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Radiocontrast Agents

  • Book
  • © 1984

Overview

Editors:
  1. Milos Sovak

    1. School of Medicine, Department of Radiology, S-009, University of California in San Diego, La Jolla, USA
      Biophysica Foundation, La Jolla, USA

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Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 73)

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Table of contents (15 chapters)

  1. Front Matter

    Pages I-XVI
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  2. Introduction: State of the Art and Design Principles of Contrast Media

    • M. Sovak
    Pages 1-22

  3. Chemistry of X-Ray Contrast Media

    • G. B. Hoey, K. R. Smith
    Pages 23-125

  4. Urographic Contrast Media and Methods of Investigative Uroradiology

    • K. Golman, T. Almén
    Pages 127-191

  5. Contrast Media in the Cardiovascular System

    • C. B. Higgins
    Pages 193-251

  6. Basic Methods of Investigative Cardiovascular Radiology

    • M. Sovak, C. B. Higgins
    Pages 253-294

  7. Contrast Media for Imaging of the Central Nervous System

    • M. Sovak
    Pages 295-340

  8. Basic Methods of Investigative Neuroradiology

    • M. Sovak
    Pages 341-366

  9. Hepatic Disposition and Elimination of Biliary Contrast Media

    • J. L. Barnhart
    Pages 367-418

  10. Laboratory Techniques for Studying Biliary Contrast Media

    • J. L. Barnhart
    Pages 419-461

  11. Contrast Media in Lymphography

    • M. Sovak
    Pages 463-477

  12. Contrast Media in Computed Tomography

    • P. B. Dean, D. B. Plewes
    Pages 479-523

  13. Adverse Systemic Reactions to Contrast Media

    • E. C. Lasser
    Pages 525-532

  14. Are Contrast Media Mutagenic?

    • J. A. Nelson
    Pages 533-542

  15. Particulate Suspensions as Contrast Media

    • M. R. Violante, H. W. Fischer
    Pages 543-576

  16. Appendix: Basics of Anesthesia for Experimental Animals

    • M. Sovak
    Pages 577-587

  17. Back Matter

    Pages 589-612
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Keywords

About this book

Contrast media are drugs by default. Had there been no default, there would be no need for a related pharmacology, and thus no need for this book. Radiographic contrast media (CM) are substances whose primary purpose is to enhance diagnostic information of medical imaging systems. The position of CM in pharmacology is unique. First, there is the unusual requirement of biological inertness. An ideal CM should be completely biologically inert, i.e., stable, not pharmacologically active, and efficiently and innocuously excretable. Because they fail to meet these requirements, CM must be considered drugs. The second unusual aspect of CM is that they are used in large quantities, their annual production being measured in tens of tons. It is not in spite of, but because of, the increased use of new radiographic systems, computed tomography, digital radiography, etc., that consumption is on the rise. And, it is not likely that the other emerging imaging modalities - NMR, ultrasonography, etc. - will displace radiographic CM soon; it is quite probable that these remarkable compounds will continue to play an active role in diagnostic imaging in the foreseeable future.

Editors and Affiliations

  • School of Medicine, Department of Radiology, S-009, University of California in San Diego, La Jolla, USA

    Milos Sovak

  • Biophysica Foundation, La Jolla, USA

    Milos Sovak

Bibliographic Information

  • Book Title: Radiocontrast Agents

  • Editors: Milos Sovak

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-642-69515-5

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1984

  • Softcover ISBN: 978-3-642-69517-9Published: 19 January 2012

  • eBook ISBN: 978-3-642-69515-5Published: 06 December 2012

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: XVI, 612

  • Topics: Pharmacology/Toxicology, Imaging / Radiology, Pharmacy

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