Gastric Cancer

1. Front Matter

   Pages I-XV

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2. Epidemiology and Pathogenesis

   1. Front Matter

      Pages 1-1

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   2. Exogenous Factors in the Epidemiology of Gastric Carcinoma

      • Carl J. Pfeiffer

      Pages 2-8

   3. Pathogenesis of Gastric Carcinoma: The Role of the Microenvironment

      • Pelayo Correa, Carlos Cuello, Guillermo Montes

      Pages 9-12

   4. Carcinoma of the Stomach in Urbanized Black South Africans

      • H. H. Lawson, I. Segal, L. Ou Tim

      Pages 13-14

   5. Carcinogenic Substances and Carcinogenesis — Their Clinical Significance

      • D. Schmähl

      Pages 15-18

3. Back Matter

   Pages 19-19

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4. Experimental Gastric Cancer

   1. Front Matter

      Pages 21-21

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   2. Experimental Gastric Cancer: Pathogenesis and Clinico-Histopathologic Correlation

      • Takao Saito, Osamu Sasaki, Tadakuni Matsukuchi, Masayoshi Iwamatsu, Kiyoshi Inokuchi

      Pages 22-31

   3. Epithelium at the Gastroenteral Borderline — Comparison of Animal Experiments and Clinical-Pathological Investigations

      • H. Meister, P. Schlag

      Pages 32-43

   4. Experimental Cancer of the Gastric Stump

      • K. Dahm, B. Werner, R. Eichen, H. Mitschke

      Pages 44-59

   5. Formal Pathogenesis of Chemically-Induced Cancers After Gastric Operation

      • F. Borchard

      Pages 60-63

   6. Vagotomy and Gastric Cancer

      • K. Junghanns, S. Ivankovic, R. M. Seufert, L. von Gerstenbergk

      Pages 64-66

   7. Susceptibility to Experimental Gastric Ulcer — Experimental Gastric Cancer, and Gastric Region

      • C. J. Pfeiffer

      Pages 67-68

5. Back Matter

   Pages 69-69

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6. Precancerous Lesions of Gastric Cancer

   1. Front Matter

      Pages 71-71

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   2. Histology of Possible Precancerous Stages in the Stomach

      • E. Grundmann, W. Schlake

      Pages 72-82

   3. Dysplastic Changes in Intestinal Metaplasia of the Gastric Mucosa

      • C. Cuello, P. Correa

      Pages 83-90

   4. Biological Significance of Dysplasias of the Epithelium and of Atrophic Gastritis

      • W. Oehlert

      Pages 91-104

   5. Significance and Location of Atrophic Gastritis and of Glandular Dysplasia in Benign and Malignant Gastric Disease

      • H. Meister, Ch. Holubarsch, O. Haferkamp, P. Schlag, Ch. Herfarth

      Pages 105-107

The problem of gastric cancer, with its multifaceted aspects, offers an example of diversified oncological research, which includes epidemiology, pathogenesis, histo­ morphology, surgical and conservative therapy in its spectrum. This disease not only constitutes an interesting and important subject for research, but it is also a challenge for the practitioner due to its inordinately poor prognosis. It therefore appeared a rewarding task to the editors to collect information from individual experts, in order to gain a topical summary of the problems pertaining to gastric cancer, as well as to provide a survey of the progress and the therapeutic possibilities in this field. This task was particularly enticing, as gastric cancer has lately come to belong to those tumors somewhat relegated to the shadows, although it is, despite its decreased fre­ quency in some western countries, still one of the most prevalent malignant diseases. This collection should emphasize the need for broadly based knowledge of individual problems as a prerequisite for any satisfactory therapy of an organ tumor. It is therefore the primary concern of this book to furnish anyone with an interest in oncology with this necessary survey. The editors thank Mrs. Karin Dohmeier and Mrs. Karin Kluge from Springer-Verlag for their cooperation in preparing this monograph. We extend our thanks to Mrs. Susanne Schenk and Mrs. Marga Wild, who contributed so much by her secretarial experience for the success of this volume. lJIm,September1979 Ch. Herfarth P. Schlag Table of Contents 1 Epidemiology and Pathogenesis . . . . . . . . . . .

• cancer
• carcinogenesis
• classification
• endoscopy
• epidemiology
• gastric cancer
• histology
• mortality
• nutrition
• oncology
• pathogenesis
• quality of life
• surgery
• therapy
• tumor

• Department für Chirurgie der Universität, Ulm, Federal Republic of Germany

  Christian H. Herfarth, Peter M. Schlag

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