Central Nervous System

1. Front Matter

   Pages I-VIII

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2. Biochemical Analysis of Metabolic Pathways

   1. Front Matter

      Pages 1-1

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   2. Adenosine in Neurohumoral and Regulatory Roles in the Brain

      • H. McIlwain

      Pages 3-11

   3. Lipid Metabolism and its Regulation in Brain Tissue

      • G. Porcellati

      Pages 12-20

   4. Choline and its Metabolic Successors in Brain

      • H. Kewitz, K. Dross, O. Pleul

      Pages 21-32

   5. Structural and Functional Significance of Brain Glycoproteins

      • C. Di Benedetta

      Pages 33-40

   6. Antimetabolic Action on the Pentose Phosphate Pathway in the Central Nervous System Induced by 6-Aminonicotinamide

      • H. Herken, K. Lange, H. Kolbe, K. Keller

      Pages 41-54

   7. Studies of Flux Rates at the Glucose 6-Phosphate Crossover

      • K. Lange, K. Keller, H. Kolbe

      Pages 55-62

   8. Purification and Regulation of Phosphate-Activated Pig Brain Glutaminase

      • E. Kvamme, G. Svenneby, I. Aa Torgner

      Pages 63-69

   9. Functional Aspects of Nucleic Acid Metabolism in Brain

      • A. Giuditta

      Pages 70-77

   10. Uptake and Action of Glycine in Cultures of Central Nervous Tissue from Rat

       • L. Hösli, E. Hösli, P. F. Andrès

       Pages 78-83

   11. Neuronal Activity and Axonal Flow

       • G. W. Kreutzberg, P. Schubert

       Pages 84-93

   12. Intra-Axonal Transport of Young Amine Granules: Implications for Nerve-Terminal Function

       • A. Dahlström, J. Häggendal

       Pages 94-103

   13. The Application of Micromethods to Neurochemistry

       • V. Neuhoff

       Pages 104-114

   14. Serum as Medium for Brain and Other Tissues Respiring in vitro

       • M. Sangiovanni, A. Fossati, G. B. Gervasi, F. Scrollini, S. Ferri, E. Gori

       Pages 115-118

3. Membrane Function and Neurotransmission

   1. Front Matter

      Pages 119-119

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   2. Importance of Structure and Organization for the Chemical Reactions in Excitable Membranes

      • David Nachmansohn

      Pages 121-137

   3. Allostery and Permeability of Cellular Membranes

      • E. Schoffeniels

      Pages 138-146

   4. Release of 3H-Acetylcholine and 3H-Choline from the Cerebral Cortex of the Rat Following Administration of 3H-Choline

      • G. Pepeu, F. Crabai, A. Mulas, M. L. Mulas

      Pages 147-152

   5. Changes in the Enzymes for the Metabolism of Acetylcholine During Development of the Central Nervous System

      • G. Giacobini, G. Filogamo

      Pages 153-157

This book is based on the Symposium "Metabolic Regulation and Functional Activity in the Central Nervous System" which was held on September 16 and 17, 1972, at Saint­ Vincent (Aosta)/Italy, and was sponsored by the Accademia di Medicina di Torino with the scientific cooperation of the Istituto di Farmacologia, Universita di Torino, and the Pharmakologisches Institut der Freien Universitat Berlin. Its purpose was to give a greater number of scientists from different countries an opportunity to report their latest results under a heading concerning general relationships between metabolism and function. We quite deliberately refrained from pursuing the partly heterogenous subjects into details. Thus, the organizers hoped to be able to interest a greater circle of readers for the manifold subjects from various fields dealing with the investigation of metabolic processes in the central nervous system. The discussion remarks to the lectures could not be considered for printing. The Accademia di Medicina di Torino and all others concerned do not only thank Dr. R. Di Carlo and other members of the Istituto di Farmacologia, Universita di Torino, for the excellent work they performed in preparing this Symposium, but also the Amministrazione Regionale della Valle di Aosta and SIT A V di Saint-Vincent for their generous support and their kind hospitality which made the stay at Saint-Vincent most agreeable for all participants.

• adenosine
• brain
• central nervous system
• cortex
• hospital
• metabolism
• nervous system
• neurochemistry
• pharmacology
• regulation
• relationships
• metabolic disease

• Institute of Pharmacology, University of Turin, Turin, Italy

  E. Genazzani

• Pharmakologisches Institut, Freien Universität Berlin, Berlin 33, Germany

  H. Herken

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