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The Hepatitis C Viruses

  • Book
  • © 2000

Overview

Editors:
  1. Curt H. Hagedorn

    1. Division of Digestive Diseases and Genetics — Winship Cancer Center, Emory University School of Medicine, Atlanta, USA

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  2. Charles M. Rice

    1. Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 242)

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Table of contents (16 chapters)

  1. Front Matter

    Pages I-IX
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  2. Studies of Non-A, Non-B Hepatitis and Characterization of the Hepatitis C Virus in Chimpanzees

    • D. W. Bradley
    Pages 1-23

  3. Hepatitis C Epidemiology

    • D. L. Thomas
    Pages 25-41

  4. Natural History and Disease Manifestations of Hepatitis C Infection

    • D. Theodore, M. W. Fried
    Pages 43-54

  5. Overview of Hepatitis C Virus Genome Structure, Polyprotein Processing, and Protein Properties

    • K. E. Reed, C. M. Rice
    Pages 55-84

  6. Internal Ribosome Entry Site-Mediated Translation in Hepatitis C Virus Replication

    • R. C. A. Rijnbrand, S. M. Lemon
    Pages 85-116

  7. Hepatitis C Virus Core Protein: Possible Roles in Viral Pathogenesis

    • M. M. C. Lai, C. F. Ware
    Pages 117-134

  8. Folding, Assembly and Subcellular Localization of Hepatitis C Virus Glycoproteins

    • J. Dubuisson
    Pages 135-148

  9. Structure and Function of the Hepatitis C Virus NS3-NS4A Serine Proteinase

    • R. De Francesco, C. Steinkühler
    Pages 149-169

  10. Structure and Function of Hepatitis C Virus NS3 Helicase

    • A. D. Kwong, J. L. Kim, C. Lin
    Pages 171-196

  11. Evading the Interferon Response: Hepatitis C Virus and the Interferon-Induced Protein Kinase, PKR

    • M. J. Korth, M. G. Katze
    Pages 197-224

  12. Hepatitis C Virus RNA-Dependent RNA Polymerase (NS5B Polymerase)

    • C. H. Hagedorn, E. H. van Beers, C. De Staercke
    Pages 225-260

  13. Systems to Culture Hepatitis C Virus

    • N. Kato, K. Shimotohno
    Pages 261-278

  14. Characterization of Hepatitis C Virus Infectious Clones in Chimpanzees: Long-Term Studies

    • M. E. Major, S. M. Feinstone
    Pages 279-298

  15. Cell Mediated Immune Response to the Hepatitis C Virus

    • B. Rehermann, F. V. Chisari
    Pages 299-325

  16. Strategies and Prospects for Vaccination Against the Hepatitis C Viruses

    • M. Houghton
    Pages 327-339

  17. The GB Agent

    • J. N. Simons, S. M. Desai, I. K. Mushahwar
    Pages 341-375

  18. Back Matter

    Pages 377-384
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Keywords

About this book

Chronic hepatitis C is a major worldwide health problem affecting more than 170 million people. Chronic infections lead to cirrhosis and liver failure or hepatocellular cancer in many instances. This volume includes comprehensive reviews that cover much of the vast literature that has appeared since the identification of the hepatitis C virus RNA genome. It will be an invaluable collection for anyone wanting an up-to-date picture of HCV transmission, molecular virology, immune response, cellular/molecular pathogenesis, and possible avenues for developing effective new therapeutics and vaccines.

Editors and Affiliations

  • Division of Digestive Diseases and Genetics — Winship Cancer Center, Emory University School of Medicine, Atlanta, USA

    Curt H. Hagedorn

  • Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, USA

    Charles M. Rice

Bibliographic Information

  • Book Title: The Hepatitis C Viruses

  • Editors: Curt H. Hagedorn, Charles M. Rice

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-59605-6

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2000

  • Softcover ISBN: 978-3-642-64047-6Published: 21 September 2011

  • eBook ISBN: 978-3-642-59605-6Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: IX, 391

  • Number of Illustrations: 4 illustrations in colour

  • Topics: Virology, Immunology, Biochemistry, general, Pharmacology/Toxicology, Internal Medicine

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