Growth Factors, Differentiation Factors, and Cytokines

1. Front Matter

   Pages I-XVII

   PDF

2. Peptide Growth Factors

   1. Front Matter

      Pages 1-1

      PDF

   2. Growth Factor Receptors: The Epidermal Growth Factor Receptor as a Model

      • K. C. Oberg, A. Brown, G. Carpenter

      Pages 3-17

   3. Epidermal Growth Factor: Biology and Properties of its Gene and Protein Precursor

      • B. Mroczkowski, R. Ball

      Pages 18-30

   4. Platelet-Derived Growth Factor: Formation and Biological Activities

      • A. J. R. Habenicht, P. Salbach, C. Blattner, U. Janßen-Timmen

      Pages 31-41

   5. Basic Fibroblast Growth Factor: Properties and Clinical Implications

      • L. Schweigerer

      Pages 42-55

   6. Transforming Growth Factor-β

      • J. Pfeilschifter

      Pages 56-64

   7. Distinctive Features of Nerve Growth Factor: Structure, and Function

      • M. V. Chao

      Pages 65-81

3. Hematopoetic Growth and Differentiation Factors

   1. Front Matter

      Pages 83-83

      PDF

   2. Interleukin 1

      • R. Schindler, C. A. Dinarello

      Pages 85-102

   3. Interleukin 2

      • B. Schwinzer, K. Resch

      Pages 103-114

   4. Interleukin 3: A Multilineage Hematopoietic Growth Factor

      • C. Stocking, W. Ostertag

      Pages 115-128

   5. Multiple Functions of Interleukin 4 and its Role in Immune Regulation

      • T. R. Mosmann, A. Zlotnik

      Pages 129-146

   6. Interleukin 5 as a Hematopoietic Cell Growth and Differentiation Factor

      • K. Takatsu, A. Tominaga

      Pages 147-162

   7. Interleukin 6

      • J. Van Snick, R. P. Nordan

      Pages 163-176

   8. The Hemopoietic Growth Factor, Granulocyte-Macrophage Colony Stimulating Factor

      • N. M. Gough

      Pages 177-187

   9. Colony Stimulating Factor-1

      • M. Baccarini, E. R. Stanley

      Pages 188-200

   10. Granulocyte Colony-Stimulating Factor

       • K. Welte, E. Platzer

       Pages 201-214

   11. Chicken Myelomonocytic Growth Factor

       • A. Leutz, T. Graf

       Pages 215-231

   12. Experimental and Clinical Evaluation of Erythropoietin

       • W. Oster, F. Herrmann, A. Lindemann, R. Mertelsmann

       Pages 232-242

Leading international experts contribute to this selection of reviews covering the merging fields of growth factors, differentiation factors, and cytokines. These appear to play fundamental roles in a wide variety of physiological and pathophysiological processes that include the regulation of growth in normal and malignant cells, embryogenesis, the immune response, wound healing, inflammation, and atherogenesis. The major aspects of recent research and development are discussed, providing an important update in this pioneering field.

• cytokines
• differentiation factors
• growth factors
• mitogenesis
• mitogenic signalling
• regulation

• Department of Internal Medicine Division of Endocrinology and Metabolism, University of Heidelberg, Heidelberg, Germany

  Andreas Habenicht

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