Molecular Signaling and Regulation in Glial Cells

1. Front Matter

   Pages I-XVI

   PDF

2. Signaling for Glial Cells

   1. Front Matter

      Pages 1-1

      PDF

   2. Cytokines, Growth Factors and Their Intracellular Cascades

      1. Origins and early development of oligodendrocyte precursor cells

         • Nigel Pringle, Wei-Ping Yu, Ellen J. Collarini, Andy Calver, Anita Hall, Sarah Guthrie et al.

         Pages 3-10

      2. Cytokine and Growth Factor Synthesis in Human Astrocytes

         • Francesca Aloisi, Francesca Ceccherini Silberstein, Giulio Levi

         Pages 11-19

      3. Mature Pig Astrocytes Do Not Respond to NGF as Oligodendrocytes Do

         • Hans H. Althaus, Tyede Schmidt-Schultz, Sabine Klöppner

         Pages 20-27

      4. Endopeptidase-24.11/common acute lymphoblastic leukaemia antigen CD10 in Schwann cells: Evidence for a role in nerve development and regeneration

         • Rebecca Matsas, Stathis Meintanis

         Pages 28-43

      5. Regulation of Oligodendrocyte Development by the LIF Cytokine Subfamily: Studies of the Neonatal Lineage Cultured from Rat Cerebrum

         • Anthony Gard, Wesley Williams II, Martha Burrell

         Pages 44-56

      6. HIV-1 Env and Glutamate Induction of NO, IL1, and TNF

         • Jean E. Merrill, Bruce D. Howard, Nigel T. Maidment

         Pages 57-68

      7. Protein Kinase C Stimulation Induces Astrocyte and Oligodendrocyte Proliferation, Demyelination and Enhanced Remyelination in Aggregating Rat Brain Cell Cultures

         • Jean-Marie Matthieu, Sandrine Pouly, Paid Honegger

         Pages 69-75

      8. Monosialogangliosides and Nerve Growth Factor Stimulate Synthesis of Glycoproteins in Glioma Cells

         • Ephraim Yavin

         Pages 76-88

   3. Ion Channels and Neurotransmitter Receptors

      1. Responses of Oligodendrocytes to Classical Neurotransmitters: Signaling Pathways

         • Guillermina Almazan, Amani Khorchid, Hsueh-Ning Liu, Eduardo Molina-Holgado

         Pages 91-100

      2. Ion channel expression and function in astrocytic scars

         • Harald Sontheimer, Elizabeth Fernandez-Marques

         Pages 101-113

      3. Ion Channel Expression in Glial Cells from Trout Central Nervous System

         • H. Rabe, G. Glassmeier, T.-D. Nguyen, G. Jeserich

         Pages 114-126

      4. Ion Channel Reorganization During Remyelination

         • Peter Shrager, Sanja D. Novakovi

         Pages 127-138

      5. Gap Junction Expression in Myelinating Cells

         • Rolf Dermietzel

         Pages 139-148

3. Genes and Proteins of Myelin

   1. Front Matter

      Pages 149-149

      PDF

   2. Structure, Regulations and Function

      1. CNS Myelination: What can we learn from phylogeny?

         • Robert M. Gould, Warren D. Spivack

         Pages 151-162

      2. The Proteolipid Protein Gene Family in the Central Nervous Systems of Fish

         • M. Yoshida, K. Kitagawa, D. R. Colman

         Pages 163-169

      3. Molecular Structure of Myelin Genes in the CNS of Trout

         • G. Jeserich, J. Strelau, A. Stratmann

         Pages 170-181

      4. Transcriptional Controls in the Oligodendrocyte Lineage

         • Lynn D. Hudson, Jin G. Kim, Claudia Wiese, Da-Lin Yao, Xia Liu, Henry F. de Webster et al.

         Pages 182-190

An excellent survey of the most recent advances in the area of cellular and molecular biology of glial cells and their involvement in remyelination and functional repair in the CNS. A major part of this book deals with signaling paths within and among neural cells. Glial cells (astrocytes, oligodentrocytes, microglial cells) themselves release substantial amounts of cytokines, growth factors and other signaling molecules, which play an important role during injury and regeneration. Another signaling route between neurons and glial cells follows ion channels and neurotransmitter receptors. In addition to animal models, human oligodentrocytes in cell culture and in the human MS brain are characterized with respect to their immunocytochemistry and function.

• Activation
• Development
• Multiple Sklerose
• Nervensystem
• Nervous System
• Regeneration
• glia
• glycoprotein
• growth factors
• multiple sclerosis
• myelination
• neurons
• phylogeny
• proteins
• regulation

• FB Biologie/Chemie, Universität Osnabrück, Osnabrück, Germany

  Gunnar Jeserich

• Max-Planck-Institut für Experimentelle Medizin, Göttingen, Germany

  Hans H. Althaus

• FB Biologie, Universität Oldenburg, Oldenburg, Germany

  Christiane Richter-Landsberg

• Molekulare Neurobiochemie, Universität Bochum, Bochum, Germany

  Rolf Heumann

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