Skip to main content
SpringerLink
Log in

Inhalation Toxicology

The Design and Interpretation of Inhalation Studies and Their Use in Risk Assessment

  • Conference proceedings
  • © 1988

Overview

Editors:
  1. Donald L. Dungworth

    1. Department of Veterinary Pathology, University of California, Davis, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Georg Kimmerle

    1. Bayer AG, Institute for Toxicology, Wuppertal-Elberfeld, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  3. James Lewkowski

    1. Abbott Laboratories, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  4. Roger O. McClellan

    1. Inhalation Toxicology Research Institute, Lovelace Biomedical and Environmental Research Institute, Albuquerque, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  5. Werner Stöber

    1. Fraunhofer Institute of Toxicology and Aerosol Research, Hannover 61, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: ILSI Monographs (ILSI MONOGRAPHS)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (19 papers)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  3. Methodological Issues in Designing and Conducting Studies with Laboratory Animals

    1. Front Matter

      Pages 66-66
      Download chapter PDF

    2. Exposure Facilities and Aerosol Generation and Characterization for Inhalation Experiments

      • W. Holländer
      Pages 67-85

    3. Different Methods Used in Acute and Subchronic Inhalation Studies of Potential Lung Irritants, with Particular Attention to Lung Function Measurements

      • J. Pauluhn
      Pages 87-101

    4. Chronic Inhalation Toxicity Studies: Protocols and Pitfalls

      • P. E. Morrow, R. Mermelstein
      Pages 103-117

    5. Carcinogenicity Protocols

      • R. A. Griesemer
      Pages 119-137

  4. Interpretation of Toxicokinetic Studies with Airborne Toxicants

    1. Front Matter

      Pages 138-138
      Download chapter PDF

    2. Interspecies Dosimetry of Reactive Gases

      • F. J. Miller, J. H. Overton, T. R. Gerrity, R. C. Graham
      Pages 139-155

    3. Behavior of Inspired Aerosol Boli in Humans

      • J. Heyder
      Pages 157-167

    4. Respiratory Tract Clearance of Particles and Substances Dissociated from Particles

      • R. G. Cuddihy, H. C. Yeh
      Pages 169-193
Back to top

Keywords

About this book

The International Life Sciences Institute (ILSI), a nonprofit, public foundation, was established in 1978 to advance the sciences of nutrition, toxicology, and food safety. ILSI promotes the resolution of health and safety issues in these areas by sponsoring research, conferences, publications, and educational programs. Through ILSI's programs, scientists from government, academia, and industry unite their efforts to resolve issues of critical importance to the public. As part of its commitment to understanding and resolving health and safety issues, ILSI is pleased to sponsor this series of monographs that consolidates new scientific knowledge, defines research needs, and provides a background for the effective application of scientific advances in toxicology and food safety. Alex Malaspina President International Life Sciences Institute Contents Series Foreword . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . xi Part I. Approaches to Assessing the Toxicity of Airborne Toxicants Chapter 1. Standard-Setting as an Integrative Exercise: Alchemy, Juggling, or Science? . . . . . . . . . . . . . . . . . . . . . . . 1 D. v. Bates Chapter 2. Species Differences in Inhalation Toxicology: Variations in Exposure-Dose Relationships and Macrophage Function. . . . . . . . . . . . . . . . . . . . . . . . . . . . 11 J. D. Brain Chapter 3. Cell Populations of the Respiratory System: Interspecies Diversity in Composition, Distribution, and Morphology . . . . . . . . . . . . . . . . . . . . . . . . 25 e. G. Plopper, A. Mir, J. St. George, N. Tyler, A. Mariassy, D. Wilson, S. Nishio, D. Cranz, J. Heidsiek, and D. Hyde Chapter 4. Comparative Metabolic Basis for the Disposition and Toxic Effects of Inhaled Materials . . . . . . . . . . . . . . . . . 41 A. R. Dahl Part II. Methodological Issues in Designing and Conducting Studies with Laboratory Animals Chapter 5. Exposure Facilities and Aerosol Generation and Characterization for Inhalation Experiments. . . . . . . . . .

Editors and Affiliations

  • Department of Veterinary Pathology, University of California, Davis, USA

    Donald L. Dungworth

  • Bayer AG, Institute for Toxicology, Wuppertal-Elberfeld, Germany

    Georg Kimmerle

  • Abbott Laboratories, USA

    James Lewkowski

  • Inhalation Toxicology Research Institute, Lovelace Biomedical and Environmental Research Institute, Albuquerque, USA

    Roger O. McClellan

  • Fraunhofer Institute of Toxicology and Aerosol Research, Hannover 61, Germany

    Werner Stöber

Bibliographic Information

  • Book Title: Inhalation Toxicology

  • Book Subtitle: The Design and Interpretation of Inhalation Studies and Their Use in Risk Assessment

  • Editors: Donald L. Dungworth, Georg Kimmerle, James Lewkowski, Roger O. McClellan, Werner Stöber

  • Series Title: ILSI Monographs

  • DOI: https://doi.org/10.1007/978-3-642-61355-5

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag New York Inc. 1988

  • Softcover ISBN: 978-3-642-64806-9Published: 23 September 2011

  • eBook ISBN: 978-3-642-61355-5Published: 07 March 2013

  • Edition Number: 1

  • Number of Pages: XIII, 318

  • Topics: Pathology, Pneumology/Respiratory System

Publish with us

Policies and ethics

Back to top

Search

Navigation