsch, U. Kyas, K. Zsebo, K. Welte
      Pages 75-80

    3. Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor Following Chemotherapy in Patients with High-Risk AML

      • T. Büchner, W. Hiddemann, M. Koenigsmann, M. Zühlsdorf, B. Wörmann, A. Boeckmann et al.
      Pages 81-96

    4. Use of Granulocyte-Macrophage Colony-Stimulating Factor Prior to Chemotherapy of Newly Diagnosed AML

      • E. Estey, H. Kantarjian, S. O’Brien, M. Beran, K. McCredie, C. Koller et al.
      Pages 97-100

    5. G-CSF after Intensive Induction Chemotherapy in Refractory Acute Leukemia and Bone Marrow Transplantation in Myeloid Leukemia

      • R. Ohno, T. Masaoka, S. Asano, F. Takaku
      Pages 101-107

    6. Cytokinetic Resistance in Acute Leukemia: Recombinant Human Granulocyte Colony-Stimulating Factor, Granulocyte Macrophage Colony-Stimulating Factor, Interleukin-3 and Stem Cell Factor Effects In Vitro and Clinical Trials with Granulocyte Macrophage Colony-Stimulating Factor

      • M. Andreeff, A. Tafuri, P. Bettelheim, P. Valent, E. Estey, R. Lemoli et al.
      Pages 108-117
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Keywords

Editors and Affiliations

  • Department of Internal Medicine, University of Münster, Münster, Federal Republic of Germany

    W. Hiddemann, T. Büchner, B. Wörmann

  • M. D. Anderson Cancer Center, University of Texas, Houston, USA

    W. Plunkett, M. Keating, M. Andreeff

Bibliographic Information

  • Book Title: Acute Leukemias

  • Book Subtitle: Pharmacokinetics and Management of Relapsed and Refractory Disease

  • Editors: W. Hiddemann, T. Büchner, B. Wörmann, W. Plunkett, M. Keating, M. Andreeff

  • Series Title: Haematology and Blood Transfusion Hämatologie und Bluttransfusion

  • DOI: https://doi.org/10.1007/978-3-642-76591-9

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1992

  • Softcover ISBN: 978-3-540-53949-0Published: 25 February 1992

  • eBook ISBN: 978-3-642-76591-9Published: 06 December 2012

  • Series ISSN: 0440-0607

  • Edition Number: 1

  • Number of Pages: XXVI, 670

  • Number of Illustrations: 69 b/w illustrations

  • Topics: Hematology, Oncology, Pharmacology/Toxicology

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