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Epidemiological Concepts in Clinical Pharmacology

  • Conference proceedings
  • © 1987

Overview

Editors:
  1. Helmut Kewitz

    1. Institute of Clinical Pharmacology, Klinikum Steglitz of the Free University of Berlin, Berlin 45, Federal Republic of Germany

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  2. Ivar Roots

    1. Institute of Clinical Pharmacology, Klinikum Steglitz of the Free University of Berlin, Berlin 45, Federal Republic of Germany

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  3. Karlheinz Voigt

    1. Institute of Clinical Pharmacology, Klinikum Steglitz of the Free University of Berlin, Berlin 45, Federal Republic of Germany

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Table of contents (17 papers)

  1. Front Matter

    Pages I-XII
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  2. Opening Remarks

    • H. Kewitz
    Pages 1-1

  3. The Thalidomide Hypothesis: How It Was Found and Tested

    • W. Lenz
    Pages 3-10

  4. Reasons for the Successes and Failures of Specific Models in Drug Epidemiology

    • Samuel Shapiro
    Pages 11-22

  5. Methodological Concepts: What Could We Know and What Should We Know in Drug Epidemiology?

    • K. Überla
    Pages 23-33

  6. The Design of Case-Control Studies

    • H. J. Jesdinsky
    Pages 34-42

  7. Methodological Evaluation of Studies in Drug Epidemiology

    • Olli P. Heinonen
    Pages 43-49

  8. Problems with International Evaluation of Drug Risks

    • Åke Liljestrand
    Pages 50-56

  9. Drug Utilization Studies — an Instrument in Drug Research

    • P. K. M. Lunde, M. Andrew, I. Baksaas
    Pages 57-72

  10. Observational Cohort Study in General Practice: Differences and Equivalences Among Analgesics for Treatment of Colic Pain

    • H. Kewitz, G. Härter, U. Feldmann, G. Kreutz, M. Nitz, E. Unger
    Pages 73-86

  11. Oxprenolol in Myocardial Infarction Survivors: Brief Review of the European Infarction Study Results in the Light of Other Beta-Blocker Post Infarction Trials

    • R. Schröder
    Pages 87-99

  12. The Epidemiological Evaluation of Major Upper Gastrointestinal Bleeding in Relation to Aspirin Use

    • Micha Levy
    Pages 100-104

  13. The Role of Pharmacogenetics in Drug Epidemiology

    • I. Roots, G. Heinemeyer, N. Drakoulis, D. Kampf
    Pages 105-118

  14. Possibilities and Limitations of a Modified Spontaneous ADR Monitoring System Available to Practitioners in Germany

    • Ellen Weber
    Pages 119-124

  15. Prescription of Psychotropic Drugs in Germany

    • B. Müller-Oerlinghausen, L. G. Schmidt
    Pages 125-137

  16. The Benefit-Risk Evaluation of Drugs by Health Authorities in the Federal Republic of Germany

    • Gottfried Kreutz
    Pages 138-142

  17. Postmarketing Surveillance of Drugs: Visions of the Future

    • Olli S. Miettinen
    Pages 143-147

  18. Closing Remarks

    • H. Kewitz
    Pages 148-148
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Keywords

About this book

Clinical pharmacology is not primarily characterized by a particular methodology, but rather by the aims it pursues. Cooperation with scientists in other fields is thus essential. The symposium "Epidemiological Concepts in Clinical Pharmacology" (November 28-29, 1985) was organized by the Institute of Clinical Pharmacology of the Free University of Berlin to acknowledge the increasing impact of epidemio­ logical methods and thinking on clinical pharmacology. The editors are glad that all the presentations of the leading experts can now be made available to a broader rea­ dership. Neither the symposium itself nor publication of the proceedings would have been possible without the generous support received from the Paul-Martini-Stif­ tung and from the Free University of Berlin. To these institutions we owe deep grati­ tude. The expert guidance we received from Dr. Ute Heilmann of Springer-Verlag is also gladly acknowledged. Berlin, November 1986 H.Kewitz I. Roots K. Voigt Contents Opening Remarks 1 H.Kewitz ..... The Thalidomide Hypothesis: How It Was Found and Tested W.Lenz ............................. . 3 Reasons for the Successes and Failures of Specific Models in Drug Epidemiology S. Shapiro ... . . . . . . . . . . . . . . . . . . . . . . . . . .. . . 11 . . . Methodological Concepts: What Could We Know and What Should We Know in Drug Epidemiology K. Obeda. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 23 . . . . . . The Design of Case-Control Studies H.J.Jesdinsky ............ . . ........ 34 Methodological Evaluation of Studies in Drug Epidemiology O. P. Heinonen. . . . . . . . . . . . . . . . . . . . . . . .. . . 43 . . . . . Problems with International Evaluation of Drug Risks A. Liljestrand ....................... . . . . . . .. . . 50 Drug Utilization Studies -an Instrument in Drug Research P. K. M. Lunde, M. Andrew, I. Baksaas . . . . . . . . . . . . . . .. . . 57 . .

Editors and Affiliations

  • Institute of Clinical Pharmacology, Klinikum Steglitz of the Free University of Berlin, Berlin 45, Federal Republic of Germany

    Helmut Kewitz, Ivar Roots, Karlheinz Voigt

Bibliographic Information

  • Book Title: Epidemiological Concepts in Clinical Pharmacology

  • Editors: Helmut Kewitz, Ivar Roots, Karlheinz Voigt

  • DOI: https://doi.org/10.1007/978-3-642-71043-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin, Heidelberg 1987

  • Softcover ISBN: 978-3-642-71045-2Due: 17 November 2011

  • eBook ISBN: 978-3-642-71043-8Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XII, 148

  • Topics: Pharmacology/Toxicology, Pharmacy

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