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Antiepileptic Drugs

Pharmacology and Therapeutics

  • Book
  • © 1999

Overview

Editors:
  1. Mervyn J. Eadie

    1. Departments of Medicine, Royal Brisbane Hospital, University of Queensland, Herston, Australia

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    You can also search for this editor in PubMed   Google Scholar

  2. Frank J. E. Vajda

    1. Australian Centre for Clinical Neuropharmacology, St. Vincent’s Hospital, Fitzroy, Australia

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 138)

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Table of contents (23 chapters)

  1. Front Matter

    Pages I-XXXVIII
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  2. Classification of Epileptic Seizures and the Epilepsies and Drugs of Choice for Their Treatment

    • F. E. Dreifuss, N. B. Fountain
    Pages 1-17

  3. Animal Models of Epilepsy and Epileptic Seizures

    • W. Löscher
    Pages 19-62

  4. Epileptogenesis: Electrophysiology

    • J. O. Willoughby
    Pages 63-85

  5. Epileptogenesis: Biochemical Aspects

    • B. Jarrott
    Pages 87-121

  6. Cellular Actions of Antiepileptic Drugs

    • R. L. Macdonald
    Pages 123-150

  7. The Search for New Anticonvulsants

    • D. Schmidt
    Pages 151-172

  8. Measurement of Anticonvulsants and Their Metabolites in Biological Fluids

    • W. D. Hooper, L. P. Johnson
    Pages 173-187

  9. Older Anticonvulsants Continuing in Use but with Limited Advance in Knowledge

    • M. J. Eadie, F. J. E. Vajda
    Pages 189-228

  10. Phenytoin and Congeners

    • H. Kutt, C. L. Harden
    Pages 229-265

  11. Carbamazepine

    • R. G. Dickinson, M. J. Eadie, E. J. E. Vajda
    Pages 267-317

  12. Oxcarbazepine

    • S. C. Schachter
    Pages 319-330

  13. Lamotrigine

    • M. C. Walker, J. W. A. S. Sander
    Pages 331-358

  14. Valproate

    • D. D. Shen, R. H. Levy
    Pages 359-373

  15. Vigabatrin

    • E. Ben-Menachem
    Pages 375-394

  16. Benzodiazepines

    • C. Kilpatrick
    Pages 395-423

  17. Gabapentin

    • F. J. E. Vajda
    Pages 425-446

  18. Tiagabine

    • S. C. Schachter
    Pages 447-463

  19. Topiramate

    • D. Heaney, S. Shorvon
    Pages 465-484

  20. Zonisamide

    • I. E. Leppik
    Pages 485-498
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Keywords

About this book

In 1985, volume 74 of the Springer-Verlag Handbook of Experimental Phar­ macology, under the editorship of H. -H. Frey and D. Janz, appeared. In this volume the then available data on the topic of antiepileptic drugs were col­ lated and analysed. Over the intervening years knowledge in this area has grown progressively. More new antiepileptic drugs than the total number of agents that were in common use 15 years ago have in the interval either come on to the market or are about to do so. As well, further agents are at a fairly advanced stage of development, whilst the already established drugs have by and large held their places in clinical practice. Knowledge of epileptogenesis has advanced considerably. The mechanisms of action of antiepileptic drugs at the molecular level and in various animal models of epileptic seizures and of the epileptic state are much better understood than they were previously. As well, more information is available concerning the natural history of human epilepsy, and this knowledge is important in making optimal use of the various agents that are now available. Therefore, it has seemed appropriate at this stage in the evolution of knowledge to produce a second volume dealing with Antiepileptic Drugs in the Handbook of Experimental Pharmacology series.

Editors and Affiliations

  • Departments of Medicine, Royal Brisbane Hospital, University of Queensland, Herston, Australia

    Mervyn J. Eadie

  • Australian Centre for Clinical Neuropharmacology, St. Vincent’s Hospital, Fitzroy, Australia

    Frank J. E. Vajda

Bibliographic Information

  • Book Title: Antiepileptic Drugs

  • Book Subtitle: Pharmacology and Therapeutics

  • Editors: Mervyn J. Eadie, Frank J. E. Vajda

  • Series Title: Handbook of Experimental Pharmacology

  • DOI: https://doi.org/10.1007/978-3-642-60072-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1999

  • Softcover ISBN: 978-3-642-64244-9Published: 22 September 2011

  • eBook ISBN: 978-3-642-60072-2Published: 06 December 2012

  • Series ISSN: 0171-2004

  • Series E-ISSN: 1865-0325

  • Edition Number: 1

  • Number of Pages: XXXVIII, 631

  • Topics: Pharmacology/Toxicology, Neurosciences, Neurology

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