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Immunology of the Neonate

  • Conference proceedings
  • © 1987

Overview

Editors:
  1. G. Roberto Burgio

    1. Clinica Pediatrics, Universitá di Pavia, Pavia, Italy

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  2. Lars Åke Hanson

    1. Institute of Clinical Microbiology, University of Götebôrg, Göteborg, Sweden

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  3. Alberto G. Ugazio

    1. Clinica Pediatrica Ospedale dei Bambini, University of Brescia, Brescia, Italy

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Table of contents (19 papers)

  1. Front Matter

    Pages I-IX
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  2. Immunologic Development Introductory Remarks

    • Robert A. Good
    Pages 1-4

  3. T-Cell Development

    • O. Stutman
    Pages 5-26

  4. Humoral Immunity in the Human Neonate

    • Joseph L. Butler, Takayo Suzuki, Hiromi Kubagawa, Max D. Cooper
    Pages 27-36

  5. Regulation of Antibody Synthesis in the Neonate

    • Ulf Andersson
    Pages 37-50

  6. The Ontogeny of the Immune Response: The Role of Maternal Factors

    • L. Å. Hanson, I. Adlerberth, B. Carlsson, U. Dahlgren, Fehmida Jalil, Shaukat R. Khan et al.
    Pages 51-58

  7. Mononuclear Phagocyte Function in the Perinatal Period

    • A. Biondi, G. Poli, C. Parravicini, A. Molinari, A. Mantovani
    Pages 59-66

  8. Mechanisms of Abnormal Neutrophil Function in the Human Neonate: Prospects for Therapy

    • Harry R. Hill, Fulvio Sacchi
    Pages 67-75

  9. Complement Function in the Neonate

    • F. Sessions Cole
    Pages 76-82

  10. Modulation of Nonspecific Defense Mechanisms in the Neonate

    • Francesco Laurenti
    Pages 83-93

  11. T-Cell Development and Function: Relationship to Immunodeficiencies

    • F. Aiuti, R. Paganelli, B. Ensoli, M. Crescenzi, M. Carbonari, M. Fiorilli
    Pages 94-99

  12. Activation and Functional Capacity of Neonatal T Cells: Analysis of Interleukin-2 and Interleukin-2 Receptor Responsiveness

    • David L. Nelson
    Pages 100-111

  13. Development of Lymphocyte Responses to Herpes Simplex Virus Following Neonatal Infection

    • Anthony Hayward, Paul Leibson, Ann Arvin
    Pages 112-119

  14. T and NK Lymphocyte Subpopulations in the Neonate

    • Rita Maccario, G. R. Burgio
    Pages 120-129

  15. Analysis of the Immunological Dysregulation Underlying Defective Interferon γ Secretion in the Human Neonate

    • J. L. Virelizier, N. Wakasugi
    Pages 130-134

  16. Immunity and Infections in the Neonate

    • Joseph A. Bellanti, Barbara J. Zeligs
    Pages 135-144

  17. Intravenous Gammaglobulin Replacement for Prophylaxis of Infection in Preterm Neonates

    • Gaetano Chirico, Giorgio Rondini, Alessandro Plebani, Alberto Chiara, Alberto G. Ugazio
    Pages 145-152

  18. Prevention of Atopy: Neonatal Aspects

    • Robert N. Hamburger, Seth M. Asser
    Pages 153-160

  19. Treatment of Infants with Severe Combined Immunodeficiency by Bone Marrow or Fetal Liver Transplantation

    • Jean-Louis Touraine
    Pages 161-169

  20. Summing Up

    • Robert A. Good
    Pages 170-185
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Keywords

About this book

Over the last few years, many new observations have profoundly changed our concepts of the immune competence of the newborn. For the immune system, as for other systems and functions, the neonatal age represents a crucial transition period. In fact the immune characteristics of the fetus are likely to result fro- or be conditioned by - several often contradictory physiological requirements. On the one hand, it would certainly be an advantage for the fetus to acquire a complete immunocompetence as soon as possible in order to be able to cope with the eventual transplacental passage of pathogenic microorganisms and possibly also in order to reject maternal cells occasionally crossing the placental nd barrier. This is actually what occurs, at least in part, during the 2 and Jfd month of gestation when the fetus begins to acquire his biological individuality and at the same time the role of a "biological ego" resulting from the attain­ ment by the immune system of the capacity to discriminate between self and nonself.

Editors and Affiliations

  • Clinica Pediatrics, Universitá di Pavia, Pavia, Italy

    G. Roberto Burgio

  • Institute of Clinical Microbiology, University of Götebôrg, Göteborg, Sweden

    Lars Åke Hanson

  • Clinica Pediatrica Ospedale dei Bambini, University of Brescia, Brescia, Italy

    Alberto G. Ugazio

Bibliographic Information

  • Book Title: Immunology of the Neonate

  • Editors: G. Roberto Burgio, Lars Åke Hanson, Alberto G. Ugazio

  • DOI: https://doi.org/10.1007/978-3-642-71094-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1987

  • Softcover ISBN: 978-3-642-71096-4Published: 17 November 2011

  • eBook ISBN: 978-3-642-71094-0Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: X, 188

  • Topics: Immunology, Pediatrics, Allergology

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