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Clinical Pharmacology of Antianginal Drugs

  • Book
  • © 1985

Overview

Editors:
  1. Ulrich Abshagen

    1. Boehringer Mannheim GmbH, Mannheim 31, Germany

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Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 76)

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Table of contents (13 chapters)

  1. Front Matter

    Pages I-XVI
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  2. General Principles

    1. Front Matter

      Pages 1-1
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    2. Epidemiology of Ischemic Heart Disease

      • S. Heyden
      Pages 3-45

    3. Pathophysiology of Coronary Circulation and of Acute Coronary Insufficiency

      • W. Schaper, J. Schaper, H. M. Hoffmeister
      Pages 47-96

    4. Pharmacodynamic Principles of Action of Antianginal Drugs

      • O. Kraupp
      Pages 97-115

  3. Test Methods

    1. Front Matter

      Pages 117-117
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    2. Experimental Testing of Antianginal Drugs in Animals

      • G. Raberger
      Pages 119-151

    3. Noninvasive Methods: Systolic Time Intervals and Echocardiography

      • P. J. Oldershaw, D. G. Gibson
      Pages 153-172

    4. Peripheral Circulation

      • I. C. Roddie, W. F. M. Wallace
      Pages 173-196

    5. Exercise Testing

      • D. Redwood
      Pages 197-212

    6. Radionuclide Methods

      • W. E. Adam, M. Stauch
      Pages 213-237

    7. Assessment of Coronary Artery Disease and Myocardial Ischemia by Invasive Methods

      • C. Nienaber, W. Bleifeld
      Pages 239-284

  4. Types of Antianginal Drugs

    1. Front Matter

      Pages 285-285
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    2. Organic Nitrates

      • U. Abshagen
      Pages 287-364

    3. Molsidomine

      • J. Scholtholt
      Pages 365-383

    4. β-Adrenoceptor Blocking Agents

      • B. N. C. Prichard
      Pages 385-458

    5. Calcium Antagonists

      • P. G. Hugenholtz
      Pages 459-538

  5. Back Matter

    Pages 539-552
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Keywords

About this book

When I was asked some years ago by the editors of the Handbook of Experimental Pharmacology to edit a new volume on Antianginal Drugs, I agreed on the condition that, in accordance with my scientific background, primary emphasis be given to clinical pharmacology and therapeutics. It soon turned out that, due to rapid developments in this field, nothing of the previous volume on Antianginal Drugs by Charlier (Vol. 31, 1971) could be retained apart from its basic idea of devoting considerable space to methodology. Since editors must operate within certain limits, I had to abstain from dealing with acute myocardial infarction in detail despite the well-known overlap between unstable angina, the preinfarction syndrome, and acute myocardial infarction. It was only possible for acute myocardial infarction and the concept of reduction of infarct size to be briefly discussed within the chapter on pathophysiology of acute coronary insufficiency. The chapter on invasive methods provided an opportunity to touch on new approaches to early intervention in acute myocardial infarction. Here, intracoronary streptokinase therapy and PTCA are considered, again with attention to the overlap between mechanical and pharmacological interventions.

Editors and Affiliations

  • Boehringer Mannheim GmbH, Mannheim 31, Germany

    Ulrich Abshagen

Bibliographic Information

  • Book Title: Clinical Pharmacology of Antianginal Drugs

  • Editors: Ulrich Abshagen

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-642-69524-7

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1985

  • Softcover ISBN: 978-3-642-69526-1Published: 07 December 2011

  • eBook ISBN: 978-3-642-69524-7Published: 06 December 2012

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: XVI, 552

  • Topics: Pharmacology/Toxicology, Cardiology, Pharmacy

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