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Lymphatic Metastasis and Sentinel Lymphonodectomy

  • Conference proceedings
  • © 2000

Overview

Editors:
  1. Peter M. Schlag

    1. Klinik für Chirurgie und chirurgische Onkologie Robert-Rössle-Klinik, Universitätsklinikum Charité, Berlin, Germany

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    You can also search for this editor in PubMed   Google Scholar

  2. Umberto Veronesi

    1. Istituto Europeo di Oncologia, Milano, Italy

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 157)

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Table of contents (26 papers)

  1. Front Matter

    Pages I-XII
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  2. Clinical Assessment of Lymph Node Metastases

    1. Front Matter

      Pages 1-1
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    2. Efficacy of Immunoscintigraphy for Detection of Lymph Node Metastases

      • K. E. Britton, H. Jan, A. R. Al-Yasi, L. Biassoni, M. J. Carroll, M. Granowska
      Pages 3-11

    3. Sensitivity and Specificity of Positron Emission Tomography (PET) for the Diagnosis of Lymph Node Metastases

      • L. G. Strauss
      Pages 12-19

    4. Diagnosis and Staging of Lymph Node Metastasis

      • Ch. Wittekind
      Pages 20-28

    5. Detection and Relevance of Immunohistochemically Identifiable Tumor Cells in Lymph Nodes

      • B. Passlick, K. Pantel
      Pages 29-37

  3. Principles of Lymphatic Metastasis

    1. Front Matter

      Pages 39-39
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    2. Cell Biology of Lymphatic Metastasis The Potential Role of c-erbB Oncogene Signalling

      • S. A. Eccles
      Pages 41-54

    3. The Lymph Node as a Bridgehead in the Metastatic Dissemination of Tumors

      • J. P. Sleeman
      Pages 55-81

    4. Functional Anatomy of Lymphatic Vessels Under the Aspect of Tumor Invasion

      • A.-A. Duenne, J. A. Werner
      Pages 82-89

    5. Molecular Diagnosis of Head and Neck Cancer

      • V. M. M. van Houten, M. W. M. van den Brekel, F. Denkers, D. R. Colnot, J. Westerga, P. J. van Diest et al.
      Pages 90-106

  4. Principles of Lymphatic Mapping and Sentinel Node Detection

    1. Front Matter

      Pages 107-107
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    2. The Concept of the Sentinel Lymph Node

      • R. M. Cabanas
      Pages 109-120

    3. Sentinel Node Localization by Lymphoscintigraphy: A Reliable Technique with Widespread Applications

      • G. Paganelli, C. De Cicco, M. Chinol
      Pages 121-129

    4. Vital Dye and Radiolabelled Colloids — Complement or Alternative

      • R. Pijpers, P. J. Borgstein, G. J. J. Teule, S. Meijer
      Pages 130-137

  5. Sentinel Node Detection in Urogenital Cancer

    1. Front Matter

      Pages 139-139
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    2. Application of the Sentinel Node Concept in Urogenital Cancer

      • R. M. Cabanas
      Pages 141-149

    3. Intraoperative Lymphatic Mapping and Sentinel Node Identification: Gynecologic Applications

      • C. Levenback
      Pages 150-158

  6. Sentinel Node Detection in Malignant Melanoma

    1. Front Matter

      Pages 159-159
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    2. Sentinel Node Detection in Malignant Melanoma

      • A. D. Chan, D. L. Morton
      Pages 161-177
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Keywords

About this book

Metastases determine malignancy. The main attention so far has been focused upon organ metastases. The molecular mechanisms thereof, while far from being totally elucidated, are increasingly well understood. Modern diagnostic tools now enable detection and precise localization of small lesions. In contrast, our knowl­ edge and diagnostic capabilities regarding metastatic spread to the'lymphatic system are rather limited. However, there have re­ cently been a number of interesting advances. It is the aim of this volume to submit these developments to detailed analysis. The therapeutic relevance of enhanced sensitivity in detection of lymph node metastases has to be considered in the light of in­ creased morbidity versus eventual prognostic improvements by modification of therapy. An interesting concept which might im­ prove diagnostic accuracy while reducing operative morbidity is the "sentinel node" technique. Surgical standards are lacking, however, and many fundamental questions pertaining to precise lymphatic mapping remain unanswered. Whether the sentinel node concept is of general relevance or whether it is applicable in only a few organs remains to be determined. This book offers intensive discussion of the concept from methodological and tu­ mor biological viewpoints. World-renowned experts with long­ term involvement in related basic and clinical research provide the reader with a broad survey of actual knowledge together with a critical appraisal of recent and future developments. We sincerely hope this book succeeds in providing an outlook as a reference for all clinicians on future prospects and serving and researchers in this extremely important field.

Editors and Affiliations

  • Klinik für Chirurgie und chirurgische Onkologie Robert-Rössle-Klinik, Universitätsklinikum Charité, Berlin, Germany

    Peter M. Schlag

  • Istituto Europeo di Oncologia, Milano, Italy

    Umberto Veronesi

Bibliographic Information

  • Book Title: Lymphatic Metastasis and Sentinel Lymphonodectomy

  • Editors: Peter M. Schlag, Umberto Veronesi

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-642-57151-0

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin · Heidelberg 2000

  • Hardcover ISBN: 978-3-540-66642-4Published: 10 May 2000

  • Softcover ISBN: 978-3-642-63070-5Published: 21 October 2012

  • eBook ISBN: 978-3-642-57151-0Published: 06 December 2012

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: XII, 309

  • Number of Illustrations: 61 b/w illustrations, 2 illustrations in colour

  • Topics: Cancer Research, Oncology, General Surgery, Dermatology, Nuclear Medicine, Pathology

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