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Cell death in the morphogenesis and teratogenesis of the heart

  • Book
  • © 1975

Overview

Authors:
  1. Tomas Pexieder

    1. Institut d’Histologie et d’Embryologie, Faculté de Médecine, Université de Lausanne, Lausanne, Suisse/Switzerland

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Part of the book series: Advances in Anatomy, Embryology and Cell Biology (ADVSANAT, volume 51/3)

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Table of contents (13 chapters)

  1. Front Matter

    Pages 1-5
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  2. Preface

    • Tomas Pexieder
    Pages 6-6

  3. Introduction

    • Tomas Pexieder
    Pages 7-9

  4. Bibliography Updating

    • Tomas Pexieder
    Pages 9-12

  5. Morphology of Cell Death

    • Tomas Pexieder
    Pages 12-17

  6. Topography of Cell Death in the Chick Embryo Heart

    • Tomas Pexieder
    Pages 17-19

  7. Comparative Topography of Cell Death Zones in Rat and Human Embryo Hearts

    • Tomas Pexieder
    Pages 19-24

  8. Ultrastructure of the Cell Death in Bulbar Cushions

    • Tomas Pexieder
    Pages 24-30

  9. Supravital Nile Blue Sulphate Staining in the Cell Death Studies

    • Tomas Pexieder
    Pages 31-37

  10. Cell Death and the Morphogenesis of the Heart

    • Tomas Pexieder
    Pages 37-47

  11. Interaction of Hemodynamics with the Cell Death Zones

    • Tomas Pexieder
    Pages 47-58

  12. Cell Death and Chemical Teratogenesis of the Heart

    • Tomas Pexieder
    Pages 58-72

  13. Conclusion

    • Tomas Pexieder
    Pages 72-74

  14. Summary

    • Tomas Pexieder
    Pages 74-76

  15. Back Matter

    Pages 76-100
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Keywords

About this book

In spite of the continuing progress of research in the fields of cellular and molecular biology, which has oriented many embryologists towards molecular biology, no concrete explanation of morphogenesis has yet been found. The present state of knowledge of heart development is characterized by an enormous discrepancy between the qualitative descriptions of what happens on the organ level and the more or less quantitative information on subcellular and molecular events. It is generally not understood how cells form tissues and how tissues generate particular forms of an organ. In an attempt to fill the gaps we systematically studied in the period 1968 to 1973 one of the general but rather neglected morphogenetic mechanisms which integrates cells into tissues and organs-cell death. Only a small part of our research on cell death in the development of chick, rat and human embryo hearts has as yet been published in extenso. Most of it has been communicated in papers delivered at different scientific meetings. We would like to use the opportunity offered by Advances to present a syn­ thesis and integrative review of our results. In this way the actual period of discovery of the existence of cell death and of its morphogenetic role in the heart development come to an end. This opens up the next phase of our research which consists in studies of how cell death is integrated with other morphogenetic mechanisms.

Authors and Affiliations

  • Institut d’Histologie et d’Embryologie, Faculté de Médecine, Université de Lausanne, Lausanne, Suisse/Switzerland

    Tomas Pexieder

Bibliographic Information

  • Book Title: Cell death in the morphogenesis and teratogenesis of the heart

  • Authors: Tomas Pexieder

  • Series Title: Advances in Anatomy, Embryology and Cell Biology

  • DOI: https://doi.org/10.1007/978-3-642-66142-6

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 1975

  • Softcover ISBN: 978-3-540-07270-6Published: 16 June 1975

  • eBook ISBN: 978-3-642-66142-6Published: 06 December 2012

  • Series ISSN: 0301-5556

  • Series E-ISSN: 2192-7065

  • Edition Number: 1

  • Number of Pages: 100

  • Number of Illustrations: 18 b/w illustrations

  • Topics: Medicine/Public Health, general

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