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Antigen Presentation

  • Book
  • © 1998

Overview

Editors:
  1. J. Lindsay Whitton

    1. Department of Neuropharmacology, CVN-9, The Scripps Research Institute, La Jolla, USA

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Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 232)

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Table of contents (10 chapters)

  1. Front Matter

    Pages I-IX
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  2. An Overview of Antigen Presentation and Its Central Role in the Immune Response

    • J. Lindsay Whitton
    Pages 1-13

  3. How Do Endogenous Proteins Become Peptides and Reach the Endoplasmic Reticulum

    • Dipankar Nandi, Kate Marusina, John J. Monaco
    Pages 15-47

  4. Molecular Requirements for Assembly and Intracellular Transport of Class I Major Histocompatibility Complex Molecules

    • Anne M. Fourie, Young Yang
    Pages 49-74

  5. Peptide-Major Histocompatibility Complex Class I Complex: From the Structural and Molecular Basis to Pharmacological Principles and Therapeutic Applications

    • Denis Hudrisier, Jean Edouard Gairin
    Pages 75-97

  6. Immune Response of β2-Microglobulin-Deficient Mice to Pathogens

    • Jeffrey A. Frelinger, Jonathan Serody
    Pages 99-114

  7. CNS Neurons: The Basis and Benefits of Low Class I Major Histocompatibility Complex Expression

    • Glenn F. Rall
    Pages 115-134

  8. Suppression of MHC Class I Antigen Presentation by Human Adenoviruses

    • Tim E. Sparer, Linda R. Gooding
    Pages 135-147

  9. Herpesvirus Evasion of the Immune System

    • David C. Johnson, Ann B. Hill
    Pages 149-177

  10. Intracellular Transport of Molecules Engaged in the Presentation of Exogenous Antigens

    • Tommy W. Nordeng, Jean-Pierre Gorvel, Oddmund Bakke
    Pages 179-215

  11. Biologic Consequences of Defective Major Histocompatibility Complex Class II Presentation

    • Martha M. Eibl, Hermann M. Wolf
    Pages 217-240

  12. Back Matter

    Pages 241-246
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Keywords

About this book

Antigen presentation is central to the immune response, and is instrumental in ensuring that the response mounted is that best suited to the eradication of the particular microbe faced. In this volume, experts in the field provide state-of-the-art descriptions of the antigen presentation pathways. How do viruses disrupt these critical pathways, and to what effect? Do all tissues present antigen in the same way? If not, why? What are the consequences of dysfunctional antigen presentation, seen in certain genetic disorders? This book considers not only the molecular details, but also their relevance to the whole organism.

Editors and Affiliations

  • Department of Neuropharmacology, CVN-9, The Scripps Research Institute, La Jolla, USA

    J. Lindsay Whitton

Bibliographic Information

  • Book Title: Antigen Presentation

  • Editors: J. Lindsay Whitton

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-72045-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 1998

  • Softcover ISBN: 978-3-642-72047-5Published: 19 January 2012

  • eBook ISBN: 978-3-642-72045-1Published: 07 March 2013

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: X, 244

  • Number of Illustrations: 3 illustrations in colour

  • Topics: Immunology, Microbiology, Molecular Medicine

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