Molecular Mechanisms of Hormone Action

1. Front Matter

   Pages I-XII

   PDF

2. Part 1

   1. Front Matter

      Pages 1-1

      PDF

   2. Mode of Action of Steroid Hormones: A Historical Review

      • P. Karlson

      Pages 3-11

   3. Interaction of Steroid Hormone Receptors with DNA

      • M. Beato, U. Brüggemeier, G. Chalepakis, B. Gross, B. Piña, M. Schauer et al.

      Pages 12-20

   4. Clustered Arrangement and Interaction of Steroid Hormone Receptors with Other Transcription Factors

      • R. Renkawitz, R. Schüle, C. Kaltschmidt, C. Baniahmad, A. Baniahmad, J. Altschmied et al.

      Pages 21-28

   5. Chromatin Template Remodeling and Steroid Receptor Transactivation of MMTV

      • G. L. Hager

      Pages 29-34

   6. Hormone-Dependent Transcriptional Activation by Thyroid Hormone Receptors: Functional Homology with Steroid Hormone Receptors

      • S. M. Hollenberg, C. C. Thompson, R. M. Evans

      Pages 35-43

   7. Subunit Structure of the Glucocorticoid Receptor

      • U. Gehring, M. Rexin, W. Busch, B. Segnitz, G. Zink

      Pages 44-52

   8. Modulation of Glucocorticoid Hormone Action by Oncogenes and Peptide Hormones

      • B. Groner, W. Höck, W. Doppler, R. Ball

      Pages 53-60

   9. Studies on the Regulation of Glycogen and Lipid Metabolism by Insulin and Growth Factors: The Involvement of Receptor Tyrosine Kinase Activation and Casein Kinase II

      • T. A. J. Haystead, E. G. Krebs

      Pages 61-71

3. Part 2

   1. Front Matter

      Pages 73-73

      PDF

   2. Genes Coding for G Proteins in Mammalian and Yeast Cells

      • Y. Kaziro

      Pages 75-84

   3. The ras Oncogene Protein

      • M. S. Marshall, M. D. Schaber, U. S. Vogel, W. S. Hill, A. S. Ng, E. M. Scolnick et al.

      Pages 85-91

   4. Molecular Mechanisms of G-Protein Activation

      • K. H. Jakobs, P. Gierschik, G. Hilf, C. Reithmann, D. Sidiropoulos, T. Wieland

      Pages 92-99

   5. Interaction of Transducin with Retinal cGMP Phosphodiesterase

      • Ph. Deterre, M. Chabre

      Pages 100-107

   6. Phosphoinositide Metabolism and Visual Signal Transduction

      • Z. Selinger, B. Minke

      Pages 108-115

   7. Hormonal Regulation of Phospholipases

      • J. H. Exton

      Pages 116-123

4. Part 3

   1. Front Matter

      Pages 125-125

      PDF

   2. Regulation of Ion Channels

      • H. Reuter

      Pages 126-131

   3. The Structure of the Skeletal and Nonskeletal Muscle Calcium Channel

      • F. Hofmann, P. Ruth, T. Schneider, J. Felbel, S. Regulla, M. Biel et al.

      Pages 132-138

Recent years have seen tremendous progress in the field of hormone action and consequent signal transduction. The 40th Colloquium Mosbach was devoted to the discussion of results concerning the molecular process of hormone action, especially the processes following hormone binding to the corresponding receptors. Structural and functional aspects of steroid hormone receptors as well as ion-channel-coupled and enzyme-linked receptors were treated in detail. Particular interest focussed on the latest results concerning transcriptional control, protein phosphorylation, the role of G-Proteins, oncogene proteins, involvement of phospholipases and the regulation of ion channels.

• Activation
• Calcium
• DNA
• G proteins
• Glycogen
• Lipid
• glucocorticoid
• hormone receptors
• insulin
• metabolism
• molecular mechanisms
• proteins
• regulation
• signal transduction
• transcription

• Institut für Biologische Chemie, Universität Heidelberg, Heidelberg, Germany

  Ulrich Gehring

• Institut für Physiologische Chemie, Universität Würzburg, Würzburg, Germany

  Ernst J. M. Helmreich

• Institut für Pharmakologie, Freie Universität Berlin, Berlin 33, Germany

  Günter Schultz

Policies and ethics