Skip to main content
SpringerLink
Log in
Book cover

Antimalarial Drug II

Current Antimalarial and New Drug Developments

  • Book
  • © 1984

Overview

Editors:
  1. Wallace Peters

    1. London School of Hygiene and Tropical Medicine, London, Great Britain

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. William H. G. Richards

    1. Wellcome Research Laboratories, Berkhamsted, Herts., Great Britain

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 68 / 2)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (16 chapters)

  1. Front Matter

    Pages I-XVIII
    Download chapter PDF

  2. Antimalarial Drugs in Current Use

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. 4-Aminoquinolines

      • E. W. McChesney, C. D. Fitch
      Pages 3-60

    3. Quinine and Quinine Analogues

      • W. Hofheinz, B. Merkli
      Pages 61-81

    4. 8-Aminoquinolines

      • P. E. Carson
      Pages 83-121

    5. Sulphonamides and Sulphones

      • H. J. Scholer, R. Leimer, R. Richle
      Pages 123-206

    6. Dihydrofolate Reductase Inhibitors

      • R. Ferone
      Pages 207-221

  3. Novel Methods of Drug Development

    1. Front Matter

      Pages 223-223
      Download chapter PDF

    2. Drug Combinations

      • W. Peters
      Pages 225-236

    3. Repository Preparations

      • D. F. Worth, L. M. Werbel
      Pages 237-252

    4. Cell Targeting of Primaquine

      • A. Trouet, P. Pirson, R. Baurain, M. Masquelier
      Pages 253-264

  4. Recent Developments in Antimalarials

    1. Front Matter

      Pages 265-265
      Download chapter PDF

    2. Drugs with Quinine-like Action

      • T. R. Sweeney
      Pages 267-324

    3. 8-Aminoquinolines

      • T. R. Sweeney
      Pages 325-342

    4. Lapinone, Menoctone, Hydroxyquinolinequinones and Similar Structures

      • A. T. Hudson
      Pages 343-361

    5. 4-Aminoquinolines and Mannich Bases

      • T. R. Sweeney, R. O. Pick
      Pages 363-385

    6. Triazines, Quinazolines and Related Dihydrofolate Reductase Inhibitors

      • P. Mamalis, L. M. Werbel
      Pages 387-442

    7. Antibiotics

      • K. H. Rieckmann
      Pages 443-470

    8. Miscellaneous Compounds

      • D. Warburton
      Pages 471-495

  5. Prevention of Drug Resistance

    1. Front Matter

      Pages 497-497
      Download chapter PDF
Back to top

Keywords

About this book

The construction of this volume has been guided by two personal convictions. Experience in the field of experimental chemotherapy, both in the pharmaceutical industry and academia, has convinced us that recent quantum technological advances in biochemistry, molecular biology, and immunology will permit and, indeed, necessitate an increasingly greater use of rational drug development in the future than has been the custom up to now. In Part l, therefore, we asked our contributors to provide detailed reviews covering the biology of the malaria parasites and their relation with their hosts, the experimental procedures including culture techniques that are necessary to take a drug from primary screening to clinical trial, and an account of antimalarial drug resistance. Our second conviction is that many research workers are all too loath to learn from the lessons of the past. For this reason we asked the contributors to Part 2 of this volume to review very thoroughly the widely scattered but voluminous literature on those few chemical groups that have provided the antimalarial drugs in clinical use at the present time. Much can be learned from the history of their development and the problems that have arisen with them in man. Some indeed may still have much to offer if they can be deployed in better ways than they are at present. This question has been taken up by several authors.

Editors and Affiliations

  • London School of Hygiene and Tropical Medicine, London, Great Britain

    Wallace Peters

  • Wellcome Research Laboratories, Berkhamsted, Herts., Great Britain

    William H. G. Richards

Bibliographic Information

  • Book Title: Antimalarial Drug II

  • Book Subtitle: Current Antimalarial and New Drug Developments

  • Editors: Wallace Peters, William H. G. Richards

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-642-69254-3

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1984

  • Softcover ISBN: 978-3-642-69256-7Published: 07 December 2011

  • eBook ISBN: 978-3-642-69254-3Published: 06 December 2012

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: XVIII, 520

  • Topics: Pharmacology/Toxicology, Medical Microbiology, Pharmacy

Publish with us

Policies and ethics

Back to top

Search

Navigation