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Drug Research and Drug Development in the 21st Century

Science and Ethics

  • Conference proceedings
  • © 1989

Overview

Editors:
  1. H.-P. Wolff

    1. Wissenschaftlicher Beirat der Bundesärztekammer, Maria Alm/Hinterthal, Austria

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  2. A. Fleckenstein

    1. Physiologisches Institut, Universität Freiburg, Freiburg, Federal Republic of Germany

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  3. E. O. Philipp

    1. PH-Forschungszentrum, ZPM/Projektmanager, Bayer AG, Wuppertal, Federal Republic of Germany

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Part of the book series: Bayer AG Centenary Symposium (BAYER)

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Table of contents (27 papers)

  1. Front Matter

    Pages I-XII
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  2. History and Philosophy of Bayer Pharmaceutical Research

    1. History and Philosophy of Bayer Pharmaceutical Research

      • W.-D. Busse
      Pages 1-8

  3. Science, Responsibility, and Society

    1. Science, Responsibility, and Society

      • K. Heilmann
      Pages 9-15

  4. Opening Remarks

    1. Opening Remarks

      • A. Fleckenstein
      Pages 16-18

  5. Message of Greeting

    1. Message of Greeting

      • R. Süßmuth
      Pages 19-19

  6. Unresolved Problems of Chronic Diseases

    1. Front Matter

      Pages 21-21
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    2. Demographic and Epidemiologic Trends Today

      • R. Doll
      Pages 23-33

    3. Atherosclerosis and Coronary Heart Disease

      • G. Schettler, A. J. R. Habenicht
      Pages 34-42

    4. Rheumatoid Arthritis: A Model of Chronic Inflammation

      • B. C. Gilliland
      Pages 43-52

    5. Alzheimer’s Disease

      • S. Corkin
      Pages 53-61

    6. Obstructive Lung Disease

      • H. Herzog
      Pages 62-89

    7. Biological Approaches to Cancer Therapy

      • H. F. Oettgen
      Pages 90-104

    8. Challenges and Obstacles in Clinical Evaluations of Therapy

      1. Problems, Pitfalls, and Opportunities in Long-term Randomized Trials
        • A. R. Feinstein
        Pages 105-116
      2. The Impact of Clinical Trials on Clinical Practice
        • C. D. Furberg
        Pages 117-122

  7. Back Matter

    Pages 123-138
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  8. Advanced Technologies, Scientific Achievements

    1. Front Matter

      Pages 139-139
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    2. Receptors and Messengers

      1. Low Density Lipoproteins and Hypercholesterolemia
        • G. Assmann, H. Funke, G. Schmitz
        Pages 141-161
      2. Leukotrienes in Airways and Blood Vessels
        • P. J. Piper
        Pages 162-171

    3. Drug Design

      1. Opening Remarks
        • E. Mutschler
        Pages 172-172
      2. Thoughts About Gene Regulation and Mammalian Development
        • J. E. Darnell Jr.
        Pages 173-182
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Keywords

About this book

Distinguished scientists and members of the medical profession discuss the research and development of safe and suitable drugs for the long-term treatment of chronic diseases. The book provides an up-to-date survey on new insights and technologies - as well as ethical considerations - , since traditional means and methods of drug research and drug development may no longer suffice to meet the challenges of the next century.

Editors and Affiliations

  • Wissenschaftlicher Beirat der Bundesärztekammer, Maria Alm/Hinterthal, Austria

    H.-P. Wolff

  • Physiologisches Institut, Universität Freiburg, Freiburg, Federal Republic of Germany

    A. Fleckenstein

  • PH-Forschungszentrum, ZPM/Projektmanager, Bayer AG, Wuppertal, Federal Republic of Germany

    E. O. Philipp

Bibliographic Information

  • Book Title: Drug Research and Drug Development in the 21st Century

  • Book Subtitle: Science and Ethics

  • Editors: H.-P. Wolff, A. Fleckenstein, E. O. Philipp

  • Series Title: Bayer AG Centenary Symposium

  • DOI: https://doi.org/10.1007/978-3-642-74615-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1989

  • Softcover ISBN: 978-3-540-50961-5Published: 03 July 1989

  • eBook ISBN: 978-3-642-74615-4Published: 06 December 2012

  • Series ISSN: 1431-116X

  • Edition Number: 1

  • Number of Pages: XII, 310

  • Number of Illustrations: 14 b/w illustrations

  • Topics: Pharmacology/Toxicology, Cardiology, Neurology, Allergology, Immunology, Pharmacy

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