Overview
- Editors:
-
-
R. Rettig
-
German Institute for High Blood Pressure Research and Department of Pharmacology, University of Heidelberg, Heidelberg, West Germany
-
D. Ganten
-
German Institute for High Blood Pressure Research and Department of Pharmacology, University of Heidelberg, Heidelberg, West Germany
-
F. C. Luft
-
Indiana Univ. School of Medicine, Indianapolis, USA
Table of contents (32 papers)
-
-
Electrolyte and Volume Homeostasis
-
-
- D. Denton, M. McKinley, E. Tarjan, R. Weisinger
Pages 3-11
-
- E. Ritz, J. Mann, M. Schmid
Pages 12-22
-
- J. Ubl, H. Murer, H.-A. Kolb
Pages 23-32
-
Cellular Mechanisms
-
-
-
-
-
- D. Ely, B. Folkow, N. F. Paradise
Pages 66-82
-
- S. Oparil, Y.-F. Chen, R.-H. Yang, H. Jin, Q. C. Meng, E. J. Cragoe et al.
Pages 83-96
-
-
- P. J. Mulrow, E. Kusano, K. Baba, Y. Doi, D. Shier, R. Franco-Saenz
Pages 107-118
-
Genetic Determinants of Salt Sensitivity
-
Front Matter
Pages 119-119
-
- M. H. Weinberger, F. C. Luft, J. Z. Miller, C. E. Grim, N. S. Fineberg, J. C. Christian
Pages 121-127
-
- F. Skrabal, P. Kotanko, A. Lueger, B. Goedde, R. Balmes, M. Barenbrock et al.
Pages 128-138
-
- R. R. Williams, S. C. Hunt, S. J. Hasstedt, P. N. Hopkins, L. L. Wu, T. D. Berry et al.
Pages 139-155
-
Pathophysiological Significance of Different Types of Minerals
-
Front Matter
Pages 157-157
-
- T. B. Drüeke, C. Roullet, P. A. Lucas
Pages 159-168
-
- J. R. Sowers, P. Zemel, P. Standley, J. Kraniak, M. B. Zemel
Pages 169-175
About this book
Controversy regarding the wisdom of a high salt intake has been with us for 5000 years. In the Nei Ching, the oldest of the extant medical writings, the Yellow Emperor observed, "Hence, if too much salt is in the food, the pulse hardens, tears make their appearance, and the complexion changes". At about the same period in history, Job asked the question, "Can that which is unsavory be eaten without salt?" It is not apparent whether or not the Almighty provided a clear answer. The connection between dietary salt intake and hypertension was appreciated following the observations of AMBARD, BEAUJARD, VOLLHARD, ALLEN, and others. However, DAHL emphasized this relationship, as demonstrated by his epidemiological observations, his studies in human subjects, and his development of a genetically mediated form of salt-sensitive hypertension in rats. DAHL and his followers argued that hypertension was a disease of acculturation, or even of self-abuse. Undaunted by skeptics such as PICKERING, they suggested that if Western man would merely curtail his intake of the granular condiment, hypertension would not develop and blood pressure would not increase with age. Bucolic native societies were given as examples where such cardiovascular bliss was readily attained.
Editors and Affiliations
-
German Institute for High Blood Pressure Research and Department of Pharmacology, University of Heidelberg, Heidelberg, West Germany
R. Rettig,
D. Ganten
-
Indiana Univ. School of Medicine, Indianapolis, USA
F. C. Luft
