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Allergic Reactions to Drugs

  • Book
  • © 1983

Overview

Editors:
  1. Alain L. Weck

    1. Institut für klinische Immunologie, Inselspital, Bern, Switzerland

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  2. Hans Bundgaard

    1. Department of Pharmaceutical Chemistry AD, The Royal Danish School of Pharmacy, Copenhagen, Denmark

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 63)

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Table of contents (27 chapters)

  1. Front Matter

    Pages I-XXXI
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  2. General Aspects of Drug Allergies

    1. Front Matter

      Pages 1-1
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    2. Immunochemical Basis of Allergic Reactions to Drugs

      • C. H. Schneider
      Pages 3-36

    3. Chemical and Pharmaceutical Aspects of Drug Allergy

      • H. Bundgaard
      Pages 37-74

    4. Immunopathological Mechanisms and Clinical Aspects of Allergic Reactions to Drugs

      • A. L. de Weck
      Pages 75-133

    5. Cutaneous Manifestations of Drug Allergy

      • K. H. Schulz
      Pages 135-162

    6. Allergy of the Respiratory Tract to Low Molecular Weight Chemical Agents

      • J. Pepys
      Pages 163-185

    7. Epidemiology of Drug Allergy: Drug Monitoring

      • R. Hoigné, F. Stocker, P. Middleton
      Pages 187-205

    8. Diagnostic Procedures in Drug Allergy

      • J.-P. Girard, S. Zawodnik
      Pages 207-225

    9. Prevention and Treatment of Drug Allergies

      • A. L. De Weck
      Pages 227-240

  3. Allergic Reactions to Specific Drugs

    1. Front Matter

      Pages 241-241
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    2. Major Drugs Acting on the Central Nervous System

      • C. W. Parker
      Pages 243-258

    3. General and Local Anaesthetics

      • E. S. K. Assem
      Pages 259-275

    4. Analgesics and Nonsteroidal Anti-Inflammatory Drugs

      • A. Szczeklik
      Pages 277-298

    5. Neuromuscular Blocking Drugs

      • E. S. K. Assem
      Pages 299-312

    6. Drugs Used Topically

      • K. E. Andersen, H. I. Maibach
      Pages 313-377

    7. Antihistamines

      • A. A. Fisher
      Pages 379-390

    8. Drugs Acting on the Cardiovascular System

      • H. E. Amos
      Pages 391-422

    9. Penicillins and Cephalosporins

      • A. L. de Weck
      Pages 423-482

    10. Other Antibiotics

      • D. Kraft
      Pages 483-520
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Keywords

About this book

According to most studies, allergic reactions represent 35%-50% of all untoward reactions to drugs, yet the pharmacological literature concerning the clinical aspects, diagnosis, and pathophysiological mechanisms of drug allergy is markedly less extensive than reports dealing with the toxicological or pharmacological effects of drugs. The main reasons for this state of affairs may be on the one hand that until a few years ago the pathophysiological mechanisms of the various types of allergic reactions were not well understood, and on the other hand that objective diagnosis of a drug allergy is still fraught with serious difficulties. Drug allergy is still an unpopular topic for most allergologists and pharmacologists; this is reflected by the fact that despite their frequency, allergic reactions to drugs still occupy a relatively small proportion of space in most pharmacology handbooks and in classical books devoted to the side effects of drugs. There has recently been considerable progress in research into the immunologi­ cal and pathophysiological events occurring in allergic reactions, and on that basis investigations of various drug allergies have also yield~d new objective findings. Consequently, it was natural to attempt a review of the most frequent and important drug allergies in the form of a handbook. We originally intended to present a comprehensive review of all drug allergies, but the realization of this goal soon became more difficult than we had at first imagined.

Editors and Affiliations

  • Institut für klinische Immunologie, Inselspital, Bern, Switzerland

    Alain L. Weck

  • Department of Pharmaceutical Chemistry AD, The Royal Danish School of Pharmacy, Copenhagen, Denmark

    Hans Bundgaard

Bibliographic Information

  • Book Title: Allergic Reactions to Drugs

  • Editors: Alain L. Weck, Hans Bundgaard

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-642-69088-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1983

  • Softcover ISBN: 978-3-642-69090-7Published: 10 December 2011

  • eBook ISBN: 978-3-642-69088-4Published: 06 December 2012

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: XXXII, 754

  • Topics: Pharmacology/Toxicology, Pharmacy

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