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Retrovirus Infections of the Nervous System

Current and Future Perspectives

  • Conference proceedings
  • © 1990

Overview

Editors:
  1. Michael B. A. Oldstone

    1. Dept. of Neuropharmacology, Scripps Clinic and Research Foundation, La Jolla, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Hilary Koprowski

    1. The Wistar Institute, Philadelphia, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 160)

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Table of contents (10 papers)

  1. Front Matter

    Pages I-IX
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  2. Animal Retrovirus Infections of the Nervous System

    1. Front Matter

      Pages 1-1
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    2. Genetic Resistance to a Retroviral Neurologic Disease in Wild Mice

      • M. B. Gardner
      Pages 3-10

    3. Wild Mouse Retrovirus: Pathogenesis

      • J. L. Portis
      Pages 11-27

    4. Moloney Murine Leukemia Virus Temperature-Sensitive Mutants: A Model for Retrovirus-Induced Neurologic Disorders

      • P. K. Y. Wong
      Pages 29-60

    5. Caprine Arthritis Encephalitis Lentivirus Transmission and Disease

      • T. C. McGuire, K. I. O’Rourke, D. P. Knowles, W. P. Cheevers
      Pages 61-75

    6. Retroviral Infections of the CNS of Nonhuman Primates

      • A. A. Lackner, L. J. Lowenstine, P. A. Marx
      Pages 77-96

  3. Human Retrovirus Infections of the Nervous System

    1. Front Matter

      Pages 97-97
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    2. Human T-Cell Leukemia Virus Type 1 Infections of the Nervous System

      1. Neurological Disorders Associated with HTLV-1
        • D. E. McFarlin, H. Koprowski
        Pages 99-119
      2. An HTLV-I Transgenic Mouse Model: Role of the Tax Gene in Pathogenesis in Multiple Organ Systems
        • M. I. Nerenberg
        Pages 121-128

    3. Human Immunodeficiency Virus Infections of the Nervous System

      1. Using Synthetic Peptide Reagents to Distinguish Infections Caused by Different HIV Strains
        • J. W. Gnann Jr., M. B. A. Oldstone
        Pages 131-143
      2. Human Immunodeficiency Virus Infection of the CNS: Characterization of “Neurotropic” Strains
        • C. Cheng-Mayer, J. A. Levy
        Pages 145-156
      3. Human Immunodeficiency Virus: Infection of the Nervous System
        • C. A. Wiley, J. A. Nelson
        Pages 157-172

  4. Back Matter

    Pages 173-178
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Keywords

About this book

Although retroviruses have long been associated with a variety of animal diseases, active research in the field of human retroviruses dates from the discovery of human immunodefici­ ency virus (HIV) in association with acquired immunodefici­ ency syndrome (AIDS). The enormous research efforts in this field have been directed toward understanding the nature of the virus and toward its elimination through preventive vaccin­ ation and the cure of the disease. Human T-cell leukemia virus (HTLV-l) was the first member of the human retrovirus family to be discovered. It was implicated as the cause of adult T-cell leukemia (ATL) even before the association of HIV and AIDS was established. Research on HTL V -1 has, however, been lagging behind that of HIV because of the importance of AIDS. Today HTLV-1 and possibly closely related HTLV-2 are associated with a variety of human neurologic diseases, and research activities in this field may show that human retroviruses can cause a variety of human diseases in addition to those affecting the nervous system. Papers in this volume attempt to acquaint the reader with the present state of research into retrovirus infection and related diseases of the nervous system.

Editors and Affiliations

  • Dept. of Neuropharmacology, Scripps Clinic and Research Foundation, La Jolla, USA

    Michael B. A. Oldstone

  • The Wistar Institute, Philadelphia, USA

    Hilary Koprowski

Bibliographic Information

  • Book Title: Retrovirus Infections of the Nervous System

  • Book Subtitle: Current and Future Perspectives

  • Editors: Michael B. A. Oldstone, Hilary Koprowski

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-75267-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 1990

  • Softcover ISBN: 978-3-642-75269-8Published: 03 December 2011

  • eBook ISBN: 978-3-642-75267-4Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: IX, 176

  • Number of Illustrations: 8 b/w illustrations

  • Topics: Virology, Allergology, Immunology, Internal Medicine, Neurology, Oncology

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