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Protein Secretion and Export in Bacteria

  • Conference proceedings
  • © 1986

Overview

Editors:
  1. Henry C. Wu

    1. Uniformed Services University of the Health Sciences, Bethesda, USA

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  2. Phang C. Tai

    1. Department of Metabolic Regulation, Boston Biomedical Research Institute, Boston, USA
      Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 125)

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Table of contents (11 papers)

  1. Front Matter

    Pages I-X
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  2. Past Triumphs, Future Challenges

    • B. D. Davis
    Pages 1-3

  3. Genetic Studies on Protein Export in Bacteria

    • J. Beckwith, S. Ferro-Novick
    Pages 5-27

  4. The Membrane Trigger Hypothesis Revisited

    • B. Wickner
    Pages 29-31

  5. In Vitro Analysis of the Bacterial Protein Export

    • M. Müller, G. Blobel
    Pages 33-41

  6. Biochemical Studies of Bacterial Protein Export

    • P. C. Tai
    Pages 43-58

  7. Secretion Cloning Vectors for Guiding the Localization of Proteins in Vivo

    • C. A. Lunn, M. Takahara, M. Inouye
    Pages 59-74

  8. Signal Peptidases

    • P. Ray, I. Dev, C. MacGregor, P. Bassford Jr.
    Pages 75-102

  9. Protein Secretion in Bacilli

    • M. Sarvas
    Pages 103-125

  10. Biogenesis of Lipoproteins in Bacteria

    • H. C. Wu, M. Tokunaga
    Pages 127-157

  11. Secretion of Haemolysin by Escherichia coli

    • N. Mackman, J.-M. Nicaud, L. Gray, I. B. Holland
    Pages 159-181

  12. Production and Release of Cloacin DF13 and Related Colicins

    • F. K. De Graaf, B. Oudega
    Pages 183-205

  13. Back Matter

    Pages 207-211
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Keywords

About this book

The last decade has witnessed rapid progress in our under­ standing of the mechanisms of protein export and secretion in both prokaryotic and eukaryotic cells. Studies of protein secretion across the membranes of the rough endoplasmic reticulum have led to the formulation of the now-classic signal hypothesis, which has stimulated many discussions and new ideas, and the identification of the signal recogni­ tion particle as an organelle in the initiation of the export process. However, more recent work pertaining to intrage­ nic information related to targeting specific proteins for either secretion or membrane localization, the energetics of protein secretion, the timing of synthesis versus the initia­ tion of export, structural requirements for the processing of precursor proteins, and the identification of the proces­ sing enzymes (signal peptidases), has been the result of a combined biochemical and genetic approach to the study of protein localization in bacteria. While reviews on the biochemistry and genetics of pro­ tein secretion have appeared frequently in recent years, this book attempts to summarize the current status and the future perspectives of this rapidly moving field in a single volume. Topics covered in this book include the genetics of protein secretion in E. coli, biochemical analysis of pro­ tein export in vitro, signal peptidases, excretion of colicins and hemolysin in E. coli, protein secretion in Bacillus, and protein secretion cloning vectors.

Editors and Affiliations

  • Uniformed Services University of the Health Sciences, Bethesda, USA

    Henry C. Wu

  • Department of Metabolic Regulation, Boston Biomedical Research Institute, Boston, USA

    Phang C. Tai

  • Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, USA

    Phang C. Tai

Bibliographic Information

  • Book Title: Protein Secretion and Export in Bacteria

  • Editors: Henry C. Wu, Phang C. Tai

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-71251-7

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 1986

  • Softcover ISBN: 978-3-642-71253-1Published: 17 November 2011

  • eBook ISBN: 978-3-642-71251-7Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: X, 211

  • Topics: Medical Microbiology, Allergology, Immunology

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