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Jaagsiekte Sheep Retrovirus and Lung Cancer

  • Book
  • © 2003

Overview

Editors:
  1. Hung Fan

    1. Cancer Research Institute, University of California, Irvine, Irvine, USA

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Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 275)

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Table of contents (9 chapters)

  1. Front Matter

    Pages I-XI
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  2. A History of Ovine Pulmonary Adenocarcinoma (Jaagsiekte) and Experiments Leading to the Deduction of the JSRV Nucleotide Sequence

    • D. F. York, G. Querat
    Pages 1-23

  3. Pathology of Ovine Pulmonary Adenocarcinoma

    • M. De Las Heras, L. González, J. M. Sharp
    Pages 25-54

  4. Natural History of JSRV in Sheep

    • J. M. Sharp, J. C. DeMartini
    Pages 55-79

  5. Molecular Biology of Jaagsiekte Sheep Retrovirus

    • M. Palmarini, H. Fan
    Pages 81-115

  6. Endogenous Retroviruses Related to Jaagsiekte Sheep Retrovirus

    • J. C. DeMartini, J. O. Carlson, C. Leroux, T. Spencer, M. Palmarini
    Pages 117-137

  7. Transformation and Oncogenesis by Jaagsiekte Sheep Retrovirus

    • H. Fan, M. Palmarini, J. C. DeMartini
    Pages 139-177

  8. Identification of Hyal2 as the Cell-Surface Receptor for Jaagsiekte Sheep Retrovirus and Ovine Nasal Adenocarcinoma Virus

    • A. D. Miller
    Pages 179-199

  9. Enzootic Nasal Adenocarcinoma of Sheep and Goats

    • M. De las Heras, A. Ortín, C. Cousens, E. Minguijón, J. M. Sharp
    Pages 201-223

  10. Pathology of Human Bronchioloalveolar Carcinoma and Its Relationship to the Ovine Disease

    • J.-F. Mornex, F. Thivolet, M. De Las Heras, C. Leroux
    Pages 225-248

  11. Back Matter

    Pages 249-252
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Keywords

About this book

Retroviruses have been of great importance to biomedical science for the past half century. Initially, studies on oncogenic animal retroviruses provided important insights into molecular processes in carcinogenesis – most notably the existence and mechanisms of action of oncogenes and proto-oncogenes. Moreover, several human diseases are caused by retroviruses, including AIDS, adult T-cell leukemia and the neurological disease HAM/TSP. The topic of this volume is a relatively unknown animal retrovirus, jaagsiekte sheep retrovirus, the causative agent of transmissible lung cancer in sheep –ovine pulmonary adenocarcinoma. The disease was first documented in South Africa in the 1800s, it has a wide geographical distribution, and it is of economic importance in high endemic regions. However, until very recently the nature of the etiologic agent was unclear, and relatively few laboratories actively studied the disease.

Editors and Affiliations

  • Cancer Research Institute, University of California, Irvine, Irvine, USA

    Hung Fan

Bibliographic Information

  • Book Title: Jaagsiekte Sheep Retrovirus and Lung Cancer

  • Editors: Hung Fan

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-55638-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2003

  • Hardcover ISBN: 978-3-540-44096-3Published: 13 December 2002

  • Softcover ISBN: 978-3-642-62897-9Published: 03 October 2013

  • eBook ISBN: 978-3-642-55638-8Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: XI, 254

  • Topics: Virology

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