The Cholinergic Synapse

1. Front Matter

   Pages I-XXV

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2. Model Cholinergic Systems

   1. Front Matter

      Pages 1-1

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   2. Model Cholinergic Systems: An Overview

      • V. P. Whittaker

      Pages 3-22

   3. Model Cholinergic Systems: The Electromotor System of Torpedo

      • V. P. Whittaker, D. W. Schmid

      Pages 23-39

   4. Model Cholinergic Systems: The Avian Ciliary Ganglion

      • G. R. Pilar, D. A. Johnson

      Pages 41-54

3. Biology of the Cholinergic Synapse

   1. Front Matter

      Pages 55-55

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   2. Phylogeny of the Cholinergic Synapse

      • K. Wächtler

      Pages 57-80

   3. Development of the Cholinergic Synapse: Role of Trophic Factors

      • G. P. Richardson

      Pages 81-100

4. Molecular Components of the Cholinergic System

   1. Front Matter

      Pages 101-101

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   2. Estimation of Acetylcholine and Choline and Analysis of Acetylcholine Turnover Rates In Vivo

      • P. E. Potter, I. Hanin

      Pages 103-124

   3. Choline Acetyltransferase and the Synthesis of Acetylcholine

      • S. Tuček

      Pages 125-165

   4. Vertebrate Cholinesterases: Structure and Types of Interaction

      • J. Massoulié, J.-P. Toutant

      Pages 167-224

   5. Cholinesterases: Tissue and Cellular Distribution of Molecular Forms and Their Physiological Regulation

      • J.-P. Toutant, J. Massoulié

      Pages 225-265

   6. Structure and Function of the Nicotinic Acetylcholine Receptor

      • A. Maelicke

      Pages 267-313

   7. Muscarinic Acetylcholine Receptors

      • J. Järv, T. Bartfai

      Pages 315-345

5. Cellular Organization of the Cholinergic System

   1. Front Matter

      Pages 347-347

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   2. Cholinergic Synaptic Vesicles

      • H. Zimmermann

      Pages 349-382

   3. Isolation of Cholinergic Nerve Terminals

      • P. J. Richardson

      Pages 383-397

   4. Axonal Transport in Cholinergic Neurons

      • M. Tytell, H. Stadler

      Pages 399-407

   5. The High-Affinity Choline Uptake System

      • I. Ducis

      Pages 409-445

One of the most impressive works of scholarship in the field of experimental pharmacology has been the Heffter-Heubner Handbuch der experimentellen Pharmakologie, internationalized some years ago under the title Handbook 0/ Experimental Pharmacology and kept up to date by a series of numbered Ergiin­ zungswerke or supplementary volumes which have now replaced in importance the original Handbuch. These volumes constitute a valuable and continuously up­ dated multi author review series of topics important in modern pharmacology and allied sciences. The Editorial Board of the Handbook invited me 2 years ago to undertake, as subeditor, the preparation of a new volume entitled The Cholinergic Synapse. A previous volume in this series, vol. 15, Cholinesterases and Anticholinesterase Agents, edited by GEORGE KOELLE, was published in 1963 and was far wider in scope than its title suggested: it was, in fact an authoritative summing up of the whole subject of cholinergic function and still has some value today as an account of the state of the art as it was at that time. Since then another excellent review, of a specific cholinergic synapse, has appeared in this series: this was vol. 42, Neuromuscular Junction, edited by ELEANOR ZAIMIS and published in 1976. A third volume, vol. 53, Pharmacology o/Ganglionic Transmission, which appeared in 1980 and was edited by D. A. KHARKEVICH, includes important aspects of autonomic cholinergic function.

• Antigen
• Nervous System
• biology
• neurobiology
• neurons
• neuropathology

• Arbeitsgruppe Neurochemie, Max-Planck-Institut für biophysikalische Chemie, Göttingen, Germany

  Victor P. Whittaker

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