Thermodynamic Data for Biochemistry and Biotechnology

1. Front Matter

   Pages I-XVI

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2. Introduction

   1. Front Matter

      Pages 1-1

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   2. Present and Future Uses and a Bit of History

      • John T. Edsall

      Pages 3-13

3. Nonreacting Systems

   1. Front Matter

      Pages 15-15

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   2. Partial Molar Volumes of Biochemical Model Compounds in Aqueous Solution

      • Harald Høiland

      Pages 17-44

   3. Specific Volumes of Biological Macromolecules and Some Other Molecules of Biological Interest

      • Helmut Durchschlag

      Pages 45-128

   4. Partial Molar Compressibilities of Organic Solutes in Water

      • Harald Høiland

      Pages 129-147

   5. Heat Capacities of Biological Macromolecules

      • George M. Mrevlishvili

      Pages 148-176

   6. Thermodynamics of Carbohydrate Monomers and Polymers in Aqueous Solution

      • Attilio Cesàro

      Pages 177-207

4. Interactions in Solution

   1. Front Matter

      Pages 209-209

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   2. Thermodynamic Data for Protein-Ligand Interaction

      • Heiner Wiesinger, Hans Jürgen Hinz

      Pages 211-226

   3. Thermodynamics of Protein-Protein Association

      • Philip D. Ross

      Pages 227-233

   4. Hemoglobin

      • B. George Barisas

      Pages 234-255

5. Solution Processes

   1. Front Matter

      Pages 257-257

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   2. Gas-Liquid and Solid-Liquid Phase Equilibria in Binary Aqueous Systems of Nonelectrolytes

      • Sergio Cabani, Paolo Gianni

      Pages 259-275

   3. Thermodynamic Parameters of Biopolymer-Water Systems

      • Madeleine Lüscher-Mattli

      Pages 276-294

6. Phase Changes

   1. Front Matter

      Pages 295-295

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   2. The Formation of Micelles

      • Heinz Hoffmann, Werner Ulbricht

      Pages 297-348

   3. Unfolding of Proteins

      • Wolfgang Pfeil

      Pages 349-376

   4. The Thermodynamics of Conformation Transitions in Polynucleotides

      • Vladimir V. Filimonov

      Pages 377-401

The strong trend in the Biological Sciences towards a quantitative characterization of processes has promoted an increased use of thermo­ dynamic reasoning. This development arises not only from the well­ known power of thermodynamics to predict the direction of chemical change, but also from the realization that knowledge of quantitative thermodynamic parameters provides a deeper understanding of many biochemical problems. The present treatise is concerned primarily with building up a reliable data base, particularly ofbiothermodynamic and related quantities, such as partial specific volumes and compressibilities, which will help scientists in basic and applied research to choose correct data in a special field that may not be their own. Most chapters reflect this emphasis on data provision. However, it was also felt that the expert user deserved information on the basic methodology of data acquisition and on the criteria of data selection. Therefore all tables are preceded by a critical evaluation of the techniques as well as a survey of the pertinent studies in the corresponding areas. The surveys are usually self-consistent and provide references to further sources of data that are important but not covered in the present volume. The reader will realize that in different chapters, different symbols have be~n used for the same properties. This unfortunate situation is particularly obvious in those chapters where partial specific or molar quantities had to be introduced; however, it also occurs in those contributions concerning phase changes of macromolecules.

• Fortuna
• base
• biochemistry
• biotechnology
• chemistry
• thermodynamics

• Institut für Biophysik und Physikalische Biochemie, Universität Regensburg, Regensburg, Germany

  Hans-Jürgen Hinz

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