Limb Salvage

1. Front Matter

   Pages i-xxxi

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2. Allografts

   1. Front Matter

      Pages 1-1

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   2. The Clinical Use of Frozen Cadaveric Allografts in the Management of Bone Tumors: An Overview

      • H. J. Mankin

      Pages 3-7

   3. Morphological Investigations of Osteochondral Allografts

      • C. Delloye, C. Savineau-Lalanne, P. De Nayer, M. F. Harmand

      Pages 9-15

   4. Isotope Metabolism and Biochemistry of Massive Osteoarticular Allografts

      • A. J. Aho, A. Ahonen, T. Ekfors, H. T. Aro, T. Helelä, J. Niinikoski

      Pages 17-23

   5. The Development of a Size and Shape Matching Index for Osteochondral Allografts

      • M. L. Samson, K.-N. An, M. G. Rock, R. A. Robb, E. Y. S. Chao

      Pages 25-31

   6. Radiation Sterilized Bone Allografts: Banking Procedure and Clinical Results After 150 Massive Allografts

      • B. Loty, J. P. Courpied, B. Tomeno, M. Postel, M. Forest, R. Abelanet

      Pages 33-39

   7. Allograft Replacement in Aggressive and Malignant Bone Tumors: A Long-Term Study

      • A. Alho, A. J. Aho, E. O. Karaharju

      Pages 41-45

   8. Massive Intercalary Allografts in the Reconstruction of Segmental Bone Defects

      • R. M. Bloem, K.-C. Chan, W. W. Tomford, H. J. Mankin

      Pages 47-55

   9. Osteoarticular Allograft Reconstruction of the Proximal Humerus Following Limb-Sparing Surgery

      • T. Heare, J. B. Duke, D. S. Springfield, R. Vander Griend

      Pages 57-65

   10. Allografts in Bone Tumor Surgery: Short-Term Results

       • G. Follerås, I. Bjerkreim

       Pages 67-73

   11. Technical Aspects and Surgical Complications of Segmental Allografts Following Segmental Resections of Malignant Bone Tumors

       • H. A. Finn, M. A. Simon

       Pages 75-87

   12. Complications of Fresh Frozen Bone Allografts for Tumor Reconstruction and Their Management

       • S. Gitelis, P. Piasecki, K. Luke

       Pages 89-94

   13. Segmental Allograft Reconstruction Concomitant with Neoadjuvant Chemotherapy

       • A. Czitrom, R. Capanna, D. Donati, G. Bacci, M. Campanacci

       Pages 95-99

   14. Evaluation of Allograft Fixation

       • R. Vander Griend, C. Sollaci, G. Miller

       Pages 101-105

   15. Chemotherapy Effect on the Clinical Results of Allograft Transplantation in the Treatment of Malignant Bone Tumors

       • K. M. Yaw, M. C. Gebhardt, H. J. Mankin

       Pages 107-115

   16. Bone Union in Allografts: Chemotherapy Considerations

       • N. Delepine, G. Delepine, P. Hernigou, D. Goutallier

       Pages 117-119

   17. Treatment of Complications in Intercalary and Terminal Allografts

       • P. Hernigou, G. Delepine, P. Romano, D. Goutallier

       Pages 121-124

   18. Complications in Hemipelvic Resection/Allograft Reconstruction for Bone Sarcomas: Are They Prohibitive to Limb Salvage?

       • M. J. Joyce, J. T. Makley

       Pages 125-138

3. Innovative Materials and Devices

   1. Front Matter

      Pages 139-139

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An international group ofresearchers has met every 2 years since 1981 to examine the progress made in limb salvage techniques and the perspectives of this field of surgery. In 1989 the Fifth International Symposium On Limb Salvage (ISOLS) was held in Saint Malo and was attended by more than 300 participants from 34 different countries. The 105 papers presented, grouped under eleven main headings, have been included in this book. Limb salvage has indeed progressed in the years since the first symposium. Initially it essentially concerned tumours and the main aim was to salvage the diseased limb through non-mutilating surgery without jeopardizing the patient's prospects of survival. Now, with a confirmed high rate of 5-year disease-free survival, new goals can be set: improvement of the functional results and of the survival of our reconstructions. How can this be achieved: - By favouring muscle reattachment on the prosthesis, for instance through the use of a bone allograft-sleeved composite prosthesis? - By improving the survival of the arthroplasty through the develop­ ment of a more biological fixation of its stems? - By limiting the side effects of the necessary adjuvant treatments on the function of the allograft as well as on the fixation of the prosthesis? In addition, limb salvage procedures now concern not only primary tumours (and metastases, which must be treated using the same osteosynthetic and prosthetic techniques), but also reconstructive orthopaedic surgery as a whole.

• CT
• Magnetic Resonance Imaging (MRI
• bone
• bone metastases
• chemotherapy
• computed tomography (CT)
• fixation
• imaging
• imaging techniques
• magnetic resonance imaging (MRI)
• metastasis
• metastatic disease
• oncology
• surgery
• tumor

• Orthopaedic Department, University of Rennes Centre Hospitalier Hôpital Sud, Rennes, France

  F. Langlais

• Orthopaedic Clinic, Hôpital Cochin, Paris, France

  B. Tomeno

Policies and ethics