Developmental Neuropathology

1. Front Matter

   Pages I-XVI

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2. Introduction: Normal Development and Basic Reactions

   1. Front Matter

      Pages 1-1

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   2. Gross and Microscopic Development of the Central Nervous System

      • Reinhard L. Friede

      Pages 2-20

   3. Some Features of Basic Reactions Characteristic for Immature Nervous Tissue

      • Reinhard L. Friede

      Pages 21-25

3. Acquired Lesions in Newborns and Infants

   1. Front Matter

      Pages 27-27

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   2. Porencephaly, Hydranencephaly, Multicystic Encephalopathy

      • Reinhard L. Friede

      Pages 28-43

   3. Hemorrhages in Asphyxiated Premature Infants

      • Reinhard L. Friede

      Pages 44-58

   4. Lesions of Traumatic Birth and Other Causes of Hemorrhage

      • Reinhard L. Friede

      Pages 59-68

   5. Perinatal Lesions of White Matter

      • Reinhard L. Friede

      Pages 69-81

   6. Perinatal Lesions of Gray Matter

      • Reinhard L. Friede

      Pages 82-97

   7. Postnatal Lesions of Gray Matter

      • Reinhard L. Friede

      Pages 98-114

   8. Kernicterus (Bilirubin Encephalopathy)

      • Reinhard L. Friede

      Pages 115-124

   9. Arterial Diseases in Infancy

      • Reinhard L. Friede

      Pages 125-137

   10. Thrombosis of Intracranial Sinus and Veins

       • Reinhard L. Friede

       Pages 138-146

   11. Cerebral Lesions in Congenital Cardiac Disease

       • Reinhard L. Friede

       Pages 147-151

   12. Craniocerebral Trauma in Infancy

       • Reinhard L. Friede

       Pages 152-155

   13. Infections of the Fetus

       • Reinhard L. Friede

       Pages 156-168

   14. Purulent Leptomeningitis in Newborns and Infants

       • Reinhard L. Friede

       Pages 169-179

   15. Meningoencephalitic Processes in the Peri- and Postnatal Periods, Including CNS Involvement by some Hematologic Diseases

       • Reinhard L. Friede

       Pages 180-197

   16. Subdural Hematomas, Hygromas and Effusions

       • Reinhard L. Friede

       Pages 198-208

I was gratified by the most favorable reception and wide usage received by the first edition of this book. A decade seems to be a short period for a book on pathology, and yet it witnessed many important changes of concepts, along with a formidable growth of knowledge. The second edition required extensive reorganization. There are new chapters on mitochondriopathies, on peroxisomal diseases and on spongy myelino­ pathies. Major revisions and new additions were necessary in many chapters, for instance those on the dysplasias of the cerebral and of the cerebellar hemispheres, which were largely reorganized. The chapters on perinatal pathology were reordered and reorganized to give a more logical sequence of prenatal, perinatal and postnatal lesions. The entire text was worked over for brevity. A wealth of new references was added with the. aim of staying abreast with the literature up to summer 1988. All refer­ ences were double checked for errors. My gratitude goes to Mrs. Gisela Ropte and Mrs. Cynthia Bunker for their untiring, diligent help. As a result, this second edition is an essentially rewritten text. Advance in the prevention of human suffering is based on a thorough understand­ ing of the nature of disease. I hope that this text will continue to be of service in this behalf. Perhaps it may also reflect and foster the intellectual curiosity which makes the "reading of brains" so interesting an occupation. Gottingen, 1989 Reinhard L.

• Hydrocephalus
• aneurysm
• brain
• cell
• epilepsy
• intracranial pressure
• muscle
• myelin
• nervous system
• neurons
• neuropathology
• pathology
• spinal cord
• tissue
• trauma

• Zentrum Neurologische Medizin, Abteilung Neuropathologie, Georg-August-Universität Göttingen, Göttingen, Germany

  Reinhard L. Friede

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