Onychomycoses

1. Front Matter

   Pages I-X

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2. Epidemiology and Pathology of Onychomycoses

   • E. Haneke

   Pages 1-11

3. The Treatment of Onychomycosis in Clinical Practice

   • C. W. Meisel

   Pages 12-28

4. An Alternative Treatment Concept in the Onychomycoses

   • I. Effendy, H. Kolczak

   Pages 29-44

5. Oral Treatment of the Onychomycoses

   • H. C. Korting

   Pages 45-56

6. Possibilities and Limitations in the Recording of the Onychomycoses During Treatment

   • D. Reinel

   Pages 57-64

7. Keratinolytic Agents in Dermatology

   • G. Stüttgen

   Pages 65-75

8. Problems of Compliance in Patients with Onychomycoses

   • W. Meinhof

   Pages 76-80

9. Experience with Bifonazole/Urea in Germany

   • K. S. Nolting

   Pages 81-86

10. Hospital Experience with Bifonazole/Urea

    • W.-I. Worret

    Pages 87-93

11. Clinical Experience with Bifonazole/Urea

    • Th.-M. Ernst, W. Hopfenmüller

    Pages 94-101

12. Topical Treatment of Onychomycoses with Bifonazole-Urea Ointment

    • S. Stettendorf

    Pages 102-107

13. Postface

    • H. C. Korting

    Pages 109-110

14. Back Matter

    Pages 111-113

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The human nail is formed from variably keratinized epithelial structures. The part of the nail organ which is the actual nail plate constitutes the end-product of keratinized cells produced by the matrix. The matrix cells lose their nuclei, become strati­ fied and keratinized, and are added to the firm nail plate al­ ready present. It is usually transparent or translucent, smooth and keratinous in structure, pushed forward by the keratin layer of the nail bed and growing out distally as a free edge over the finger/toe-tip. The transparent nail reveals the pink-coloured nail bed. Usually, a white half-moon shaped lunula is visible, extending under the proximal nail fold. The nail plate consti­ tutes a buttress to pressure. The rate of nail growth is greatest in the second and third decades oflife and declines slightly later. Increased nail growth may be noted during the summer and decreased growth in winter, in evident dependence on the peripheral circulation. Although the nail is not the primary site of attraction at a fleeting glance from others, changes in the nails are quite striking at a second look, and modern freedom of behavior means that changes in the toenails soon become very obvious, especially in women.

• Bifonazol
• Dermatophytose
• Onychomykose
• chemische Nagelablösung
• epidemiology

• Klinik und Poliklinik für Hautkrankheiten, Allgemeine Dermatologie und Venerologie, Universität Münster, Münster, Germany

  Siegfried Nolting

• Dermatologische Klinik und Poliklinik der Ludwig-Maximilians-Universität München, München 2, Germany

  Hans Christian Korting

Policies and ethics