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Molecular and Cellular Mechanisms in Disease

1: Bioenergetics · Cell Specificity · Inborn Errors of Metabolism · Malnutrition · Calcium and Phosphorus Iron and Bile Pigments · Coagulopathies · Hormones Body Fluids and Electrolytes

  • Textbook
  • © 1976

Overview

Authors:
  1. Julien L. Lancker

    1. Department of Pathology, U.C.L.A. School of Medicine, Los Angeles, USA

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Table of contents (9 chapters)

  1. Front Matter

    Pages I-XV
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  2. Cellular Sources of Energy

    • Julien L. Van Lancker
    Pages 1-70

  3. Determination of Cellular Specificity

    • Julien L. Van Lancker
    Pages 71-141

  4. Inborn Errors of Metabolism

    • Julien L. Van Lancker
    Pages 143-244

  5. Malnutrition

    • Julien L. Van Lancker
    Pages 245-330

  6. Calcium and Phosphorus Metabolism

    • Julien L. Van Lancker
    Pages 331-359

  7. Iron and Bile Pigment Metabolism

    • Julien L. Van Lancker
    Pages 361-395

  8. Blood Coagulation

    • Julien L. Van Lancker
    Pages 397-422

  9. Hormones

    • Julien L. Van Lancker
    Pages 423-536

  10. Alterations of Body Fluids and Electrolyte Metabolism

    • Julien L. Van Lancker
    Pages 537-603

  11. Back Matter

    Pages 605-632
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Keywords

About this book

In spite of ingenious experiments, imaginative theories, and unshakable faith in supreme forces, there is no way to know how life began. What is certain is that in the course of the development of the universe existing sources of energy fused to generate atoms, and atoms mingled to become small molecules. At some point by chance or design-according to one's belief, but no one's evidence-small molecules such as hydrogen, oxygen, carbon dioxide, water, and ammonia reacted to yield larger molecules with the property most essential to life: self-replication. Such molecules had to achieve a proper balance between the stability needed for their survival in the environment and the mutability for the generation of many forms of life. How amino acids were created or how DNA, RNA, and proteins developed remains a mystery. But we know that a simple core of nucleic acid embedded in a protein coat made the simplest unit of life (except for viroids). Whether viruses are a primitive or degenerated form of life is not known. Once proteins appeared, their great structural plasticity allowed them to react with other elements such as sulfur, iron, copper, and zinc. After an incalculable number of years, some of the proteins became capable of catalyzing the synthesis of new nucleic acids, new proteins, and other compounds such as polysaccharides and lipids.

Authors and Affiliations

  • Department of Pathology, U.C.L.A. School of Medicine, Los Angeles, USA

    Julien L. Lancker

Bibliographic Information

  • Book Title: Molecular and Cellular Mechanisms in Disease

  • Book Subtitle: 1: Bioenergetics · Cell Specificity · Inborn Errors of Metabolism · Malnutrition · Calcium and Phosphorus Iron and Bile Pigments · Coagulopathies · Hormones Body Fluids and Electrolytes

  • Authors: Julien L. Lancker

  • DOI: https://doi.org/10.1007/978-3-642-65967-6

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1976

  • Softcover ISBN: 978-3-642-65969-0Published: 15 November 2011

  • eBook ISBN: 978-3-642-65967-6Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XLII, 604

  • Topics: Life Sciences, general, Biomedicine general

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