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Immunobiology of Bacterial CpG-DNA

Editors:

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 247)

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Table of contents (16 chapters)

  1. Front Matter

    Pages I-IX
  2. Mechanism of Action of CpG DNA

    • A. M. Krieg, G. Hartmann, A.-K. Yi
    Pages 1-21
  3. Macrophage Activation by Immunostimulatory DNA

    • K. J. Stacey, D. P. Sester, M. J. Sweet, D. A. Hume
    Pages 41-58
  4. Hematopoietic Remodeling Triggered by CpG DNA

    • G. B. Lipford, T. Sparwasser
    Pages 119-129
  5. CpG DNA Augments the Immunogenicity of Plasmid DNA Vaccines

    • D. M. Klinman, K. J. Ishii, D. Verthelyi
    Pages 131-142
  6. CpG DNA in Cancer Immunotherapy

    • G. J. Weiner
    Pages 157-170
  7. Back Matter

    Pages 241-248

About this book

Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules and pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field.

Editors and Affiliations

  • Institut für Medizinische Mikrobiologie, Immunologie und Hygiene der Technischen Universität München, München, Germany

    Hermann Wagner

Bibliographic Information

  • Book Title: Immunobiology of Bacterial CpG-DNA

  • Editors: Hermann Wagner

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-642-59672-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE, part of Springer Nature 2000

  • Softcover ISBN: 978-3-642-64077-3Published: 26 September 2011

  • eBook ISBN: 978-3-642-59672-8Published: 06 December 2012

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: IX, 246

  • Topics: Immunology, Microbiology, Cancer Research

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access