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Platelets and Atherosclerosis

  • Book
  • © 1991

Overview

Editors:
  1. Christof Kessler

    1. Klinik für Neurologie der Medizinischen Universität zu Lübeck, Lübeck 1, Germany

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Table of contents (14 chapters)

  1. Front Matter

    Pages I-XII
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  2. The Role of Platelets in the Early Stages of Atherosclerosis

    • S. Moore
    Pages 1-9

  3. Proliferation of Vascular Smooth Muscle Cells in the Absence of Platelets. In Vivo Study in Deendothelialized Carotid Arteries of Thrombocytopenic Rats

    • J. Fingerle, R. Johnson, M. W. Majesky, A. W. Clowes, M. A. Reidy
    Pages 11-17

  4. The Role of Macrophages in Atherogenesis — Platelet-Monocyte Interactions

    • E. von Hodenberg, S. Heinen, M. Hauptmann, J. Kreuzer, H. Henningsen, W. Kübler
    Pages 19-24

  5. Animal Models Evaluating Platelet-Modifying Drugs

    • L. A. Harker
    Pages 25-30

  6. Preventive Measures to Reduce Injured Vessel Wall Thrombogenicity

    • M. R. Buchanan, M.-C. Bertomeu
    Pages 31-38

  7. Interactions Between Platelets in Whole Blood and a Thrombogenic Subendothelial Matrix: Acetylsalicylic Acid and Dipyridamole Inhibit Thrombus Formation Ex Vivo in Humans

    • T. H. Müller, W. G. Eisert
    Pages 39-44

  8. Human Endothelial Cells Modulate Thrombus Formation in an In Vitro Model of Platelet-Vessel Wall Interactions

    • T. H. Müller, W. G. Eisert
    Pages 45-52

  9. Cerebral Vasocontraction Induced by Thrombin-Stimulated Washed Human Platelets - A New In Vitro Model to Study Cerebral Vasospasm

    • M. Braun, H. Strobach, K. Schrör
    Pages 53-58

  10. Radioisotopic Monitoring of the Main Mechanisms Involved in Human Atherogenesis

    • H. Sinzinger, Irene Virgolini, P. Fitscha
    Pages 59-64

  11. Modification of Platelet Prosthetic Interaction by Endothelial Cells

    • M. Goldman, D. Gourevitch
    Pages 65-70

  12. Quantitation of Platelet Thrombus in Cardiac Valve Prostheses with the Radiolabeled Platelets

    • M. K. Dewanjee
    Pages 71-86

  13. 99mTc-HMPAO Thrombocytes: In Vitro Comparison with111In-Oxine Thrombocytes and Preliminary Clinical Experience

    • M. R. Hardeman
    Pages 87-93

  14. Thrombogenesis and Antithrombotic Agents in an In Vivo Model for Minimal Endothelial Damage

    • K. S. Herrmann
    Pages 95-99

  15. Indium-111 Platelet Scintigraphy in Stroke Patients

    • H. Henningsen
    Pages 101-107

  16. Back Matter

    Pages 109-110
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Keywords

About this book

Most patients with cerebrovascular diseases are treated with antiplatelet drugs. Basic thromosis research showed that platelets are an important factor in the pathogenesis of ar- therosclerosis and its complications, but other compounds as macrophages and vessel wall factors are also involved in this process. The aim of this volume is to connect labora- tory findings with clinical applications.

Editors and Affiliations

  • Klinik für Neurologie der Medizinischen Universität zu Lübeck, Lübeck 1, Germany

    Christof Kessler

Bibliographic Information

  • Book Title: Platelets and Atherosclerosis

  • Editors: Christof Kessler

  • DOI: https://doi.org/10.1007/978-3-642-58225-7

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin Heidelberg 1991

  • Softcover ISBN: 978-3-540-53006-0Due: 14 December 1990

  • eBook ISBN: 978-3-642-58225-7Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XII, 110

  • Number of Illustrations: 30 b/w illustrations

  • Topics: Neurology, Pharmacology/Toxicology, Nuclear Medicine, Cardiology

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