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Reaction Patterns of the Lymph Node

Part 2 Reactions Associated with Neoplasia and Immune Deficient States

  • Book
  • © 1991

Overview

Editors:
  1. E. Grundmann

    1. Gerhard-Domagk-Institut für Pathologie, Universität Münster, Münster, Federal of Republic of Germany

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  2. E. Vollmer

    1. Gerhard-Domagk-Institut für Pathologie, Universität Münster, Münster, Federal of Republic of Germany

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Part of the book series: Current Topics in Pathology (CT PATHOLOGY, volume 84/2)

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Table of contents (6 chapters)

  1. Front Matter

    Pages I-IX
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  2. Reaction Patterns of Lymph Nodes in the Development and Spread of Cancer

    • E. Vollmer, V. Krieg, F. Shimamoto, E. Grundmann
    Pages 1-34

  3. Patterns of Fibronectin Induction in Lymph Nodes Affected by Metastatic Growth of Adenocarcinomas

    • N. Beck, D. Lorke, P. Möller
    Pages 35-47

  4. Macrophages/Reticulum Cells in Early and Late Phases of Lymphogenous Metastasis

    • E. Vollmer, F. Shimamoto, V. Krieg, E. Grundmann
    Pages 49-79

  5. Primary Immunodeficiency Syndromes and Their Manifestations in Lymph Nodes

    • H. Cottier, R. Kraft, F. Meister
    Pages 81-155

  6. Immunological Dysregulation of Lymph Nodes in AIDS Patients

    • G. R. F. Krueger, D. V. Ablashi, P. Lusso, S. F. Josephs
    Pages 157-188

  7. Lymph Node Reaction Patterns in Patients with AIDS or AIDS-Related Complex

    • J. Diebold, J. Audouin, A. Le Tourneau, S. Prevot, G. Szekeres
    Pages 189-221

  8. Back Matter

    Pages 223-232
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Keywords

About this book

This second volume reports on the reaction patterns of lymph nodes in neoplastic and immunodeficient diseases. Based on the contents of volume 1, it presents a detailed survey of lymph node structures and their cellular components under these conditions. The patterns of nodal reactions to the development and spread of cancer have recently been investigated and discussed by several authors. Here, the immediate interactions between tumor tissue and the regional nodes have been assessed in experimental models and in human material. Using modern morphological methods such as im­ munohistochemistry on the light and electron microscopic level, new insights have been gained into the stepwise process of lymphogenous metastasis. Macrophages/reticulum cells were found to playa signifi­ cant role in this process, which is duly emphasized. Based on appro­ priate animal models, one chapter focuses on various subtypes of these cellular elements and their role in the two separate phases of tumor spread and the development of true metastases. The induction of fibronectin in lymph nodes is effected by tumor cells forming a special part of the extracellular matrix. The multifunctional fibronec­ tin molecule serves as a mediator between tumor cells and fibroblasts, furthering the formation of tumor stroma. This volume also contains a comprehensive survey of primary im­ munodeficiency syndromes and their nodal manifestations, reference being made to the most recent immunological knowledge.

Editors and Affiliations

  • Gerhard-Domagk-Institut für Pathologie, Universität Münster, Münster, Federal of Republic of Germany

    E. Grundmann, E. Vollmer

Bibliographic Information

  • Book Title: Reaction Patterns of the Lymph Node

  • Book Subtitle: Part 2 Reactions Associated with Neoplasia and Immune Deficient States

  • Editors: E. Grundmann, E. Vollmer

  • Series Title: Current Topics in Pathology

  • DOI: https://doi.org/10.1007/978-3-642-75522-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1991

  • Softcover ISBN: 978-3-642-75524-8Published: 13 December 2011

  • eBook ISBN: 978-3-642-75522-4Published: 06 December 2012

  • Series ISSN: 0070-2188

  • Edition Number: 1

  • Number of Pages: IX, 225

  • Number of Illustrations: 68 b/w illustrations

  • Topics: Pathology, Hematology, Allergology, Immunology, Oncology

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