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The Contribution of Acute Toxicity Testing to the Evaluation of Pharmaceuticals

  • Conference proceedings
  • © 1986

Overview

Editors:
  1. Dietrich Schuppan

    1. Medical and Scientific Affairs, Bundesverband der Pharmazeutischen Industrie e.V., Frankfurt am Main 1, Germany

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  2. Anthony D. Dayan

    1. DHSS Dept. of Toxicology, St. Bartholomew’s Hospital Medical College, GB-London, UK

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  3. Frances A. Charlesworth

    1. The Association of the British Pharmaceutical Industry — ABPI, GB-London, UK

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Table of contents (19 papers)

  1. Front Matter

    Pages I-XII
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  2. Opening remarks

    1. Opening remarks

      • G. Fülgraff
      Pages 1-2

  4. Current Regulatory View on Acute Toxicity Testing

    1. Front Matter

      Pages 53-53
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    2. EEC/CPMP

      • R. Bass
      Pages 55-59

    3. Appendix

      • Dietrich Schuppan, Anthony D. Dayan, Frances A. Charlesworth
      Pages 60-60

    4. Single Dose Toxicity

      • Dietrich Schuppan, Anthony D. Dayan, Frances A. Charlesworth
      Pages 61-64

    5. A US/FDA View of Acute Toxicity Testing in the Evaluation of Pharmaceuticals

      • L. M. Crawford
      Pages 65-73

    6. Current Regulatory View of Acute Toxicity Testing in Japan

      • M. Tezuka, A. Takanaka
      Pages 74-80

    7. Alternatives to Animals in Toxicological Assessment and Notifications

      • V. H. Morgenroth
      Pages 81-85

  5. Summary Reports of Group Discussions

    1. Front Matter

      Pages 87-87
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    2. Introductory Comments on Ethical Aspects of Acute Toxicity Testing

      • A. D. Dayan
      Pages 89-90

    3. Scientific Constraints on the Use of Acute Toxicity Testing

      • A. D. Dayan, B. B. Newbould
      Pages 91-92

    4. Practical Constraints on the Use of Acute Toxicity Testing

      • F. Clementi, J. M. Frazier
      Pages 93-94
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Keywords

Editors and Affiliations

  • Medical and Scientific Affairs, Bundesverband der Pharmazeutischen Industrie e.V., Frankfurt am Main 1, Germany

    Dietrich Schuppan

  • DHSS Dept. of Toxicology, St. Bartholomew’s Hospital Medical College, GB-London, UK

    Anthony D. Dayan

  • The Association of the British Pharmaceutical Industry — ABPI, GB-London, UK

    Frances A. Charlesworth

Bibliographic Information

  • Book Title: The Contribution of Acute Toxicity Testing to the Evaluation of Pharmaceuticals

  • Editors: Dietrich Schuppan, Anthony D. Dayan, Frances A. Charlesworth

  • DOI: https://doi.org/10.1007/978-3-642-70390-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1986

  • Softcover ISBN: 978-3-642-70392-8Published: 19 November 2011

  • eBook ISBN: 978-3-642-70390-4Published: 14 November 2014

  • Edition Number: 1

  • Number of Pages: XII, 104

  • Topics: Pharmacology/Toxicology, Pharmacy

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