Cerebral Circulation and Metabolism

1. Front Matter

   Pages i-xxviii

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2. Autoregulation

   1. Front Matter

      Pages 1-1

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   2. The Lower and Upper Limits for Autoregulation of Cerebral Blood Flow

      • S. Strandgaard, D. Sengupta, E. T. Mackenzie, J. O. Rowan, J. Olesen, E. Skinhøj et al.

      Pages 3-6

   3. Acute Arterial Hypertension and the Blood-Brain Barrier: An Experimental Study in Dogs

      • B. Ekström-Jodal, E. Häggendal, B. Johansson, L.-E. Linder, N. J. Nilsson

      Pages 7-9

   4. Effects of Local Increases of Venous Pressure on Canine Cerebral Hemodynamics

      • T. E. Emerson Jr., J. L. Parker

      Pages 10-13

   5. The Effect of Lowered Cardiac Output on Cerebral Blood Flow

      • H. Rappaport, D. Bruce, T. Langfitt

      Pages 14-17

   6. Autoregulation of Cerebral Blood Flow During Controlled Hypotension

      • W. Fitch, G. G. Ferguson, D. Sengupta, J. Garibi

      Pages 18-20

   7. Cerebral Blood Flow Autoregulation, Cerebrospinal Fluid Acid-Base Parameters, and Profound Hypotension Induced by Sodium Nitroprusside and Deep Halothane Anesthesia

      • N. P. Keaney, D. G. McDowall, J. M. Turner, J. R. Lane, Y. Okuda, V. W. A. Pickerodt et al.

      Pages 21-23

   8. Correlation of Regional Cerebral Blood Volume with PaCO2 and Arterial Blood Pressure

      • M. E. Phelps, R. L. Grubb Jr., M. E. Raichle, M. M. Ter-Pogossian

      Pages 24-26

   9. Cerebral Blood Flow and Metabolism with Regard to Autoregulation in Cerebral Perfusion Pressure Experiments

      • S. Hoyer, J. Hamer, E. Alberti, H. Stoeckel, F. Weinhardt

      Pages 27-29

3. Back Matter

   Pages 30-31

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4. Chemical Control

   1. Front Matter

      Pages 33-33

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   2. The Effect of Metabolic Alkalosis on Cerebral Blood Flow in Man

      • J. R. Harp, B. B. Gutsche, E. M. Kennell, J. L. Neigh, E. Stromberg, H. Wollman

      Pages 35-37

   3. Circulation to the Brain of Rats During Acute and Prolonged Hypercapnia and Hypocapnia

      • J. L. Pannier, I. Leusen

      Pages 38-40

   4. Primate Pial Arterial Pressure Responses to Changes in Inspired CO2 and Systemic Arterial Pressure

      • J. R. Fox, D. D. Stromberg

      Pages 41-42

   5. Dual Control of Cerebral Circulation: Separate Sites of Action in Vascular Tree in Autoregulation and Chemical Control

      • F. Gotoh, F. Muramatsu, Y. Fukuuchi, T. Amano

      Pages 43-45

   6. Interdependence of Capillary Flow and Regional Blood Flow of the Brain

      • E. Leniger-Follert, D. W. Lübbers

      Pages 46-48

   7. Interactions of Ionic Mechanisms in the Regulation of the Resistance of Pial Vessels

      • E. Betz, H. G. Enzenross, V. Vlahov

      Pages 49-51

   8. The Effect of Local Changes in Bicarbonate and Potassium Concentration on Hypothalamic Blood Flow

      • J. Caronna, I. R. Cameron

      Pages 52-54

   9. Cerebral Hemodynamics: The Effect of Hypoxia on Autoregulation and CO2 Reactivity

      • B. M. Bloor

      Pages 55-58

This volume contains the papers presented at cluded are the concluding remarks made by the the Sixth International Symposium on Cerebral chairman of each session. The last session con­ Blood Flow held in Philadelphia on June 6-9, tains discussions of several topics which were felt to be of sufficient importance and interest to 1973. Since the first meeting on cerebral blood flow, held in Lund in 1964, the number of par­ warrant extended consideration. These con­ ticipants in these symposia has steadily increased cerned the questions of neurogenic control of until at this meeting it was necessary to conduct the cerebral circulation, the role of failure of simultaneous sessions. The interest and effort reperfusion in cerebral ischemia, and a discus­ sion of invasive and noninvasive methods of directed toward problems concerned with cere­ bral circulation and metabolism, as well as the CBF determination. Owing to the large number increasing sophistication applied to these prob­ of papers included in this book and the interests lems, are amply demonstrated in this book. of rapid publication, it was not possible to in­ A wide variety of topics was discussed at the clude the discussions of each paper. The orga­ symposium with major emphasis on the basic nizers regret the necessity of this decision but aspects of the control of cerebral circulation and wish to thank the many participants who con­ metabolism.

• anesthesia
• aneurysm
• brain
• brain injury
• brain tumor
• cerebral ischemia
• circulation
• depression
• electroencephalography (EEG)
• epilepsy
• hypoxia
• intracranial pressure
• schizophrenia
• trauma
• tumor

• Div. of Neurosurgery, Univ. of Pennsylvania, Philadelphia, USA

  Thomas W. Langfitt

• Dept. of Radiology, Philadelphia General Hospital, Philadelphia, USA

  Lawrence C. McHenry

• Cerebrovascular Research Center, Univ. Pennsylvania, Philadelphia, USA

  Martin Reivich

• Dept. of Anesthesia, Hospital of the Univ. Pennsylvania, Philadelphia, USA

  Harry Wollman

Policies and ethics