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  • Conference proceedings
  • © 1988

Surfactant Replacement Therapy

in Neonatal and Adult Respiratory Distress Syndrome

Editors:

  1. Burkhard Lachmann

    1. Department of Anesthesiology, Erasmus University, Rotterdam, The Netherlands

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Table of contents (45 papers)

  1. Front Matter

    Pages I-XXII
    PDF

  2. Pulmonary Surfactant: Evolution of Functional Concepts

  3. Experimental Evaluation of Surfactant for Replacement Therapy

    1. Front Matter

      Pages 11-11
      PDF

    2. Evaluation of Pulmonary Surfactant

      • G. Enhorning
      Pages 13-17

    3. Some Remarks on the Use of Physico-Chemical Methods in Lung Surfactant Research

      • P. Gieles, T. Key, J. Van Santvoort, A. Steeghs
      Pages 18-27

    5. Efficacy and Standardisation of SF-RI 1: A Preparation from Bovine Lung Surfactant

      • B. Disse, L. Gortner, E. Weller, H. Eberhardt, H. Ziegler
      Pages 37-41

    6. Comparison Between Natural and Artificial Surfactant Preparations in Premature Rabbit Fetuses

      • B. Disse, E. Weller, L. Lützen, H. Ziegler, H. Eberhardt
      Pages 42-46

  4. Diagnostics of Surfactant Deficiency

    1. Front Matter

      Pages 47-47
      PDF

    3. Diagnosis of Surfactant Defects in Newborn, Children and Adults in the Era of Surfactant Therapy

      • M. Hallman, J. L. Abraham, O. Pitkänen, P. Arjomaa
      Pages 58-65

  5. Surfactant Replacement in Newborn Infants

    1. Front Matter

      Pages 89-89
      PDF

    7. Ventilator Settings After Surfactant Replacement with SF-RI 1: Clinical Experiences

      • L. Gortner, F. Pohlandt, P. Bartmann, B. Disse, E. Weller
      Pages 134-135
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About this book

I am very happy and honoured to have so many famous contrib­ utors from around the world presenting their knowledge and experience in this book, including Dr. Rufer who, as early as 1967, attempted to improve the pressure-volume curve of a child dying from RDS using dried surfactant from dogs; Drs. Enhorn­ ing and Robertson who were the first to treat rabbit fetuses with surfactant replacement and impressively demonstrated that sur­ factant improved lung mechanics; and Dr. Fujiwara who at the end of the 1970's had already successfully treated the first babies with surfactant replacement and published this work al­ ready in 1980. Thus, the idea of surfactant replacement therapy is now more or less 20 years old and almost 10 years have passed since the first publication by Dr. Fujiwara of his impressive clinical results. Up to now (September, 1988) about 2,200 babies have been treated worldwide with tracheal instillation of surfactant, with most promising results. The type of surfactant used varies from pure natural extracts from bovine or pig lungs, to surfactant extracted from human amniotic fluid, to pure phospholipids. To date, however, there is still no surfactant commercially available (except in Japan), in spite of the fact that it is urgently awaited by neonatologists and intensive care doctors throughout the world. This volume is based on the contributions presented at the international congress on Surfactant Replacement Therapy which was held in Rotterdam, The Netherlands, in November 1987.
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Keywords

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Editors and Affiliations

  • Department of Anesthesiology, Erasmus University, Rotterdam, The Netherlands

    Burkhard Lachmann

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Bibliographic Information

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Buy it now

eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

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