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Progress and Perspective in the Treatment of Lung Cancer

  • Book
  • © 1999

Overview

Editors:
  1. P. Houtte

    1. Department of Radiation Oncology, Service de Radiothérapie, Institut Jules Bordet, Bruxelles, Belgium

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  2. J. Klastersky

    1. Service de Médecine Interne et Laboratoire d’Investigation Clinique H.J. Tagnon Centre des Tumeurs de l’Université Libre de Bruxelles, Institut Jules Bordet, Bruxelles, Belgium

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  3. P. Rocmans

    1. Service de Chirurgie Thoracique, Hôpital Erasme, Bruxelles, Belgium

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  • Comprehensive account of the progress in the treatment of lung cancer
  • Various therapeutic approaches are documented and appraised, with particular emphasis being placed on the benefits of a multimodality strategy

Part of the book series: Medical Radiology (MEDRAD)

Part of the book sub series: Radiation Oncology (Med Radiol Radiat Oncol)

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Table of contents (23 chapters)

  1. Front Matter

    Pages I-X
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  2. Prognostic Factors: From Clinical Parameters to New Biological Markers

    • J. B. Sørensen, K. Østerlind
    Pages 1-21

  3. Radiological Evaluation of Intrathoracic Extension and Resectability of Non-Small Cell Lung Cancer

    • J. A. Hanson, P. Armstrong
    Pages 23-38

  4. Positron Emission Tomography: A New Tool in Diagnosing, Staging, and Treatment Monitoring of Lung Cancer

    • C. Schiepers
    Pages 39-46

  5. Exclusive Surgery for Stage III Disease: Is It Still Ethical?

    • P. Rocmans, M. Cappello, P. De Francquen
    Pages 47-52

  6. Induction Chemotherapy with or without Radiotherapy Followed by Surgery in Non-Small Cell Lung Cancer

    • Kathy S. Albain
    Pages 53-71

  7. Adjuvant Therapy in Non-Small Cell Lung Cancer

    • S. S. Leong, C. M. S. Rocha Lima, M. R. Green
    Pages 73-83

  8. Induction or Concurrent Chemotherapy and Radiation Therapy for Locally Advanced Non-Small Cell Lung Cancer

    • R. Komaki, J. D. Cox
    Pages 85-94

  9. Exclusive Radiotherapy for NSC Lung Cancer

    • H.-P. Heilmann, F. Wuerschmidt, H. Buenemann
    Pages 95-108

  10. Three-Dimensional Conformal Radiotherapy in Treatment of Bronchogenic Carcinoma

    • B. Emami
    Pages 109-117

  11. Endoluminal Brachytherapy: A Curative Modality?

    • H. Marsiglia, P. Baldeyrou, E. Lartigau
    Pages 119-125

  12. Integration of Radiation Therapy and Chemotherapy for Small Cell Lung Cancer

    • H. Wagner
    Pages 127-137

  13. Role of Prophylactic Cranial Irradiation: Benefits and Late Effects

    • A. Gregor, A. Cull
    Pages 139-149

  14. Fractionation as a Biological Dose Modifier

    • M. I. Saunders
    Pages 151-159

  15. Biochemical and Biological Dose Modifiers for Irradiation of Lung Cancers

    • R. O. Mirimanoff
    Pages 161-172

  16. Intraoperative Radiotherapy for Lung Cancer

    • F. A. Calvo, J. J. Aristu, M. Moreno, M. Santos, S. A. Fisher
    Pages 173-182

  17. Should all Stage IV Non-Small Cell Lung Cancer Be Treated Palliatively?

    • F. Cappuzzo, A. Zappala, T. Le Chevalier
    Pages 183-189

  18. Intensive Therapy of Small Cell Lung Cancer: A Review of Recently Published Data

    • J. Klastersky, D. Devriendt
    Pages 191-198

  19. Best Supportive Care or Chemotherapy for Stage IV Non-Small Cell Lung Cancer

    • J. P. Sculier, T. Berghmans, C. Castaigne, Y. Lalami, S. Luce, C. Sotiriou et al.
    Pages 199-207

  20. Do We Have the Real Tools to Evaluate Lung Radiotoxicity?

    • F. Mornex, L. J. Boersma
    Pages 209-223
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Keywords

About this book

Lung cancer is not a single disease process but is a group of biologically variable diseases. Therefore, accurate and complete diagnosis along with complete workup of the patient prior to decision-making in treatment is essential to devise the most appropriate treatment strategy. In North America adenocarcinoma of the lung now accounts for about 40% of all lung cancers and stage for stage these tumors have a poorer prognosis than squamous cell cancers of the lung. Many prognostic indicators have been identified such as genetic markers and neuroen­ docrine differentiation, which have important roles to play in identifying the patients who would benefit most from active treatment. Screening and early detection have been thought to be sine qua non in early diagnosis of lung cancer. However, a number of controlled trials assessing the value of annual screening for lung cancer have demonstrated in some studies that chest X-rays and/or cytology screening may improve stage distribution, resectability, survival, and fatality but has not shown an impact on disease-specific mortality rates. The Mayo Clinic lung project compar­ ing quarterly chest X-rays and sputum cytology with routine care in more than 10 000 male smokers indicated that 5-year survival following treatment in the screened patients was better than rates in contemporary clinical practice. However, arguments have been ad­ vanced as to factors that might have biased the clinical benefits. Other trials are currently under way to deal with this issue along with new molecular markers that may enhance sputum sensitivity.

Editors and Affiliations

  • Department of Radiation Oncology, Service de Radiothérapie, Institut Jules Bordet, Bruxelles, Belgium

    P. Houtte

  • Service de Médecine Interne et Laboratoire d’Investigation Clinique H.J. Tagnon Centre des Tumeurs de l’Université Libre de Bruxelles, Institut Jules Bordet, Bruxelles, Belgium

    J. Klastersky

  • Service de Chirurgie Thoracique, Hôpital Erasme, Bruxelles, Belgium

    P. Rocmans

Bibliographic Information

  • Book Title: Progress and Perspective in the Treatment of Lung Cancer

  • Editors: P. Houtte, J. Klastersky, P. Rocmans

  • Series Title: Medical Radiology

  • DOI: https://doi.org/10.1007/978-3-642-59824-1

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1999

  • Hardcover ISBN: 978-3-540-62548-3Published: 25 February 1999

  • Softcover ISBN: 978-3-642-64140-4Published: 18 September 2011

  • eBook ISBN: 978-3-642-59824-1Published: 06 December 2012

  • Series ISSN: 0942-5373

  • Series E-ISSN: 2197-4187

  • Edition Number: 1

  • Number of Pages: X, 280

  • Number of Illustrations: 3 illustrations in colour

  • Topics: Pneumology/Respiratory System, Oncology, Surgery, Radiotherapy, Imaging / Radiology

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